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Author Topic: Why do some people NOT become HIV positive?  (Read 1914 times)

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Offline Zohar

  • Member
  • Posts: 249
Why do some people NOT become HIV positive?
« on: March 05, 2011, 02:52:57 PM »
I was just reading a post in an HIV forum on a gay website where someone said:

''I had been sleeping with my ex for 3 months bareback before I found out I was positive. I assumed I had given it to him but he is completely negative and I always topped.''


This isn't the first time I've heard of risky behaviour not leading to HIV infection, and just got me thinking why some people can have a lot of exposure to the virus without it taking hold, and yet tales of people becoming infected after a very occasional slip-up with condoms aren't that difficult to come across either.

I've heard of prostitutes in Africa (Uganda, I think) who seem to have acquired  some sort of immunity, but is anyone aware of any studies, or have any theories, about what causes some people in the general population to be seemingly more prone to HIV infection than others?
''Poor is the man whose pleasures depend on the permission of another.''

Offline Matts

  • Member
  • Posts: 223
Re: Why do some people NOT become HIV positive?
« Reply #1 on: March 05, 2011, 04:05:56 PM »
"It is possible that a person with the CCR5-Δ32 receptor allele will not be infected with HIV R5 strains. Several commercial testing companies offer tests for CCR5-Δ32.
The allele has a negative effect upon T cell function, but appears to protect against smallpox and HIV."

More:
http://en.wikipedia.org/wiki/CCR5
tivicay/kivexa

 


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