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Author Topic: Any Immuno-Suppresive components in Atripla ?  (Read 2208 times)

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Offline sam66

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Any Immuno-Suppresive components in Atripla ?
« on: December 06, 2010, 06:47:10 AM »
   
            Hi,
                 This feels like a strange question to ask, does anyone have the answer, I'm going to ask for a
            appointment with my clinical pharmacist it would be usefull to have this information.

           Does Atripla contain immuno-suppresive components ?

            sam
december 2007 diagnosed +ve ,

Offline Hellraiser

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #1 on: December 06, 2010, 11:51:55 AM »
I don't know if you would call it immunosuppressive, but Atripla NNRTIs which are known to artificially keep your CD4 just a little lower than it normally would be.  It's supposed to be around 50-100 CD4.  Is this what you're asking about?

Offline sam66

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #2 on: December 06, 2010, 01:10:07 PM »
          Hellraiser

                       I have been contacted by my pharmacist regarding a supplement I have been taking, citing
          possible interaction with immuno-suppresive medication.

          I'm Atripla and Lipid lowering meds. I didn't think it could possibly be the statins
december 2007 diagnosed +ve ,

Offline Inchlingblue

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #3 on: December 06, 2010, 06:49:32 PM »
          Hellraiser

                       I have been contacted by my pharmacist regarding a supplement I have been taking, citing
          possible interaction with immuno-suppresive medication.

          I'm Atripla and Lipid lowering meds. I didn't think it could possibly be the statins


Have you tried using the Check Your Meds feature on here?

LINK:


http://www.aidsmeds.com/cmm/

Offline Ann

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #4 on: December 07, 2010, 07:54:01 AM »
Sam, as this information came from your pharmacist, perhaps you need to discuss this with him to find out exactly what he's talking about and why he sent you this warning.
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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline sam66

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #5 on: December 07, 2010, 08:21:45 AM »
      Yes good idea Ann
                               I'm going to see my nurse this week, will raise the matter then.
                             
                               sam
december 2007 diagnosed +ve ,

Offline Inchlingblue

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #6 on: December 07, 2010, 09:17:45 AM »
Asrtragalus has been found to stimulate the immune system so it stands to reason that it would interact with a medication designed to do the opposite, i.e. be immunosuppresive.

I don't think anything in the HIV meds would be immunosuppresive but I don't know for sure. At any rate, I did take astragalus before starting meds in order to help stimulate my immune system but once I started meds I felt it was no longer necessary.
« Last Edit: December 07, 2010, 09:20:23 AM by Inchlingblue »

Offline sam66

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #7 on: December 07, 2010, 10:11:01 AM »
     Yes, thanks Inch,
                               I guess they dont have any data on this combination, may be best not to take any
               chances
december 2007 diagnosed +ve ,

Offline Ann

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #8 on: December 07, 2010, 10:46:42 AM »
      Yes good idea Ann
                               I'm going to see my nurse this week, will raise the matter then.
                             
                               sam

But if the original information came from your pharmacist, why ask your nurse? He or she may not know. It's the pharmacist's job to know about these kinds of interactions, so he would be the appropriate person to go to for the best answer.

If your pharmacist contacted you by a snail-mail letter or rang you on the telephone, ring him and ask. If he contacted you via email, respond to the email and ask your questions.

In a case like this, it really is best to go to the original source of the warning.
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline sam66

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #9 on: December 07, 2010, 11:05:50 AM »

           I meant to say I will ask to see the pharmacist after the nurse,  Ann
december 2007 diagnosed +ve ,

Offline Ann

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #10 on: December 07, 2010, 11:11:49 AM »
           I meant to say I will ask to see the pharmacist after the nurse,  Ann

Glad to hear it! :)
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline Tempeboy

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #11 on: December 07, 2010, 08:18:29 PM »
Hey Sam,

The only immunosuppressive issues relating to Efavirenz are it's propensity to cause Vitamin D3 hypovitaminosis (Vitamin D's are important in the manufacture of CD4 and other cells integral to iimmunity).  Ask your doctor or nurse to check your Vitamin D levels in your next blood tests - if they are low supplements may be suggested.

Also, starting any combination can lead to Immune Reconstitution Sydrome - as your immune system regains it's former strength and function it can 'attack' infections that have being lying dormant.  The severity of this can vary and is more likely to occur in people with lower CD4 counts when commencing treatment.

you should be fine, take care
Roughly roundabout somewhere in the eighteenth or nineteenth century, Sodomite begat Homosexual out of moral, medical and legal models, bequeathing him Identity, who inbred with Nuclear Family and Industrialism to spawn Homophobia.

Dean Kiley

Offline sam66

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #12 on: December 08, 2010, 07:58:15 AM »
   Thanks Tempe

                      You are correct, they took blood 4 weeks ago, I'm pretty sure they said will check Vitamin D
   level,  will know in next couple of days.

   sam
                     
december 2007 diagnosed +ve ,

Offline Tempeboy

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Re: Any Immuno-Suppresive components in Atripla ?
« Reply #13 on: December 08, 2010, 07:15:11 PM »
Fab, you obviously have a great clinical team.

All the best, hope the combo is working for you - I am assuming you have started treatment.

Here is a link to foods that are rich in Vitamin D (and lots of other nutritional information) - http://www.healthalternatives2000.com/vitamins-nutrition-chart.html

take care

tb

PS - did your pharmacist explain her or his comment?
Roughly roundabout somewhere in the eighteenth or nineteenth century, Sodomite begat Homosexual out of moral, medical and legal models, bequeathing him Identity, who inbred with Nuclear Family and Industrialism to spawn Homophobia.

Dean Kiley

 


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