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Author Topic: Question for Newt  (Read 2196 times)

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Offline Betelgeuse

  • Member
  • Posts: 163
Question for Newt
« on: June 15, 2011, 03:34:24 AM »
In reading through some of your older posts, I often see you make a reference to meds being "nukes" and "non-nukes". 

I tried googling its definition but it seems to be colloquial jargon used by members here. 

What exactly do you mean by this?  Couldn't figure it out contextually :(
04/19/11 - Diagnosed positive
04/29/11 - CD4 188 @ 12.5% / VL 18k
05/03/11 - CD4 171 @ unk% / VL 7k
06/04/11 - Start Truvada/Isentress
07/11/11 - CD4 not tested / VL UD
09/07/11 - CD4 252 @ unk% / VL UD

Offline ad2san

  • Member
  • Posts: 187
Re: Question for Newt
« Reply #1 on: June 15, 2011, 04:39:14 AM »
Hello supernova,

well this is lovely question, I trust me to answer for Newt  ;D
http://aids.about.com/od/hivmedicationfactsheets/a/nrti.htm

Cheers


Feb   2009 CD4 358 VL 2000 16%
May  2009 CD4 305 VL 3069  14% <---- Started TVD+ATZ/r
Jul  2009 CD4 512 VL <50   18%
Jul 2010 CD4 418 VL <50 24%                     
Switched to Kivexa (Epzicom) + Norvir + Reyataz (due to sleep problem)
Aug 2010 CD4 606 VL <50 25%
Jul 2011 CD4 494 UD 23%
Switched to Kivexa (Epzicom) + Viramune XR (due to kidney problems)
January 2012 CD4 564 UD 31%
October 2012 CD4 684 UD 29%
January 2013 CD4 594 UD 26%
Switched to Kivexa (Epzicom) + Isentress due to BIG increase GammaGT
Feb 2013 CD4 699 UD 28%
May 2013 CD4 385 UD 28%
July 2013 CD4 CD4 636 UD 25%
Oct 2013 CD4 588 UD 39%
Aug 2014 CD4 639 UD 25%

Offline Ann

  • Administrator
  • Member
  • Posts: 28,140
  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Question for Newt
« Reply #2 on: June 15, 2011, 05:44:01 AM »
In reading through some of your older posts, I often see you make a reference to meds being "nukes" and "non-nukes". 

I tried googling its definition but it seems to be colloquial jargon used by members here. 

What exactly do you mean by this?  Couldn't figure it out contextually :(

This is covered in our extensive Lessons section, specifically in the HIV Life-cycle Lesson.

In a nutshell, nukes are a shorthand way of saying Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs) and non-nukes are shorthand for Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs). Read the lessons so you can learn what they are and what they do.

Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline newt

  • Member
  • Posts: 3,878
  • the one and original newt
Re: Question for Newt
« Reply #3 on: June 15, 2011, 10:07:12 AM »
Well said all

There's a handy diagram here:

http://i-base.info/guides/starting/hiv-lifecycle

- matt
"The object is to be a well patient, not a good patient"

Offline Betelgeuse

  • Member
  • Posts: 163
Re: Question for Newt
« Reply #4 on: June 15, 2011, 12:48:19 PM »
I'm a little embarrassed. I didn't know there was a lesson for THAT. 

If there was a lesson on how to keep from losing my car keys I'd be all set.

Thanks guys.
04/19/11 - Diagnosed positive
04/29/11 - CD4 188 @ 12.5% / VL 18k
05/03/11 - CD4 171 @ unk% / VL 7k
06/04/11 - Start Truvada/Isentress
07/11/11 - CD4 not tested / VL UD
09/07/11 - CD4 252 @ unk% / VL UD

Offline Hellraiser

  • Member
  • Posts: 4,136
  • Semi-misanthropic
Re: Question for Newt
« Reply #5 on: June 15, 2011, 12:50:13 PM »
I'm a little embarrassed. I didn't know there was a lesson for THAT. 

If there was a lesson on how to keep from losing my car keys I'd be all set.

Thanks guys.

Have you looked through the lessons?  Very good place for some of the more basic information if you haven't read through them.

Offline Betelgeuse

  • Member
  • Posts: 163
Re: Question for Newt
« Reply #6 on: June 15, 2011, 12:50:22 PM »
For the record, when you said "nuke" I thought there was some kind of "explosive" or damaging quality to them to the referenced drug  I didn't know you were abbreviating the word "nucleotide".

And that's why I couldn't find the answer I was looking for. I'm very aware of the difference between an NNRTI and NRTI.

Sorry for the trouble, guys.
« Last Edit: June 15, 2011, 12:56:09 PM by Betelgeuse »
04/19/11 - Diagnosed positive
04/29/11 - CD4 188 @ 12.5% / VL 18k
05/03/11 - CD4 171 @ unk% / VL 7k
06/04/11 - Start Truvada/Isentress
07/11/11 - CD4 not tested / VL UD
09/07/11 - CD4 252 @ unk% / VL UD

Offline newt

  • Member
  • Posts: 3,878
  • the one and original newt
Re: Question for Newt
« Reply #7 on: June 15, 2011, 03:18:41 PM »
There is no such thing as a dumb question about HIV treatment. I prefer saying nukes and non-nukes because it's easy to miss (include) an extra N in NNRTI (NRTI). << but doubtless am not consistent.

Hopefully your CD4 count will be above 200 soon and you can kick the Bactrim.

- matt
"The object is to be a well patient, not a good patient"

Offline J.R.E.

  • Member
  • Posts: 7,124
  • Joined Dec-2003 Living positive, since 1985.
Re: Question for Newt
« Reply #8 on: June 15, 2011, 03:26:10 PM »
Hello B,

Besides the lessons, here's a site that you may find helpful :"Glossary of Terms"


http://www.yourstoryyourscript.co.uk/glossary.html



Ray


Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 6/4/14,  t-cells are at 423, Viral load <40

 Current % is at 13% 

  
 62 years young.

Offline Betelgeuse

  • Member
  • Posts: 163
Re: Question for Newt
« Reply #9 on: June 15, 2011, 03:52:03 PM »
.
« Last Edit: June 15, 2011, 03:57:10 PM by Betelgeuse »
04/19/11 - Diagnosed positive
04/29/11 - CD4 188 @ 12.5% / VL 18k
05/03/11 - CD4 171 @ unk% / VL 7k
06/04/11 - Start Truvada/Isentress
07/11/11 - CD4 not tested / VL UD
09/07/11 - CD4 252 @ unk% / VL UD

Offline Ann

  • Administrator
  • Member
  • Posts: 28,140
  • It just is, OK?
    • Num is sum qui mentiar tibi?
Re: Question for Newt
« Reply #10 on: June 16, 2011, 09:18:35 AM »
I'm a little embarrassed. I didn't know there was a lesson for THAT. 

If there was a lesson on how to keep from losing my car keys I'd be all set.

Thanks guys.

I have the same problem with my glasses. I have to take them off to read so I'm forever misplacing them. It's difficult to find things when your vision is all skew-wiff. :D

For the record, when you said "nuke" I thought there was some kind of "explosive" or damaging quality to them to the referenced drug  I didn't know you were abbreviating the word "nucleotide".

hehehee... I had the same thought when I was first diagnosed and still learning.

Like Matt said, there is no such thing as a stupid question, so don't be embarrassed. Stupid answers, on the other hand.... ;D
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

 


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