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Author Topic: The Sustiva/Atripla Thread  (Read 44058 times)

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Offline Tonny2

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Re: The Sustiva/Atripla Thread
« Reply #150 on: August 02, 2015, 12:08:17 PM »


        ojo     Has anybody gotten a rash while taking sustiva and what did you do to solve the rash?....thanks for the feedbacks...hugs                               ojo

Offline Hedorian

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Re: The Sustiva/Atripla Thread
« Reply #151 on: September 22, 2015, 01:16:55 AM »
hallo there, just my experience:

started atripla yesterday: first night/day:

- No vivid dreams(dammit i was waiting for them somehow)
- little dizzyness after 1 hour taking it,than sleep.
-at wake up no problem,just feel slightly inappetent,but if its due to the pills or the stress of work im facing now i dont know.
-same for the sleeping,i wake up at 3:30 and had some problem fall asleep but again not sure if its the pills or the stress from job.

So..so far so good, in 2 weeks i have another liver/kidney tests and see on long term what happen.

Offline going_gone89

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Re: The Sustiva/Atripla Thread
« Reply #152 on: September 27, 2015, 01:10:04 PM »
Just started Stocrin last night, along with Truvada. Feelings of depersonalization and derealization were pretty obvious. Vivid dreams were not as bad as I expected, in fact I feel rested despite them.
Feeling anxious and shaky this morning, almost what it feels like a few hours after smoking pot? Funny considering one of the side effects I've read about is a false positive for pot in urine testing (which will make finding a job, im sure very enjoyable).

Besides that, I'm just happy I'm keeping my breakfast down. Which makes me curious, I know side effects vary greatly, but how soon after starting therapy do you experience those types of side effects? Nausea, vomiting, diarrhea, etc.
« Last Edit: September 27, 2015, 01:15:45 PM by going_gone89 »

Offline mlgoforth

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  • Michael Miguel Goforth devotee of Adi Da Samraj
    • Google Profile Michael Miguel Goforth
Re: The Sustiva/Atripla Thread
« Reply #153 on: October 02, 2015, 05:21:31 AM »
re; going_gone89
on: September 27, 2015, 01:10:04 PM

     "Just started Stocrin last night, along with Truvada. Feelings of depersonalization and derealization were pretty obvious. Vivid dreams were not as bad as I expected, in fact I feel rested despite them."
    [[ If your body can adapt this should go in a month or so, if it doesn't choose another HIV Cocktail.  Be careful don't get used to the depersonalization and derealization, I did that and it took 5 years to realize the drug was making me more and more and more crazy.]]
    "Besides that, I'm just happy I'm keeping my breakfast down. Which makes me curious, I know side effects vary greatly, but how soon after starting therapy do you experience those types of side effects? Nausea, vomiting, diarrhea, etc."
     [[For some it starts write away, some they never get those side effects. With Sustiva I had to take 1 1/2 dose Lopermide Hydrochloride (Imodium AD) every day to control diarrhea ]]
*Infected 1980, 35 years with HIV, Tested HIV+ 1987
*HIV Drugs 1998-2005 Viracept, 3TC, D4T
Changed to lessen metabolic syndrome (didn't work)
*2005-2010 Sustiva, 3TC, AZT
Changed to get normal sleep, brain function (working recovery taking years)
*2010-now Reyataz, Norvir, 3TC, AZT. I call it Reyavir(2) squared
*Virus undetectable 1998 on, CD4  1998=60(AIDS), 2015=500+
Side effects, 1998 on Metabolic Syndrome, 2003 on Extreme Fatigue gets worse @ year, 2005 on Neuropathy, 1998 on Buffalo Hump, 2014 on Wasting upper arms.
2013 Diabetic Ketoacidosis, well treated with Insulin.
Take Cannabis for Neuropathy, Lisnopril for blood pressure, Lipitor for Cholesterol, Testosterone (low for my age), Various supplements, Simple diet, no processed foods, lots of fermented food.

Offline Hedorian

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Re: The Sustiva/Atripla Thread
« Reply #154 on: October 10, 2015, 02:36:58 AM »
UPDATE on my Atripla trip.

Blood test kidney/liver perfect after 2 weeks treatment.

Dizzyness after taking it greatly reduced.

Heavy head on waking up at morning almost disappear.

had a mild rash on body at day 12 for just 1 day,gone in 3 days without taking any medicine.

No nausea,diarrea,psyco effect or whatever seen.

Sleep deep and good . ( no sweat no wake up no dreams).

Taking the pills on really empty stomach (4 hours last meal) for me helped than only 2 hours from.last meal

so i can say im lucky one with little to noone side effect.

Now i will check for the long term one (mental foggy..memory issue)

keep you posted

Offline RobbyR

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Re: The Sustiva/Atripla Thread
« Reply #155 on: October 26, 2015, 12:25:56 PM »
As someone who has taken this medication since 2010, I can say that for someone initially starting treatment or with a low cd4 it can be a great medication the first couple years I was on it overall got me very healthy has kept my numbers great, cd4 has stayed in the 700s. But the side effects have gotten cumulatively worse. First couple years in, problems with sleep. Insomnia, problems falling asleep. Then, severe panic attacks, anxiety, jittery, all this happened about two years in. Not sure if it takes that long to change your chemistry or something but it didn't happen overnight. It's kept me healthy but at quite a price in other ways. I went through a bad spell where I was suicidal and having terrible dreams.

I feel that Atripla has aggravated my anxiety to the point of having to be put on a lot of other meds to control the anxiety and insomnia. I've been put on Mirtazipine, Melatonin, and even blood pressure meds because of heart palpitations.

I've held out because I wanted to research other options but now after a week-long bad bout of insomnia, I can't take it any more and have told my doc I want to ditch it for good.

I suspect the dosing time at night plays a role in how bad it messes my sleep up.

Hopefully my new regimen I can take early in the day and so I'll sleep better. Lack of sleep literally makes you angry and insane.

If you can tolerate Sustiva great but I strongly suspect I can't, and am going to try either Stribild or Isentress/Truvada or another combination. I'll post again with updates.

My hope is that if I get a regimen I can tolerate better, I won't need all these other meds I hate feeling over medicated.
Atripla
2010-2015

Stribild
2015-

Offline terrymoore

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Re: The Sustiva/Atripla Thread
« Reply #156 on: October 28, 2015, 12:41:53 AM »
Greetings! I have waited a long time to read this post as i was on a different treatment, but now that i am UD, and my CD4 is good, my ID Doc raised this as an option yesterday.
I currently take 9 pills a day - Truvada x1 and Alluvia 4x2. She suggested i move to Atripla.
I inquired about alternative once-a-day regiments because of the harsh side-affects of Atripla, e.g. Complera, Stribild, or Trivicay (which i read about in this forum) and she was not really aware of them - probably because they are not available in Thailand. However, for Complera, she was familiar and knew the make-up which she said was Truvada + Rilpivirine.
She told me that compared to Atripla, which, according to her is made of Truvada + STocrin, and that Stocrin is known to have harsh side affects, but that they usually go away after a few weeks. She mentioned that the  Rilpivirine is known to be much milder than the Stocrin. The issue is, that taking the Atripla would mean taking 1 pill, where taking the Rilpivirine+Truvada combo would mean taking 2 pills.
My motives for changing treatments are as follows in order of priority:
1. Long term affects - i figure the less pills i take the less damage i will do to my body. Maybe i am wrong here, but it only seems logical to me - the less pills, the less damage i do (i know this isn't very scientific). Also, since i have a long way ahead of me (i hope at least 30 years!) i want to take something that has the least amount of damage to my body. I know the Alluvia (aka Kaltera) is bad for the long run, and i am now reading that Atripla is also not the kindest kid on the block. Which is why i am really considering the 2 pill regiment.
2. Routine and timezone - i prefer a once a day regiment at night - it is easier to remember, it is a single reminder of my unfortunate burden, but mainly b/c of of logistics - i travel west a lot and that means i have to wake up very early just to take my dose - sometimes i wake at 4AM to take my morning dose of Alluvia when in Europe. A once-per-day regiment at night will allow me to take that dose in the eve in Europe - so it would be much more convenient.
3. Travel logistics - each time i travel i must take a zillion pills with me. This means i calculate and recalculate and count and recount before each trip. It is a burden and a source of anxiety ("did i bring the right amount?"). Then the crossing of the borders with so many pills, in some countries that are not very HIV tolerant (e.g. Singapore until a few months ago denied HIV+ people from entering the country) can lead to a many questions if they get discovered. Imagine a 5 day business trip - today it is 45 pills in a carry on as opposed to 5 (or 10)!! the 45 makes me look like a smuggler hahaha!
4. Concealment - my condition is a well kept secret between me and my wife and my Doc (and you guys!). It is a challenge to hide 3 months worth of bottles today especially with 3 kids in the house. I figure, 3 (or 6) bottles is much easier to hide and disguise.

So, as of now i have a choice:
1. Stay on the 9 pills -PROs? "If it ain't broke don't fix it!" My body has adjusted, it seems to be doing wonders (CD4 over 1000 and UD) and i am used to the routine.
CONs - As i have mentioned above - travel, toxicity, concealment etc
2. Switch to Atripla - PROs - once a day? WOW! 1 PILL once a day?! Double WOW!!
CONs - just read the posts in this thread!
3. Switch to Truvada+Rilpivirine (aka Complera in it's 1 pill form) - PROs - once a day, supposedly less adverse side affects than Atripla.
CONs - 2 pills instead of one.
There is also a cost issue. Funny enough, option 3 is the cheapest - slightly cheaper than option 2 which is significantly cheaper than my current regiment.

I will continue with my current regiment for another 3 months, but i want to start researching my next step.

Comments, insights and sage advice will be much appreciated! Thanks!

Offline Jeff G

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Re: The Sustiva/Atripla Thread
« Reply #157 on: October 28, 2015, 07:10:54 AM »
If you have ever had a history of mental illness, depression or anxiety then Atripla is not the drug for you. Many regimens that are not single pill regimens can be taken once daily after you are stable and undetectable for awhile so don't get hung up on one pill treatments. 

Offline Wade

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Re: The Sustiva/Atripla Thread
« Reply #158 on: October 28, 2015, 09:28:24 AM »
That is an excellent point , I have been thinking
the same thing for quite a while.
What's one more pill ??? and little ore no side affects.
"Who put the pepper in the....Vaseline  ? " Coffee Butler

Offline RobbyR

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Re: The Sustiva/Atripla Thread
« Reply #159 on: October 28, 2015, 10:55:22 AM »
Yea I don't even care if I have to take 2-3 pills a day at this point, I've realized in the two days I've been off Atripla how much better I feel without it! Not panicky, anxious, or depressed at all! I feel clear headed, and calm! :)

Unfortunately I'll have to start taking it again just until next week when my appointment is then they'll switch me off. But I'm so ready to be done with this nasty pill for good. Any other regimen that doesn't cause full scale meltdowns will be an improvement!
Atripla
2010-2015

Stribild
2015-

Offline Wade

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Re: The Sustiva/Atripla Thread
« Reply #160 on: October 28, 2015, 11:48:10 AM »
Good to hear Robby !
"Who put the pepper in the....Vaseline  ? " Coffee Butler

Offline islandguy

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Re: The Sustiva/Atripla Thread
« Reply #161 on: January 11, 2016, 10:25:31 AM »
I am literally sitting here with the first Atripla pill in hand ready to start and now I'm somewhat terrified.  Jeez I'm panicky and haven't even started.

It's taken months to finally get all the blood work done, find an ID, and get a prescription that I've been so anticipating.  The box arrived today (insurance will only do mail order but on the other hand I'm not even paying a co-pay) so I thought I'd browse through here to see what kind of side effects I might be expecting and I certainly wasn't expecting the nightmares (some literal) that I've been reading about here.

I'm just wondering if all the side effects I'm reading about really only happen to a small percentage of people who have chosen this thread to talk about and there are thousands more who take it with no problems so no reason to come here?

I've been so looking forward to finally getting started on meds that it's a real bummer to now read about what could happen.

I guess there's no harm in giving it a try, monitoring my behavior, and hoping for the best or an alternative down the line. 

So here goes.  Gulp.  First step towards the rest of my life.

Offline terrymoore

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Re: The Sustiva/Atripla Thread
« Reply #162 on: January 11, 2016, 11:55:32 AM »
Hi Islandguy,
I also just took my first Atripla tonight and wondering what side affects i will feel. My doc gave me some great advice. He said, some people have bad reactions, MOST people have mild reactions and some have none. He continued to explain that there is no "formula" as to whom will feel what. So, as he put it," you never know unless you try!".
2 hours into it and feel normal. Hoping i stay this way. Good luck!

Offline islandguy

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Re: The Sustiva/Atripla Thread
« Reply #163 on: January 11, 2016, 11:05:33 PM »
Terry no side effects that I've felt over 2 days but I take it at night so I may be sleeping thru anything. I was thinking about it today and I'm pretty happy to be starting it. It's proven to work, and work fairly quickly. Once I'm UD I can consider something else and there will no doubt be something even better coming along. Hope you're doing good too.

Offline Jeff G

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Re: The Sustiva/Atripla Thread
« Reply #164 on: January 12, 2016, 07:11:38 AM »
Hey Guys, Please dont be afraid to take Atripla with any more or less concern than you would any other med. The point of this thread was to make sure people were vigilant and on the lookout for any possible side effects which you should do for any medication.

Offline bocker3

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Re: The Sustiva/Atripla Thread
« Reply #165 on: January 12, 2016, 07:55:05 AM »
While Atripla is not for everyone (which could probably be said about almost ANY drug), I have been taking Atripla (or its components, as Atripla didn't exist when I started) for over 10 years.  The only "side effect" that I have are the vivid dreams still come around from time to time -- but over all this time only a handful have been "unpleasant".  Oh, I suppose that the tenofovir may be responsible for some gas at times, but then, I could have inherited that from my father too....   :o

So, be on the lookout for any side effects, but don't panic -- many, many people take this drug without any negative impacts.

Good health to you!!
Mike
Atripla - Started 12/05
Reyataz/Norvir - Added 6/06
Labs - Pre-Meds
Sep05 T=350/25% VL98,559
Nov05 288/18%  47,564
Current Labs
May2015 969/28% <20

Offline terrymoore

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Re: The Sustiva/Atripla Thread
« Reply #166 on: January 12, 2016, 12:03:35 PM »
So, 24hours into this and the affects are.... interesting  :).
I take the pill at 10 pm. Last night I ate about 30 minutes before (tonight i didn`t). At about 2 hours  or so i start to get a bit "foggy" - like i smoked some old weed. Face gets a little hot and ears sorta ring a bit -nothing major.
I slept well, although i did have weird dreams about taking my old morning dose of 4 Aluvia through a nerf-gun (oh well, dreams!), and suddenly realising i shouldn`t be "shooting" those 4 pills into my mouth since i only take my 1 pill at night. This dream recurred 3 or 4 times in various versions (always the nerf gun..).
i woke very groggy. And then i was very foggy - hard to concentrate, hard to multitask, slightly "woozy", and my coffee tasted weird.
I decided NOT to go to the gym feeling that way. i hung around and worked for a few more hours and then finally drove to a meeting, and felt completely normal from that point on. So something like hour 2-12 after taking the pill is when i am in "high" mode. I probably should sleep longer. I hope this wares off by next week because i have a business trip and i can`t be "high" for the first few hours! hahahaha. Besides that, my stomach is noticeably MUCH better. I`m liking this 1 pill business! Will keep you posted.

Offline terrymoore

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Re: The Sustiva/Atripla Thread
« Reply #167 on: January 12, 2016, 07:53:45 PM »
quick update - i woke up this morning (6:30 after the last post) and feel fine. Slight "tin" taste, no "fog" like yesterday, no dizziness, definitely multi-tasking - i`m on fire here shooting out the emails and managing a few crisis. So all good!
No dreams about nerf-guns, although i did have a great dream about opening up a grocery store in the 1930`s - it was like an entire movie!
Besides that, stomach is a zillion times better!
Atripla I LOVE YOU!
Gents, thanks for the words of support - it helped in making this decision.
Good day to all!

Offline RobbSC

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2 years on Atripla
« Reply #168 on: January 14, 2016, 01:39:37 PM »
I am going on 2 years on Atripla. I honestly don't have any real issues with the meds except for the occasional wild dreams - many aren't all that bad though. I am a bit groggy in the morning and it takes me a while to really get moving. I spoke to my doctor about the new TAF version but he prefers I stay on my current regime since it is working so well. Since then maybe I am making up more side effects like lack of focus, reduced energy, etc...I really don't know that the meds cause them or if it is me reading about new drugs and wanting to be on them for kidney and bone issues long term.
For now though I will press forward with Atripla until side effects are obvious.

Offline Tonny2

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Re: The Sustiva/Atripla Thread
« Reply #169 on: January 15, 2016, 02:35:21 PM »


           ojo       Hi everyone...I took sustiva for five years, I remember having just three or four nights with vivid dreams, after that, I didn't feel anything, tho, everybody reacts differently to the meds,I still think sustiva is a good med, I stopped it because I had to switch treatment..the only way to know if a medication is going to be good for you is trying it and see what happens, fortunally, sustiva is not like abacavir, which, now, you have to be checkedfor a adverse reaction before you take it...hugs          ojo

Offline terrymoore

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Re: The Sustiva/Atripla Thread
« Reply #170 on: January 22, 2016, 11:42:18 AM »
Hi,
Looking for some advice here. I have recently started Atripla and so far the side affects have been mild. i have  had a few cases of that "drunk" feeling, and i guess it happened when i ate late close to when i took my dosage, or when i drank.
Normally though, i just go to bed an hour or 2 after taking my meds at 10pm.
My problem is that i must fly to Europe which means i will need to take the pill at 5pm (i live in Asia).
I worry because it means i will have to endure a good 5 hours before getting to bed, and a big part of that will be with colleagues from work or family.
I also will have to drive.
Should i just delay taking the pill by 5 hours the first day (compensating the time difference) so that i take the pill at bedtime while in Europe? The trip will be for 8 nights.


Offline Jeff G

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Re: The Sustiva/Atripla Thread
« Reply #171 on: January 22, 2016, 11:45:20 AM »
Hi,
Looking for some advice here. I have recently started Atripla and so far the side affects have been mild. i have  had a few cases of that "drunk" feeling, and i guess it happened when i ate late close to when i took my dosage, or when i drank.
Normally though, i just go to bed an hour or 2 after taking my meds at 10pm.
My problem is that i must fly to Europe which means i will need to take the pill at 5pm (i live in Asia).
I worry because it means i will have to endure a good 5 hours before getting to bed, and a big part of that will be with colleagues from work or family.
I also will have to drive.
Should i just delay taking the pill by 5 hours the first day (compensating the time difference) so that i take the pill at bedtime while in Europe? The trip will be for 8 nights.



Atripla has a long half life and stays in your system a long time it would be ok to just take before bed or even to skip one dose to get back on schedule. It wont hurt a thing.

Offline terrymoore

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Re: The Sustiva/Atripla Thread
« Reply #172 on: January 22, 2016, 08:28:41 PM »
Thanks for the. quick reply JeffG! As a follow-up, does hat mean that i won`t screw things up by switching back to the normal schedule 8 days later?

Offline Jeff G

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Re: The Sustiva/Atripla Thread
« Reply #173 on: January 22, 2016, 08:56:24 PM »
Thanks for the. quick reply JeffG! As a follow-up, does hat mean that i won`t screw things up by switching back to the normal schedule 8 days later?

No it wont hurt a thing .

Offline Archi

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Re: The Sustiva/Atripla Thread
« Reply #174 on: January 25, 2016, 01:14:41 PM »
I have Atripla 11 days. Do not fill nothing wrong. Doctor told can't eat 2-3 hours before pil  . How long need can't eat after this pil ?  Can't eat because why ?  Samtiems I'm we're hungry at this a few hours , or go out with friends.  And all ways take treatment at 10.30 pm.

Offline Tonny2

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Re: The Sustiva/Atripla Thread
« Reply #175 on: January 25, 2016, 02:15:09 PM »
I have Atripla 11 days. Do not fill nothing wrong. Doctor told can't eat 2-3 hours before pil  . How long need can't eat after this pil ?  Can't eat because why ?  Samtiems I'm we're hungry at this a few hours , or go out with friends.  And all ways take treatment at 10.30 pm.

           ojo        Hello Archi... some people get less side effects on an empty stomoch, but you can try it with food too, I used to take my med with food and never had any problems, some friend of mine, take it with food too, one even take it in the morning, its easier for him that way...why don't you try take it with food and see how you feel, most likely you will not feel anything because you haven't noticed any side effects...so, the only way you will know how you will feel taking it with food, its trying, I think you will be fine...hugs        ojo
Ah!!!, then, you can go out with your friends

Offline Jeff G

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Re: The Sustiva/Atripla Thread
« Reply #176 on: January 25, 2016, 06:47:16 PM »
It wont hurt the effectiveness of Atripla but a fatty meal can increase the possibility that you will have the CNS issues listed as possible side efects like vivid dreams but the med still works great no matter what your diet is.

Offline Tonny2

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Re: The Sustiva/Atripla Thread
« Reply #177 on: January 25, 2016, 09:31:18 PM »


           ojo         Hello again Archi, I agree with Jeff, food might increase your side effects, but  still think you should try it, I did it, and I just had three or four nights of vivid dreams, that was it, but, I think, since you haven't had any side effects, you will be fine...best of luck...hugs                                                                     ojo

Offline Archi

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Re: The Sustiva/Atripla Thread
« Reply #178 on: January 25, 2016, 11:03:18 PM »
Thank you for answer. I'm hope new therapy be better very soon. And we be negative again :)

Offline terrymoore

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Re: The Sustiva/Atripla Thread
« Reply #179 on: Yesterday at 01:57:52 AM »
Hi,
It has been around 3 weeks since my last post in this thread and my opinion re Atripla has changed  - for ME. I have noticed that i am waking more and more foggy, less capable of being "sharp", and easily confused by things that should be fairly simple. It is hard to explain. I have also been a bit moody. Sometimes i just get "snappy" at my wife, or impatient. In general i feel down. My wife thinks it is all in my mind. Of course this makes me upset especially since she is right - the problem i am feeling is IN MY MIND!! :-)
I thought i would sweat it out for at least another month, but i have decided today to see the doc tomorrow and ask him to switch to something else. In Thailand we do not have any other 1 pill regiments, but we do have 2 pill regiments (Complera-like) and i think that is what i will choose. I can`t stand losing what i have always thought was my strongest asset - my sharp, quick, on-top-of-things mind. Luckily i didn`t buy that 6 month supply yet!
I hope i am not being to rash with my decision (maybe the Atripla is to blame for this too!).
Will keep you posted.

Offline Jeff G

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Re: The Sustiva/Atripla Thread
« Reply #180 on: Yesterday at 10:14:16 AM »
Hi,
It has been around 3 weeks since my last post in this thread and my opinion re Atripla has changed  - for ME. I have noticed that i am waking more and more foggy, less capable of being "sharp", and easily confused by things that should be fairly simple. It is hard to explain. I have also been a bit moody. Sometimes i just get "snappy" at my wife, or impatient. In general i feel down. My wife thinks it is all in my mind. Of course this makes me upset especially since she is right - the problem i am feeling is IN MY MIND!! :-)
I thought i would sweat it out for at least another month, but i have decided today to see the doc tomorrow and ask him to switch to something else. In Thailand we do not have any other 1 pill regiments, but we do have 2 pill regiments (Complera-like) and i think that is what i will choose. I can`t stand losing what i have always thought was my strongest asset - my sharp, quick, on-top-of-things mind. Luckily i didn`t buy that 6 month supply yet!
I hope i am not being to rash with my decision (maybe the Atripla is to blame for this too!).
Will keep you posted.

If its the meds and it sounds like it is, you will feel better in a day or two after a med change and then you will know. Its hard to get people to realize it takes abut 5 seconds more of their time to take another pill so getting hung up on a one pill a day regimen is very limiting Best of luck !

 


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