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Author Topic: START Study-Meds  (Read 1930 times)

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Offline shermanjd

  • member
  • Posts: 1
START Study-Meds
« on: August 10, 2011, 01:28:14 PM »
I am recently enrolled in the START study which is studying when people should start meds.  on Friday I get randomized and will either start meds or not.  I have been positive since jan. 2010 and my tcells have all been above 500.  The highest viral load was 70000 and now it's at 11000.  If I start meds, my doctor gave me the option of atripla or the combination of truvada, reyataz and norvir.  Anyone have any recommendations? I've been reading a lot of posts and it seems it is all running together now.   Thanks everyone for your help!  New to the site!
1/2010-tested poz 
9/2010-cd4:  969   vl:  70410  28%
1/2011-cd4:  897   vl:  12582
7/2011-cd4:  701   vl:  11139
8/2011-cd4:  570 (SMART study count

Offline mikeyb39

  • Member
  • Posts: 930
Re: START Study-Meds
« Reply #1 on: August 10, 2011, 03:01:05 PM »
i think i would do the Atripla route.  i've heard side effects with norvir are more prevalant.  I take Atripla and it seems to be working well for me...one pill a day before bed.  or possibly the new drug Edurant, Truvada combo.
11/02/2010  cd4-251, vl-591000
12/09/2010  started Atripla
02/18/2011  cd4-425, vl-800
06/10/2011  cd4-447, vl-70
10/10/2011  cd4-666, vl-80
01/05/2012  swiched med (prezista,norvir ,isentress, )
02/10/2012  cd4-733, vl-UD  Viread removed
06/10/2012  cd4-614, vl-UD
12/14/2012  cd4-764, vl-UD
09/01/2013  cd4-785, vl-UD
03/06/2014. cd4- 1078, VL-UD
09/05/2014  cd4-850 , VL-UD

Offline spacebarsux

  • Member
  • Posts: 1,350
  • Survival of the Fittest
Re: START Study-Meds
« Reply #2 on: August 10, 2011, 03:44:02 PM »
Hey Sherman. Welcome to the forums.

I wanted to particpate in the START clinical trial as well, but where I am it seems unlikely since the only hospitals that are partaking in the study are not in my city.
Infected-  2005 or early 2006; Diagnosed- Jan 28th, 2011; Feb '11- CD4 754 @34%, VL- 39K; July '11- CD4 907@26%,  VL-81K; Feb '12- CD4 713 @31%, VL- 41K, Nov '12- CD4- 827@31%

Offline shermanjd

  • member
  • Posts: 1
Re: START Study-Meds
« Reply #3 on: August 10, 2011, 10:37:50 PM »
i think i would do the Atripla route.  i've heard side effects with norvir are more prevalant.  I take Atripla and it seems to be working well for me...one pill a day before bed.  or possibly the new drug Edurant, Truvada combo.

Thanks for your input.  My doctor said she is ok with any, it all depends on what I want for side effects, if I end up having any.  I've never had any problem with any meds before. 
1/2010-tested poz 
9/2010-cd4:  969   vl:  70410  28%
1/2011-cd4:  897   vl:  12582
7/2011-cd4:  701   vl:  11139
8/2011-cd4:  570 (SMART study count

Offline shermanjd

  • member
  • Posts: 1
Re: START Study-Meds
« Reply #4 on: August 10, 2011, 10:39:06 PM »
Hey Sherman. Welcome to the forums.

I wanted to particpate in the START clinical trial as well, but where I am it seems unlikely since the only hospitals that are partaking in the study are not in my city.

Where do you live?  It was such a hard decision to make even just to join the Study.  I'm happy I did it though..
1/2010-tested poz 
9/2010-cd4:  969   vl:  70410  28%
1/2011-cd4:  897   vl:  12582
7/2011-cd4:  701   vl:  11139
8/2011-cd4:  570 (SMART study count

Offline spacebarsux

  • Member
  • Posts: 1,350
  • Survival of the Fittest
Re: START Study-Meds
« Reply #5 on: August 12, 2011, 05:47:50 AM »
Where do you live?  It was such a hard decision to make even just to join the Study.  I'm happy I did it though..

I am in Delhi, India (North India). I know there's one hospital in Pune (West India) and 2 in Chennai (South India) particiapting in the START study. I rang them and they told me it won't be possible for me to participate due to my domicile.

Have you decided if you will be starting meds or not?
Infected-  2005 or early 2006; Diagnosed- Jan 28th, 2011; Feb '11- CD4 754 @34%, VL- 39K; July '11- CD4 907@26%,  VL-81K; Feb '12- CD4 713 @31%, VL- 41K, Nov '12- CD4- 827@31%

Offline hubsen

  • Member
  • Posts: 17
Re: START Study-Meds
« Reply #6 on: August 15, 2011, 04:42:26 PM »
Choose Atripla. One pill -> once a day!
Really easy to manage...
28/08/10 Infected
09/10 Diagnosed positive
09/10 CD4 563 VL 1,1K
10/10 CD4 327 VL 0,37K
10/10 CD4 382 VL 0,13K
11/10 CD4 454 VL 0,28K
12/10 CD4 569 VL 0,068K
04/11 CD4 383 VL 68000
05/11 CD4 405 VL 94000
06/06/11 Started on Atripla
07/11 CD4 537 VL     870
09/11 CD4 682 VL       25
12/11 CD4 641 VL.      UD
03/12 CD4 799 VL.      UD
09/12 CD4 870 VL.      UD
10/12 CD4 812 VL.      UD
11/12 CD4 901 VL.      UD
12/12 CD4 1051 VL.     UD
03/13 CD4  707 VL.     UD
09/13 CD4 1022 VL.    UD

Offline Billy B

  • Member
  • Posts: 374
Re: START Study-Meds
« Reply #7 on: August 19, 2011, 12:35:58 PM »
I am recently enrolled in the START study which is studying when people should start meds.  on Friday I get randomized and will either start meds or not.  I have been positive since jan. 2010 and my tcells have all been above 500.  The highest viral load was 70000 and now it's at 11000.  If I start meds, my doctor gave me the option of atripla or the combination of truvada, reyataz and norvir.  Anyone have any recommendations? I've been reading a lot of posts and it seems it is all running together now.   Thanks everyone for your help!  New to the site!

Hi Sherman- Do you know know why they did not offer Isentress & Truvada?
Peace,
Billy
« Last Edit: August 20, 2011, 11:24:39 AM by Billy B »
VL 4420 CD4 340 CD4% 24   3/15/10 Started I&T
VL  UD   CD4 340 CD4% 26.5 05/13/10
VL  UD   CD4 360 CD4% 27.1 08/3/10
VL  UD   CD4 310 CD4% 28.4 11/22/10
VL  UD   CD4 420 CD4% 27.9 02/11/11
VL  UD   CD4 370 CD4% 26.4 06/08/11
VL  UD   CD4 360 CD4% 27.7 09/23/11
VL  UD   CD4 370 CD4% 28.3 01/20/12
VL  UD   CD4 430 CD4% 28.8 05/11/12
VL  UD   CD4 370 CD4% 28.1 09/07/12
VL  UD   CD4 390 CD4% 32.3 03/14/13

Offline newt

  • Member
  • Posts: 3,885
  • the one and original newt
Re: START Study-Meds
« Reply #8 on: August 19, 2011, 02:18:27 PM »
Quote
Do you know why idea they did not offer Isentress & Truvada?

A good question, the study protocol permits all licensed antiretroviral medications.

- matt
"The object is to be a well patient, not a good patient"

Offline shermanjd

  • member
  • Posts: 1
Re: START Study-Meds
« Reply #9 on: August 24, 2011, 04:42:05 PM »
Hi Sherman- Do you know know why they did not offer Isentress & Truvada?
Peace,
Billy


Hi there.  I'm really not sure.  My doctor suggested those to me.  UPDATE:  I was chosen to be in the deferred group, so I won't be starting meds.  I will ask her next time I see her about that combo though. 
1/2010-tested poz 
9/2010-cd4:  969   vl:  70410  28%
1/2011-cd4:  897   vl:  12582
7/2011-cd4:  701   vl:  11139
8/2011-cd4:  570 (SMART study count

 


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