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Author Topic: Sav001h New Aids vaccine ready for human trials  (Read 4515 times)

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Offline butpoz

  • Member
  • Posts: 27
Sav001h New Aids vaccine ready for human trials
« on: July 02, 2011, 01:09:26 AM »
Toronto, July 02: The Canadian University of Western Ontario has developed a new HIV/Aids vaccine that is ready for human trials.

The vaccine called SAV001H has been developed by the university at London, about 160 km from Toronto, in collaboration with Sumagen Canada, a subsidiary of the Korean pharmaceutical company.

In a statement Tuesday, Sumagen Canada said it has submitted an application to the US Food and Drug Administration (FDA) to begin the first phase of trials of the vaccine on human beings.

Chil-Yong Kang, a professor at the university, said they have completed safety and immunogenicity studies of the vaccine on animals. Immunogenicity measures the ability of a drug or vaccine to provoke an immune response in the body. Trials of the new vaccine on animals have reportedly resulted in good anti-body reactions with no adverse effects.

Numerous trials have been carried out by pharmaceutical companies to develop vaccines , but no commercialised vaccine has been developed so far. Sumagen Canada has secured patents for the vaccine in over 70 countries, including the US, the European Union and Korea.

It said the phase one clinical trials of the vaccine will double check its safety on HIV positive volunteers. The phase two trials would assess the immunogenicity of the vaccine. Sumagen Canada said it is ready for clinical trials in the US as soon the FDA approval is granted.

The University of Western Ontario and the city of London have been short-listed by the Canadian government to set up an $88 million HIV vaccine manufacturing facility, which will be partly funded by the Bill and Melinda Gates Foundation.

Last week Canadian scientists had announced a major breakthrough in Aids treatment by saying that they have found where the HIV virus hides in the human body.

Currently, Aids patients have to take a cocktail of six drugs to prolong their life up to 13 years. There are over 33 mn HIV patients worldwide, with 2.7 million more getting infected each year.
http://www.siasat.com/english/content/new-aids-vaccine-ready-human-trials

P.s. Do you know where above "up to 13 years" above come from?


Offline LPinUK

  • Member
  • Posts: 58
Re: Sav001h New Aids vaccine ready for human trials
« Reply #1 on: July 02, 2011, 05:29:54 AM »
The comment that ARV's prolong life by "up to 13 years" removes any credibility whatsoever from this article.
Diagnosed Poz September 2003, Current Regimen Truvada & Sustiva.

Offline dpb

  • Member
  • Posts: 89
Re: Sav001h New Aids vaccine ready for human trials
« Reply #2 on: July 04, 2011, 01:48:47 PM »
The comment that ARV's prolong life by "up to 13 years" removes any credibility whatsoever from this article.

Agreed.  I continually read inaccurate articles stating that antiretroviral therapy increases lifespans by only 10-30 years, for example. 

According to my infectious disease doctor, my life expectancy is normal.  He told me that I'll die with HIV; not from it.  Where do these authors get these outlandish "facts" from, 1996?
Date        CD4    %    VL
1/15/11    Diagnosed
3/1/11    525    18    168,518
5/12/11    558    16    331,791
5/16/11    Started Atripla
5/31/11    NA    NA    1,200
6/15/11    721    21    330
7/15/11    649    23    231
8/15/11    569    25    UD
11/17/11  752    26    UD
3/1/12    634    27    UD
7/2/12    594    26    UD
2/13       676    30    UD
9/13       662    31    UD

Offline wolfter

  • Member
  • Posts: 4,391
Re: Sav001h New Aids vaccine ready for human trials
« Reply #3 on: July 04, 2011, 02:18:02 PM »
Wow, I must be on borrowed time then. 
productivity breeds content

Offline metekrop

  • Member
  • Posts: 354
Re: Sav001h New Aids vaccine ready for human trials
« Reply #4 on: July 06, 2011, 03:26:46 PM »

In a statement Tuesday, Sumagen Canada said it has submitted an application to the US Food and Drug Administration (FDA) to begin the first phase of trials of the vaccine on human beings.



Good news.  But why they need to apply to the US FDA?
Diag on Dec 8, 2000, CD 440 VL 44K, No Meds
Dec/08 - Feb/09 CD< 50 & VL >500k hosp'z.
St. Atripla - July/09 CD 179, VL 197k
Oct/09 CD 300 VL UD Chol 267
Mar/10 CD 468 UD, Ch 220
Aug/10 CD 460 UD, Ch 195
Dec/10 CD 492 UD, Ch 172
Mar/11 CD 636 UD, Ch 201
Aug/11 CD 530 UD, Ch 98
Jan/12 cd 616 UD, ch 189
Jul/12 CD 640 UD, Ch ?
Dec/12 CD 669 Ud, Ch 125
May/7 CD711 Ud, Ch?
Nov/ 22 663 UD, Ch,
April 17 CD 797, UD

 


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