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Author Topic: Milk Thistle interaction with Truvada and Viramune  (Read 1652 times)

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Offline pozzitive

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Milk Thistle interaction with Truvada and Viramune
« on: January 23, 2012, 01:12:38 AM »
Everything I read about Milk Thistle seems great but I can't find any solid information on its interaction with my drugs Truvada and Viramune.
Before I ask my doctor I decided to try here and see if yiy guys know of anything? If you have tried it and felt a difference in your overall health.
POZ since 2000 \ Truvada and Viramune

"I can be changed by what happens to me. but I refuse to be reduced by it.


Offline Ann

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Re: Milk Thistle interaction with Truvada and Viramune
« Reply #1 on: January 23, 2012, 06:09:21 AM »
I checked the interaction charts at http://www.hiv-druginteractions.org/ and it seems there is a potential interaction between Nevirapine (Viramune) and Milk Thistle, but none is expected between the meds in Truvada and Milk Thistle.

For the Viramune and MT; Potential interaction may require close monitoring, alteration of drug dosage or timing of administration.

While the site does not spell out what the potential interaction may be, I would imagine it may either decrease or increase the amount of Viramune in your system. As Viramune is cleared by the liver, my bet would be that it could decrease the Viramune. That's not something you want to happen, due to possible resistance issues.

I've always been wary of the claims about Milk Thistle myself. I've read reports where it can actually mask damage being done to the liver by artificially decreasing liver enzyme markers. It can also mess with meds that are metabolised through the liver. I stay away from it myself, but that's just me. You'll have to make your own mind up.

And of course, discuss it with your doctor.
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Offline pozzitive

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Re: Milk Thistle interaction with Truvada and Viramune
« Reply #2 on: February 06, 2012, 01:51:41 PM »
I think I will follow your wise advice.
Thnaks a lot!
POZ since 2000 \ Truvada and Viramune

"I can be changed by what happens to me. but I refuse to be reduced by it.



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