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Author Topic: A second virus eradicated  (Read 4365 times)

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Offline Assurbanipal

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A second virus eradicated
« on: October 17, 2010, 08:27:43 PM »
In only the second elimination of a disease in history, rinderpest — a virus that used to kill cattle by the millions, leading to famine and death among humans — has been declared wiped off the face of the earth.

http://www.nytimes.com/2010/10/16/science/16pest.html?hpw

Smallpox 1980
Rinderpest 2010
5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%

Offline Rev. Moon

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Re: A second virus eradicated
« Reply #1 on: October 17, 2010, 08:31:56 PM »
Pretty cool.  Thanks for sharing, Assurb.
"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

Offline Hellraiser

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Re: A second virus eradicated
« Reply #2 on: October 18, 2010, 02:22:38 AM »
This is very interesting stuff.  If you want to read a fantastic book about the eradication of smallpox (and the state of the virus today) I would suggest "Demon in the Freezer", which was a very good read.

Offline Assurbanipal

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Re: A second virus eradicated
« Reply #3 on: June 27, 2011, 05:08:11 PM »
Official ceremony is tomorrow!

http://www.nytimes.com/2011/06/28/health/28rinderpest.html

and it only cost $5 Billion (about 2/3rds the cost of a highway bridge over the Hudson).

5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%

Offline Hellraiser

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Re: A second virus eradicated
« Reply #4 on: June 27, 2011, 05:49:48 PM »
Official ceremony is tomorrow!

http://www.nytimes.com/2011/06/28/health/28rinderpest.html

and it only cost $5 Billion (about 2/3rds the cost of a highway bridge over the Hudson).



After having posted in this a while back I completely forgot about this thread.  The title made me think we had a second Timothy Brown on our hands.

Offline LM

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Re: A second virus eradicated
« Reply #5 on: June 27, 2011, 06:44:07 PM »
I hope I live long enough to see HIV added to this list.

Online mecch

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Re: A second virus eradicated
« Reply #6 on: June 27, 2011, 06:54:53 PM »
I hope I live long enough to see HIV added to this list.
How old are you?  I doubt HIV will be eradicated from the Earth.  Maybe a cure for those infected.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline dpb

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Re: A second virus eradicated
« Reply #7 on: June 27, 2011, 07:00:47 PM »
I hope I live long enough to see HIV added to this list.

I second that.  

How old are you?  I doubt HIV will be eradicated from the Earth.  Maybe a cure for those infected.

What's wrong with having hope?  I believe in being realistic and grounded, but why not dream big?  Why not hope for a better world? 

There are actually two ongoing eradication attempts sanctioned by the World Health Organization:  Dracunculiasis (Guinea worm disease) and Poliomyelitis.  I know that the Carter Center and the Bill & Melinda Gates Foundation are both heavily investing in those efforts.

This is the type of thing that really makes me want to get involved.
Date        CD4    %    VL
1/15/11    Diagnosed
3/1/11    525    18    168,518
5/12/11    558    16    331,791
5/16/11    Started Atripla
5/31/11    NA    NA    1,200
6/15/11    721    21    330
7/15/11    649    23    231
8/15/11    569    25    UD
11/17/11  752    26    UD
3/1/12    634    27    UD
7/2/12    594    26    UD
2/13       676    30    UD
9/13       662    31    UD

Offline LM

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Re: A second virus eradicated
« Reply #8 on: June 27, 2011, 07:05:49 PM »
I'm 26.

I sure hope for a cure, especially in the next 10, 20 years, like most predict. If not, well, tough luck. If like some say, that I can expect a relatively normal life expectancy, even with HIV, then I should live what, more 40, 50 years? If nothing goes wrong on the way, of course. So I guess I can dream of HIV eradication from the planet in this time frame.  :)

Offline buginme2

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Re: A second virus eradicated
« Reply #9 on: June 27, 2011, 07:27:12 PM »
And all the cows of the world breathe a sigh of relief.

Online mecch

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Re: A second virus eradicated
« Reply #10 on: June 27, 2011, 07:42:55 PM »
I am hopeful for a cure.
I don't know enough about epidemiology to understand what would be required to eradicate the virus from the face of the earth.  Apples and oranges.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline Hellraiser

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Re: A second virus eradicated
« Reply #11 on: June 28, 2011, 12:56:45 AM »
The best part of this is we offed the virus that decimates cattle....so that we can kill them ourselves.

Offline spacebarsux

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Re: A second virus eradicated
« Reply #12 on: June 28, 2011, 04:01:27 AM »
I hope I live long enough to see HIV added to this list.

I hope so too, but I don't really expect it to happen in my life time. Hope I am wrong.

I am little more optimistic of a complete cure (complete eradication of HIV from my body), but don't really know what to expect in my life time.

I am most optimistic of some sort of 'functional cure', I do sort of expect that to happen in my life time.

I am 28.
« Last Edit: June 28, 2011, 04:03:48 AM by spacebarsux »
Infected-  2005 or early 2006; Diagnosed- Jan 28th, 2011; Feb '11- CD4 754 @34%, VL- 39K; July '11- CD4 907@26%,  VL-81K; Feb '12- CD4 713 @31%, VL- 41K, Nov '12- CD4- 827@31%

Offline Assurbanipal

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Re: A second virus eradicated
« Reply #13 on: June 28, 2011, 08:10:01 AM »
How old are you?  I doubt HIV will be eradicated from the Earth.  Maybe a cure for those infected.

I posted this is because it shows how the world is becoming better organized around eradication efforts, once there is a cure.

Eradication of smallpox has happened, rinderpest as well, and guinea worm and polio are in process  as dpb pointed out.  That international organizations are getting better and better at the logistics of fighting and eradicating disease is a source of long term, measured, steady optimism that we will some day eradicate HIV.

But first we need a cure.

And it has to be the right type of cure -- something that can be administered in the field (like pills). 

But then it will be feasible to start thinking about eradication -- on a long term timetable.  It will take fear (of which there is plenty) hope, activism, organization and dollars (lots of them -- although perhaps less than one might think compared to other values).  But we humans are developing the skills and capabilities to do that.

Sometimes this forum suffers from a certain breathless, blind and perhaps not very well informed optimism.  But blind pessimism is no better.  The ability to target a disease and eradicate it is a uniquely modern artifact of sceince, and one where our capability appears to be accelerating.
5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%

 


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