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Author Topic: Question about CD-4 and VL  (Read 2198 times)

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Offline Parker78

  • Member
  • Posts: 10
Question about CD-4 and VL
« on: April 11, 2012, 09:43:21 PM »
Hi everyone, 

I tested HIV+ on February 27th of this year.  I had gotten tested just 6 months prior and was negative, so the infection was definitely recent.  I went to the doctor a few days after finding out and by blood tests revealed a CD-4 count of 584 and a very high VL of 146k.    My hope is to hold off on starting meds as long as possible (until i hit 500).   My questions are the following:

1.  The CD-4 count is so close to 500 so soon after infection.  Is this a sign that my CD-4 count is going to go down very fast?
2.  Does the VL being so high also mean the CD-4 number will go faster?

Thanks for any help!  Just a little nervous here.  I know there is no exact science answer and everyone is different, but just looking for some guidance.

Offline Dr.Strangelove

  • Member
  • Posts: 215
Re: Question about CD-4 and VL
« Reply #1 on: April 11, 2012, 10:00:09 PM »
The relationship between CD4 and VL is not very straightforward. And every person is different.
When I was first diagnosed (like you, only a few months after seroconversion) my VL was below 100. Despite of that my CD4 was only 370. 3 Months later the CD4 recovered to 650 and the VL was still very low, around 300.

It's normal for the values to jump. You need more data points to get an idea about the long term trend. Anything else is just speculation...

Offline Valmont

  • Member
  • Posts: 334
Re: Question about CD-4 and VL
« Reply #2 on: April 12, 2012, 12:41:29 AM »
I m in a similar situation, diagnosticked very soon after infection I think, in may 2011...

My first VL was 170k and cd4 were 505, 6 months after that my CDs were 714 and VL 80K...

For sure high VL generate me fear and makes me a little worried...  Anyway, soon or late you ll have to go on med, so being worried for that is not so justified...

There is no rule definitively, every one reacts different.

The most important is you cd4 are great, by the way you have to get another blood result in a few month because a single set is very little to know exactly how you are...

... These are good results !

Take care...
Apr 2011: Diagnotized
Jun 2011: CD4: 504  VL: 176.000
Dic 2011: CD4: 714  VL: 95.000
May 2012: CD4: 395 VL: 67.000
Jun 2012: CD4: 367
Agu 2012: Starting Emtricitabine 200 mg / Tenofovir 300 mg and Efavirenz 600 mg (2 pills) different brands or VIRADAY/ATRIPLA/Mylan....
Sep 2012: VL: 138
Dic 2012: CD4: 708 VL: <34  %CD4: 32%
Jan 2013: CD4: 707 VL: <20
May 2013: CD4: 945 VL: <34 %CD4: 33%
Agu 2013: CD4: 636 VL: <34 %CD4: 50%
Dic 2013: Latent TB, started Isoniazid

Offline liketheboat

  • Member
  • Posts: 44
Re: Question about CD-4 and VL
« Reply #3 on: April 12, 2012, 01:12:36 AM »
also keep in mind that new treatment guidlines just came out that reccomend treatment for all HIV infected people, regarless of cd4 count.
Memorial Day 2010 Seroconverted
Labor Day 2010 tested positive
Oct 2010 cd4 359 vl 6,500
Dec 2010 cd4 vl 306
Jan 2011 started Atripla
Feb 2011 cd4 250 vl ud
April 2011 cd4 399 vl ud
June 2011 cd4 293 vl ud
October 2011 cd4 354 vl ud
March 2012 cd4 561 vl ud


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