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Author Topic: time of day for meds  (Read 2187 times)

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Offline debsd222

  • Member
  • Posts: 69
time of day for meds
« on: October 01, 2010, 08:14:48 PM »
Hi all... I have been taking reyataz, truvada and norvir for about 2 years. Someone told me they can keep you awake so I switched to taking them in the am (Im a terrible insomniac) but I wonder if they are lending to some of my difficulty concentrating or memory lapses during the day. Has anyone heard of this combo causing either the insomnia or daytime fuzziness?  I checked my "side effects" paperwork for the drugs but they are pages and pages. thanks, Deb
April 08 3 month bout w/ shingles, ongoing nerve pain
Dec 08 pos  cd4 200 %8  VL 18,000
Feb 09 started sustiva, truvada -allergic to sustiva, hospital 4 days.
March 09 started truvada, reyataz and norvir
March 09  cd4 279  % 12 VL 10,000
April 09 cd4 327  %12  VL 300
Aug 09 cd4 392  %16  Vl undetectable
Dec 09 hospital pneumonia 6 days
Dec 09 cd4 462  %20  VL undetectable
Mar 10 cd4 629 27% VL undetectable
July 9, 2010 cd4 505  21% VL undetectable
Oct 2010 cd4 689  22%  VL 64
Nov 2010  cd4689  22%  VL  UD
May 2013 cd4 759. 29%. VL. UD

Offline pozoz

  • Member
  • Posts: 70
Re: time of day for meds
« Reply #1 on: October 02, 2010, 06:40:31 AM »
Hi Deb,

I also take this combo.

Sometimes I wake up a bit groggy and lightheaded ( I have mine after dinner)

A strong cup of coffee or two seems to help get me going...

I do weird shifts, 12 hrs 7 days then 12 hrs 7 nights for 14 days straight then have 7 off. The night shifts are difficult at times (hell, so are the days sometimes! LOL) but I get by with the occasional red bull and try to get at least 7 hrs of sleep which is very hard sometimes...

Have not thought much about switching to the morning instead of night, let us know how the switch goes and good luck!!!....

Peace....

(edited for spelling)
« Last Edit: October 02, 2010, 06:42:29 AM by pozoz »
Seroconverted Aug 2008
Tested Pos      May 2009
May 09 CD4 544 19%   VL 22K
Aug 09 CD4 514  19% VL 25K
Dec 09 CD4 510  20% VL 32K
June10 CD4 502  20% VL 36K
July 5th,10 Start Truvada  Reyataz Norvir July 30  CD4 360  21% VL 339
Oct  22 CD4 459  27% VL 191
Jan 2011CD4 561 33% VL U/D <40
Feb  Add Verimune lead in dose to start switch to Verimune/Truvada  
Mar 17 Viramune x2 + Truvada. Stop PIs   
Apr 29     CD4 528 33% VL U/D
July 2011 CD4 440  %?  VL U/D
Sept 2011CD4 620  %?   VL U/D
Dec 2011 CD4 531 31% VL 224
Jan 2012  CD4 576 36% VL U/D
May 2012 CD4 504 36% U/D (start Viramune XR
July 2012 576 (36%) (test request due to XR issues)
Feb  2013 629  (? %) U/D
July  2013 608 38%.   U/D
Jan  14.    576  36%.   UD

Offline debsd222

  • Member
  • Posts: 69
Re: time of day for meds
« Reply #2 on: October 02, 2010, 10:34:04 AM »
pozoz, thats a crazy schedule- are you a firefighter?
April 08 3 month bout w/ shingles, ongoing nerve pain
Dec 08 pos  cd4 200 %8  VL 18,000
Feb 09 started sustiva, truvada -allergic to sustiva, hospital 4 days.
March 09 started truvada, reyataz and norvir
March 09  cd4 279  % 12 VL 10,000
April 09 cd4 327  %12  VL 300
Aug 09 cd4 392  %16  Vl undetectable
Dec 09 hospital pneumonia 6 days
Dec 09 cd4 462  %20  VL undetectable
Mar 10 cd4 629 27% VL undetectable
July 9, 2010 cd4 505  21% VL undetectable
Oct 2010 cd4 689  22%  VL 64
Nov 2010  cd4689  22%  VL  UD
May 2013 cd4 759. 29%. VL. UD

Offline eric48

  • Member
  • Posts: 1,179
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
Re: time of day for meds
« Reply #3 on: October 02, 2010, 07:09:35 PM »
Some coincidence !

you're asking this question the very same day I am shifting my timing (on a different combo (viramune+Epzicom)) because
I was initially taking the Epzicom (Kivexa) at 7 PM. 2 weeks after shifting to 7 AM (because my doc suggested that if I felt it keeps me awake, I should shift)
 I started having a mild to severe tension in the jaw that would not go away. I am shifting back to the initial timing.
The experiment is not yet conclusive but I will give it some more weeks (the tension in the jaw, mimicking stress) triggered 2 weeks after timing change

I'll report in my thread on viramune+Epzicom. But , yes, at this time I suspect timing can have some influence.

Cheers Eric
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 2 months

Offline debsd222

  • Member
  • Posts: 69
Re: time of day for meds
« Reply #4 on: October 03, 2010, 09:10:23 PM »
Thanks, guys...Im going to give it a try starting tomorrow. Ill keep ya posted.
April 08 3 month bout w/ shingles, ongoing nerve pain
Dec 08 pos  cd4 200 %8  VL 18,000
Feb 09 started sustiva, truvada -allergic to sustiva, hospital 4 days.
March 09 started truvada, reyataz and norvir
March 09  cd4 279  % 12 VL 10,000
April 09 cd4 327  %12  VL 300
Aug 09 cd4 392  %16  Vl undetectable
Dec 09 hospital pneumonia 6 days
Dec 09 cd4 462  %20  VL undetectable
Mar 10 cd4 629 27% VL undetectable
July 9, 2010 cd4 505  21% VL undetectable
Oct 2010 cd4 689  22%  VL 64
Nov 2010  cd4689  22%  VL  UD
May 2013 cd4 759. 29%. VL. UD

Offline chguy78

  • Member
  • Posts: 67
Re: time of day for meds
« Reply #5 on: October 09, 2010, 07:22:06 PM »
Has anyone heard of this combo causing either the insomnia or daytime fuzziness? 

I've taken Truvada+boosted Reyataz in the mornings for about 18 months now and do not experience any noticeable side effects such as insomnia or "daytime fuzziness."  I chose to take them in the morning just because my morning schedule is much more predictable than my evening one.
01/11: CD4=753 (36%), VL=Undetectable
07/10: CD4=531 (33%), VL=Undetectable
04/10: CD4=746 (33%), VL=Undetectable
01/10: CD4=566 (35%), VL=Undetectable
10/09: CD4=436 (31%), VL=405
07/09: CD4=631 (27%), VL=847
06/09: Started: Truvada, Reyataz, Norvir
05/09: CD4=426 (28%), VL=38,300
04/09: Positive; CD4=466 (28%), VL=39,700
10/08: Negative

 


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