Quantcast

Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
August 01, 2014, 08:24:05 AM

Login with username, password and session length


Members
Stats
  • Total Posts: 632621
  • Total Topics: 47920
  • Online Today: 263
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: Increase in viral load. Blip? Resistance?  (Read 1497 times)

0 Members and 1 Guest are viewing this topic.

Offline HereIAm

  • Member
  • Posts: 68
Increase in viral load. Blip? Resistance?
« on: April 13, 2012, 03:07:28 PM »
Greetings Friends!

First, it has been a long time since I have logged on here.  When I was first diagnosed, as you can see in my signature line, I had pretty 'bad' numbers.

I began Atripla.  I had very few side-effects (just one technicolor like dream, darn it).   So, things have been good.  My viral load have been undetectible since 2009.  My CD4 and % have steadily, but SLOWLY improved.  The most recent CD4 was 360 at 19%.  So, not terrible, given where I started!

The real amazing part is that I feel much better.  I am able to think.  Work.  I basically live my life as if nothing is going on.   Well, nothing other than 100% adherence to the one Atripla a day -- the only irregularity was one time I was 4 hours late.  Otherwise, complete adherence, every day, every dose.

Now ...  About a month ago, I began having night sweats.  Then, I began having some aching in the knees.  I had both of these things when I was very sick, at diagnosis.

I got blood work done for my regular appointment.  Went to the appointment and found that I had a viral load of 6800!   Now, I know why I am having night sweats!  So, the doctor repeated the VL, the CD4 and ordered a new genotype.  We are waiting for those results.

What are others' experience with this?  This is new to me, at least the potential change in meds, resistance, etc.   

I have done some reading.  Here is what I am sure of.   1) My first genotype showed no resistance.  2) I have had NO new exposures.   3).  No missed doses and one 'late dose by 4 hours' since October 2008.   

If this is resistance, how?   Oh, you experienced ones, tell me!

Thanks for your future comments!!!

Tested Positive 10 Sept 2008.
24 Sept 2008:  CD 4: 23;   1%;  VL: 770,709
1st Oct 2008:  Started Atripla
4 Dec 2008:  CD 4: 145; 8%, VL: 209
1 March 2009:  CD 4: 91; 8%, VL: 49 (undet)
1 June 2009:  CD 4: 164; 11%, VL: 61
8 July 2011:  CD 4: 286; 17%, VL Undet
28 Oct 2011: CD 4: 346; 21%, VL Undet
2 Mar 2012: CD 4: 316; 20%, VL 6800 (probably an error)
12 Apr 2012: CD 4: 333; 21%, VL Undet

Offline Ann

  • Administrator
  • Member
  • Posts: 28,140
  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Increase in viral load. Blip? Resistance?
« Reply #1 on: April 14, 2012, 08:02:43 AM »
That's a bit of a tricky one - 6800 is a little high to be a blip, but it still could be a blip (and very possibly a lab error), particularly given your excellent adherence.

Feeling unwell recently could very well be a coincidence. You and your doctor might want to look into other possible causes for the problems you're experiencing. For example, have you been screened for hep C? Hep C can also cause night-sweats and joint pain.

I think you're just going to have to wait for the new results and try to not worry too much in the meantime. I know, easier said than done, but do your best to keep your mind off the results before you get them. Hang in there!

Keep us posted. Hopefully this is just a blip or lab-error.
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline HereIAm

  • Member
  • Posts: 68
Re: Increase in viral load. Blip? Resistance?
« Reply #2 on: April 15, 2012, 07:14:37 PM »
Thanks, Ann!

I will let you know what the Dr. says!  Who knows.  But, I feel certain we will get to the bottom of it.

I appreciate your comments.  I feel great support here in these forums.

Here!
Tested Positive 10 Sept 2008.
24 Sept 2008:  CD 4: 23;   1%;  VL: 770,709
1st Oct 2008:  Started Atripla
4 Dec 2008:  CD 4: 145; 8%, VL: 209
1 March 2009:  CD 4: 91; 8%, VL: 49 (undet)
1 June 2009:  CD 4: 164; 11%, VL: 61
8 July 2011:  CD 4: 286; 17%, VL Undet
28 Oct 2011: CD 4: 346; 21%, VL Undet
2 Mar 2012: CD 4: 316; 20%, VL 6800 (probably an error)
12 Apr 2012: CD 4: 333; 21%, VL Undet

Offline Ann

  • Administrator
  • Member
  • Posts: 28,140
  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Increase in viral load. Blip? Resistance?
« Reply #3 on: April 16, 2012, 06:44:08 AM »
You're very welcome. That's what we're here for! Be sure to let us know how it all turns out. I've got my fingers crossed for you that it's just a blip or lab error. :)
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline SoSadTooBad

  • Member
  • Posts: 248
Re: Increase in viral load. Blip? Resistance?
« Reply #4 on: April 17, 2012, 12:43:42 AM »
I had a "blip" that was 3600 and it totally freaked me out.  It really was a blip and it went right back to undetectible within a few days.   Hang in there.

Offline HereIAm

  • Member
  • Posts: 68
Re: Increase in viral load. Blip? Resistance?
« Reply #5 on: April 17, 2012, 09:34:43 PM »
Thanks for the comment, SoSadTooBad! 

I will keep you posted!  New appointment on the 26th!
Tested Positive 10 Sept 2008.
24 Sept 2008:  CD 4: 23;   1%;  VL: 770,709
1st Oct 2008:  Started Atripla
4 Dec 2008:  CD 4: 145; 8%, VL: 209
1 March 2009:  CD 4: 91; 8%, VL: 49 (undet)
1 June 2009:  CD 4: 164; 11%, VL: 61
8 July 2011:  CD 4: 286; 17%, VL Undet
28 Oct 2011: CD 4: 346; 21%, VL Undet
2 Mar 2012: CD 4: 316; 20%, VL 6800 (probably an error)
12 Apr 2012: CD 4: 333; 21%, VL Undet

Offline HereIAm

  • Member
  • Posts: 68
Re: Increase in viral load. Blip? Resistance?
« Reply #6 on: April 26, 2012, 05:49:55 PM »
Follow up.....

Here are the lastest results.  CD4: 333, 21% and VL <50 (undet).

The doctor says while lab errors are not the norm, she thinks the 6800 result I had was a lab error and not anything to worry about.  Though, I will see her a bit more often for the rest of this year, to be sure.

Thanks for your kind words here.

Tested Positive 10 Sept 2008.
24 Sept 2008:  CD 4: 23;   1%;  VL: 770,709
1st Oct 2008:  Started Atripla
4 Dec 2008:  CD 4: 145; 8%, VL: 209
1 March 2009:  CD 4: 91; 8%, VL: 49 (undet)
1 June 2009:  CD 4: 164; 11%, VL: 61
8 July 2011:  CD 4: 286; 17%, VL Undet
28 Oct 2011: CD 4: 346; 21%, VL Undet
2 Mar 2012: CD 4: 316; 20%, VL 6800 (probably an error)
12 Apr 2012: CD 4: 333; 21%, VL Undet

Offline Cojo

  • Member
  • Posts: 189
Re: Increase in viral load. Blip? Resistance?
« Reply #7 on: May 02, 2012, 07:47:08 PM »
Great news indeed! This is also a good reminder for all of us that both lab errors and blips do happen and all turns out well in the end.
May 2011 - Tested Positive
June 2011 - CD4 330   16%   VL182,000 no resistance
Oct 6, 2011 - CD4 300  20%  VL 60,000
Oct 7, 2011 - start Truvada / Isentress
Nov 29, 2011 CD4 280 26% VL 54
Feb 7 2012 CD4 260 25% UD!
Mar 20 2012 CD4 400 28%
June 2012 CD4 330 26% UD
Sept 2012 CD4 450 32% UD
Dec 2012 CD4 310 28% UD
May 2013 CD4 500 32% UD
Oct 2013 CD4 460 33% UD
May 2014 CD4 360 33% UD

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.