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Author Topic: Long-Term Use Of HAART Actually Protects The Liver?  (Read 751 times)

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Offline tednlou2

  • Member
  • Posts: 4,770
Long-Term Use Of HAART Actually Protects The Liver?
« on: April 10, 2011, 03:08:12 AM »
I was going to put this in Research News, but I thought Living was a better place, since many of us scared about meds usually worry about the effects to the liver when deciding when to start.  I already wonder whether having HIV means I have to be more careful with drugs containing acetominophen--well, most meds for that matter.  I did not know liver disease is the number one cause of death for people with HIV.  Would the normal liver function tests pick up this kind of liver damage?  From this article, it seems ARVs are the best way to protect the liver. 

http://www.aidsmeds.com/articles/hiv_liver_fibrosis_1667_20194.shtml

Offline pozoz

  • Member
  • Posts: 70
Re: Long-Term Use Of HAART Actually Protects The Liver?
« Reply #1 on: April 10, 2011, 03:55:54 AM »
Good article.

Was surprised to see Videx, Zerit, and Hivid mentioned for toxicity, and not Nevarapine.. which seems to have a reputation for hepatotoxicity that can be fatal and/or irreversible in some people. (It's on the leaflet of Nevarapine prescriptions) Shows how important monitoring liver health is for all pozzies whether on meds or not. Was also surprised that liver disease in the #1 cause of death in HIV+ persons.

I think a lot of people underestimate the toxicity of OTC pain relievers such as Tylenol/Panadol, and excessive alcohol consumption on our already taxed out livers.
Seroconverted Aug 2008
Tested Pos      May 2009
May 09 CD4 544 19%   VL 22K
Aug 09 CD4 514  19% VL 25K
Dec 09 CD4 510  20% VL 32K
June10 CD4 502  20% VL 36K
July 5th,10 Start Truvada  Reyataz Norvir July 30  CD4 360  21% VL 339
Oct  22 CD4 459  27% VL 191
Jan 2011CD4 561 33% VL U/D <40
Feb  Add Verimune lead in dose to start switch to Verimune/Truvada  
Mar 17 Viramune x2 + Truvada. Stop PIs   
Apr 29     CD4 528 33% VL U/D
July 2011 CD4 440  %?  VL U/D
Sept 2011CD4 620  %?   VL U/D
Dec 2011 CD4 531 31% VL 224
Jan 2012  CD4 576 36% VL U/D
May 2012 CD4 504 36% U/D (start Viramune XR
July 2012 576 (36%) (test request due to XR issues)
Feb  2013 629  (? %) U/D
July  2013 608 38%.   U/D
Jan  14.    576  36%.   UD

Offline buginme2

  • Member
  • Posts: 2,834
Re: Long-Term Use Of HAART Actually Protects The Liver?
« Reply #2 on: April 11, 2011, 10:29:52 PM »
I actually got diagnosed with HIV because I was having issues with my liver.    My liver enzyme tests were elevated and I was referred to a GI doctor after my regular doctor could not find a reason why they were elevated (all hep tests were negative and I was vaccinated for a and b). The GI doctor eventually diagnosed HIV after a year of searching for what was causing the liver problems.   Since I have been on HIV meds all my liver tests have returned to normal.  In my very unscientific method I am convinced HIV has a negative effect on the liver. 

 


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