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Author Topic: HAART after 50  (Read 1504 times)

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Offline mikeyb39

  • Member
  • Posts: 921
HAART after 50
« on: July 11, 2011, 12:30:47 PM »
I was just reading an article in our local 'Voice' magazine here in texas from a reporter who says below

"Even if an older American has abundant financial resourses to access whatever medical treatment available, the true is that the drug cocktails that have prolonged the lives of younger people just don't work as well for anyone over 50, according to scientifi studies"

Anyone have any comments about that?  i'm 40 yrs old so 50 doesn't seem that far off...lol
11/02/2010  cd4-251, vl-591000
12/09/2010  started Atripla
02/18/2011  cd4-425, vl-800
06/10/2011  cd4-447, vl-70
10/10/2011  cd4-666, vl-80
01/05/2012  swiched med (prezista,norvir ,isentress, )
02/10/2012  cd4-733, vl-UD  Viread removed
06/10/2012  cd4-614, vl-UD
12/14/2012  cd4-764, vl-UD
09/01/2013  cd4-785, vl-UD
03/06/2014. cd4- 1078, VL-UD

Offline Assurbanipal

  • Member
  • Posts: 2,173
  • Taking a forums break, still see PM's
Re: HAART after 50
« Reply #1 on: July 11, 2011, 01:35:03 PM »
Let me put on my reading glasses sonny.   :)



I started HAART a couple of months before turning 50.   (5 years ago).

In the longevity studies the best results seem to be for people who get an undetectable viral load and can get their tcell counts back up to the normal range.  A large study has shown near normal life expectancy in those circumstances. 

But even for those who don't get tcell counts back into the normal range, if they stick with the drugs and get to an undetectable viral load there is a strong likelihood of living to retirement ages, it is just a little more likely that people with fewer tcells will die prematurely which brings the average age at death down (i.e. decreases the life expectancy)

The older you are when you start HAART the longer it takes / less likely you are to get tcell counts back into the normal range. 

So there is a kernel of truth somewhere here.  But it appears the reporter has misunderstood it and blown it out of proportion.


Creakily,
Assurbanipal
5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%

Offline mecch

  • Member
  • Posts: 11,254
  • red pill? or blue pill?
Re: HAART after 50
« Reply #2 on: July 11, 2011, 03:12:48 PM »
HAART works for people of any age.  The author is spitting hairs for some reason or other.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline newt

  • Member
  • Posts: 3,877
  • the one and original newt
Re: HAART after 50
« Reply #3 on: July 11, 2011, 06:08:28 PM »
Some aspects of immune restoration are more difficult for older people. In practice older here means over 30-40 (it's related to the thymus which don't work so well after then to produce new CD4 cells). But in terms of the final outcome, longevity, it might not be significant. Older people lose some CD4 cells each year, but being older, you might not need as many cos there will be less time left to lose them. This said, over 50 and HIV+? Start treatment? Good idea. It's not all about CD4 counts, it's also about accelerated cellular ageing and cardiovascular heath etc.

- matt
"The object is to be a well patient, not a good patient"

Offline aztecan

  • Member
  • Posts: 5,384
  • 29 years positive, 56 years a pain in the butt
Re: HAART after 50
« Reply #4 on: July 13, 2011, 03:30:55 PM »
. . . over 50 and HIV+? Start treatment? Good idea. It's not all about CD4 counts, it's also about accelerated cellular ageing and cardiovascular heath etc.
- matt


As one of the more seasoned members of the forum (read: over 50 and poz), I would certainly concur with Matt. As we get older, we have to take more care of ourselves, which means perhaps starting meds more quickly than our younger counterparts. We also have to watch other things, as make referred to, to ensure continued cardiovascular, pulmonary and other health areas.

HUGS,

Mark
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline OneTampa

  • Member
  • Posts: 2,104
  • "Butterflies are free."
Re: HAART after 50
« Reply #5 on: July 13, 2011, 05:40:16 PM »
As someone who has been HIV+ for 26 years and will be 58 this year, I reached my highest CD4 counts ever 2 1/2 years ago at over 800!  I am going into my 11th year non-detectable.  All of this, as I have stated before, on reduced dosage HIV meds for the last 10 years. So, my personal experience runs counter to the supposed less than stellar treatment results that may be tied to an after 50 age benchmark.
« Last Edit: July 13, 2011, 05:43:27 PM by OneTampa »
"He is my oldest child. The shy and retiring one over there with the Haitian headdress serving pescaíto frito."

Offline emeraldize

  • Member
  • Posts: 3,335
Re: HAART after 50
« Reply #6 on: July 13, 2011, 06:09:28 PM »
I started HAART at 57 -- maybe I missed the super-small print that said I shouldn't even try. Kidding aside, my VL dropped promptly to UD and my CD are moving up.

Offline sam66

  • Member
  • Posts: 277
  • Keep The Faith ; Fight The Fight
Re: HAART after 50
« Reply #7 on: July 15, 2011, 09:18:41 AM »

  On HARRT  3 years,  UD after 2 months, CD 677 from 274.    50 years old now

  Doing fine, loving life,  no probs apart from high cholesterol

  Tomorrow is a another day  ;)
december 2007 diagnosed +ve ,

Offline Billy B

  • Member
  • Posts: 374
Re: HAART after 50
« Reply #8 on: July 15, 2011, 11:22:57 AM »
Nearly 56 and went UD fairly soon after starting meds. I have not seen huge increases in CD4s but I am healthy. My IDS did say that most older people take longer to increase their CD4 counts because of the way the immune system works but that the most important thing was to become UD and have stable or increasing CD4%. I am thrilled to be on a combo that agrees with my body and my work schedule.
Peace,
Billy
« Last Edit: July 15, 2011, 06:23:33 PM by Billy B »
VL 4420 CD4 340 CD4% 24   3/15/10 Started I&T
VL  UD   CD4 340 CD4% 26.5 05/13/10
VL  UD   CD4 360 CD4% 27.1 08/3/10
VL  UD   CD4 310 CD4% 28.4 11/22/10
VL  UD   CD4 420 CD4% 27.9 02/11/11
VL  UD   CD4 370 CD4% 26.4 06/08/11
VL  UD   CD4 360 CD4% 27.7 09/23/11
VL  UD   CD4 370 CD4% 28.3 01/20/12
VL  UD   CD4 430 CD4% 28.8 05/11/12
VL  UD   CD4 370 CD4% 28.1 09/07/12
VL  UD   CD4 390 CD4% 32.3 03/14/13

Offline mikeyb39

  • Member
  • Posts: 921
Re: HAART after 50
« Reply #9 on: July 15, 2011, 01:28:09 PM »
thanks all for the replies    ;D
11/02/2010  cd4-251, vl-591000
12/09/2010  started Atripla
02/18/2011  cd4-425, vl-800
06/10/2011  cd4-447, vl-70
10/10/2011  cd4-666, vl-80
01/05/2012  swiched med (prezista,norvir ,isentress, )
02/10/2012  cd4-733, vl-UD  Viread removed
06/10/2012  cd4-614, vl-UD
12/14/2012  cd4-764, vl-UD
09/01/2013  cd4-785, vl-UD
03/06/2014. cd4- 1078, VL-UD

Offline emeraldize

  • Member
  • Posts: 3,335
Re: HAART after 50
« Reply #10 on: July 15, 2011, 04:46:40 PM »
We're happy to be able to supply them!!!

 


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