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Author Topic: Eat Me, Bitches  (Read 5929 times)

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Offline Matty the Damned

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Eat Me, Bitches
« on: August 24, 2010, 10:14:14 AM »
Been on my new regimen (Raltegravir/Norvir/Truvada/Prezista) for a month or so.

Viral Load down from 96,000 to 496.

CD4 up from 12% to 14% (it's like in the 200s)

Oh yeah. :)

I keep forgetting to take the morning dose, but with numbers like these who gives a shit?

MtD

Offline Rev. Moon

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Re: Eat Me, Bitches
« Reply #1 on: August 24, 2010, 10:20:20 AM »
Superb VL drop ;)

"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

Offline Matty the Damned

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Re: Eat Me, Bitches
« Reply #2 on: August 24, 2010, 10:25:12 AM »
Superb VL drop ;)

Not just superb darling, fantabulosa.

MtD

Offline Zohar

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Re: Eat Me, Bitches
« Reply #3 on: August 24, 2010, 10:39:12 AM »
Well done with the numbers!

I'm interested in your combination, as I'm taking the same drugs but without the Raltegravir. Do you know what sort of level of benefit there is adding Raltegravir into the mix, and did you and the doctor discuss this combination without that particular drug?
''Poor is the man whose pleasures depend on the permission of another.''

Offline Matty the Damned

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Re: Eat Me, Bitches
« Reply #4 on: August 24, 2010, 10:43:43 AM »
Well done with the numbers!

I'm interested in your combination, as I'm taking the same drugs but without the Raltegravir. Do you know what sort of level of benefit there is adding Raltegravir into the mix, and did you and the doctor discuss this combination without that particular drug?

Oh honey I don't really know.

I was meant to be on this combo without the Truvada but Alain or possibly RAB suggested I needed to have it added. So I kvetched at my doctor to have it added.

And to shut me up, she agreed.

Frankly my eyes glaze over when Frau Eva discusses the drugs, so I'm not sure about the fucking details.

But to answer your question, yes I think raltegravir was always part of it.

MtD

Offline Zohar

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Re: Eat Me, Bitches
« Reply #5 on: August 24, 2010, 10:51:23 AM »
Interesting. Although I'm not sure I'd want to add a fourth pill to my regime and the one I'm on at the moment means I can take them all at once in the morning and then forget about it. Still, I might ask my doc about the benefits of Raltegravir with this particular combination when I have my next consultation.
''Poor is the man whose pleasures depend on the permission of another.''

Offline Matty the Damned

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Re: Eat Me, Bitches
« Reply #6 on: August 24, 2010, 10:56:15 AM »
Interesting. Although I'm not sure I'd want to add a fourth pill to my regime and the one I'm on at the moment means I can take them all at once in the morning and then forget about it. Still, I might ask my doc about the benefits of Raltegravir with this particular combination when I have my next consultation.

Honey, you can add whatever you want to your regimen. Just stop schmutzing my thread up with it. This is a Matty the Damned production and he performs alone.

So get off the fucking stage already.

MtD

Offline Miss Philicia

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Re: Eat Me, Bitches
« Reply #7 on: August 24, 2010, 10:57:00 AM »
3-drug HAART regimens are standard for initial treatment patients, or those that change regimens due to side effects.  A 4-drug regimen is often used for those with more advanced HIV, resistance issues and I guess *cough* adherence issues like the OP.
"Iíve slept with enough men to know that Iím not gay"

Offline Matty the Damned

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Re: Eat Me, Bitches
« Reply #8 on: August 24, 2010, 11:03:52 AM »
3-drug HAART regimens are standard for initial treatment patients, or those that change regimens due to side effects.  A 4-drug regimen is often used for those with more advanced HIV, resistance issues and I guess *cough* adherence issues like the OP.

Adherence is for losers and those who require a toupee.

MtD

Offline Jeffreyj

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Re: Eat Me, Bitches
« Reply #9 on: August 24, 2010, 11:04:00 AM »
Matty,
happy for you bud! I to am on the norvir/Prezista combo and I miss 20% of the dose the past month.. My t-4s are over 1,000 and unD viral load. My Dr. even prescribed one norvir per day (Instead of 2 per day) and reduced the Prezista. He is sure that my cholesteral will improve by this new dose! Your on to something good.

I'm happy for us both. Keep up the great work.
Jeff

Positive since 1985

Offline Miss Philicia

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Re: Eat Me, Bitches
« Reply #10 on: August 24, 2010, 11:18:22 AM »
Adherence is for losers and those who require a toupee.

MtD

I'll remember that when you take the Big Dirt Nap.
"Iíve slept with enough men to know that Iím not gay"

Offline Matty the Damned

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Re: Eat Me, Bitches
« Reply #11 on: August 24, 2010, 11:23:28 AM »
I'll remember that when you take the Big Dirt Nap.

Oh yeah. On that day I want you in your Class A Dress Wig.

With brocade bangs. :)

MtD

Offline allanq

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Re: Eat Me, Bitches
« Reply #12 on: August 24, 2010, 11:33:05 AM »
MtD,

You offer much sagacious advice on these forums. You can joke around about it all you want, but Iím surprised that with all your knowledge on matters HIV you still think adherence isnít important. Iím sure a brilliant mind like yours can come up with some way to remind yourself to take that morning dose. How about when you take the evening dose, put out the dose for the next morning in a place where youíll be sure to see it in the morning.

Itís great that youíre doing well. Please donít push your luck.

Allan
Top (Breakfast): Prezista, Norvir, Isentress, Zoloft (2), Glyburide (2), Aspirin
Bottom right (Dinner): Prezista, Norvir, Isentress
Bottom left (Bedtime): Sustiva, Trazodone (2), Lipitor, Septra (no longer taking this)
Center: Alprazolam (Xanax)
Not shown: various vitamins & supplements

Offline Ann

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    • Num is sum qui mentiar tibi?
Re: Eat Me, Bitches
« Reply #13 on: August 24, 2010, 11:45:46 AM »

Itís great that youíre doing well. Please donít push your luck.


If there's anything that Matty knows how to push, it's envelopes and luck. :)

And yes, it's great that he's doing so well.
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline Joe K

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Re: Eat Me, Bitches
« Reply #14 on: August 24, 2010, 11:49:02 AM »
Been on my new regimen (Raltegravir/Norvir/Truvada/Prezista) for a month or so.

Viral Load down from 96,000 to 496.

CD4 up from 12% to 14% (it's like in the 200s)

Oh yeah. :)

I keep forgetting to take the morning dose, but with numbers like these who gives a shit?

MtD

My Dear Damned,

This post just made my month. I am so happy for you and you better make sure that you are totally compliant with your meds. No excuses, you know better and if you won't do it for you, then please do it for me.

Joe

Offline GSOgymrat

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Re: Eat Me, Bitches
« Reply #15 on: August 24, 2010, 12:02:38 PM »
Eat me, Bitches

Well, consider yourself eaten...

and congrats on the numbers! :)

Offline Miss Philicia

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Re: Eat Me, Bitches
« Reply #16 on: August 24, 2010, 12:04:53 PM »
Eat me, Bitches

Well, consider yourself eaten...

At her weight we'd all be sitting at the table eating for days.
"Iíve slept with enough men to know that Iím not gay"

Offline skeebo1969

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Re: Eat Me, Bitches
« Reply #17 on: August 24, 2010, 12:06:58 PM »
Congrats on the Vl drop.  I'm going to play 496 straight on cash 3 tonight!

I keep forgetting to take the morning dose, but with numbers like these who gives a shit?

MtD

It's the main dose I miss as well.  I've resorted to taking it at different hours to keep from missing it all together, but for some reason still manage to miss at least one dose a week on average.  Shits hard man...fuck.




I despise the song Love is in the Air, you should too.

Offline Matty the Damned

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Re: Eat Me, Bitches
« Reply #18 on: August 24, 2010, 12:08:32 PM »
Oh man, taking these pills is like dealing with an Ikea flat pack. There's always a handful of piddling little things left over.

I mean seriously, after a girl has washed down her bran flakes with a litre of Irish Cream what's she meant to do? One side of the dosette box looks much like the other. :)

So I take the fucking pills. But since I don't have the sainted Dr Gallant to guide me along the way I make the occasional mistake. ;)

MtD

Offline Joe K

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Re: Eat Me, Bitches
« Reply #19 on: August 24, 2010, 01:59:09 PM »
It's the main dose I miss as well.  I've resorted to taking it at different hours to keep from missing it all together, but for some reason still manage to miss at least one dose a week on average.  Shits hard man...fuck.

Come on guys, get with the program. Get yourself a pill box, that breaks down by day and/or time and then you can fill it and forget it. I have one that splits each day into four sections, but I only take pills twice daily, so that gives me two full weeks of pills in one case. If I think I missed a pill, a quick check will tell me. I have had drug regimens that baffled the human mind and without pill cases, I would not still be here.

I can't buy this missed dose talk, as if it were unimportant. Get a grip, get organized and get compliant.

Offline Assurbanipal

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Re: Eat Me, Bitches
« Reply #20 on: August 24, 2010, 02:02:11 PM »
Oh man, taking these pills is like dealing with an Ikea flat pack. There's always a handful of piddling little things left over.

I mean seriously, after a girl has washed down her bran flakes with a litre of Irish Cream what's she meant to do? One side of the dosette box looks much like the other. :)

So I take the fucking pills. But since I don't have the sainted Dr Gallant to guide me along the way I make the occasional mistake. ;)

MtD


Here you go Matty -- cut out the picture and paste it on your ceiling...right over the cereal bowl.  
http://research.hopkinsglobalhealth.org/GlobalFacultyPage.cfm?global_faculty_id=30

or on the pill box...



Mr. Urban


5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%

Offline AlanBama

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  • Alabama: the 'other' 3rd World Country!
Re: Eat Me, Bitches
« Reply #21 on: August 24, 2010, 02:22:08 PM »
Great news honey!  I'm "right proud" of you, as we say here in hicksville... ;)

I'm with Joe:  I wouldn't be alive if it were not for the weekly pill boxes.

Congrats !!!
"Remember my sentimental friend that a heart is not judged by how much you love, but by how much you are loved by others." - The Wizard of Oz

Offline Jeff G

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  • How am I doing Beren ?
Re: Eat Me, Bitches
« Reply #22 on: August 24, 2010, 03:26:07 PM »
Great news , well done  ... take your fucking pills .

Offline Snowangel

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Re: Eat Me, Bitches
« Reply #23 on: August 24, 2010, 03:31:01 PM »
Nice job, Matty!

Programming your cell phone alarm helps, it's an annoying reminder, but it works.
Of all the things you wear, your expression is the most important

The heaviest thing you can carry is a grudge..

One thing you can give and still keep...is your word.

One thing you can't recycle is wasted time.

Offline newt

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Re: Eat Me, Bitches
« Reply #24 on: August 24, 2010, 04:12:07 PM »
Ah Matty, britches eater

You know adherence is important...

On this combo I reckon once a day, all in on go will do, ask the Ice Queen or A N Other.

God result :-)

- matt

Now playing: Hurts, Wonderful Life
"The object is to be a well patient, not a good patient"

Offline gemini20

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Re: Eat Me, Bitches
« Reply #25 on: August 24, 2010, 04:17:01 PM »
Pretty impressive numbers for a month in - well done!

As for adherence - I can't berate you for that as I still miss doses and not through forgetting either, but just because I choose not to take the odd day or two every now and again!

Do what works for you until the numbers start telling you otherwise.


Emma
Diagnosed 11th September 1991
Current CD4 count 484 (26%); viral load undetectable (December 2011).
Restarting boosted Prezista 08/04/11

Offline Boze

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Re: Eat Me, Bitches
« Reply #26 on: August 24, 2010, 04:21:26 PM »
Good to hear, keep at it!
==========
Aug08 - Seroconversion
Mar10 - Diagnosis; cd4 690 - VL 19,000
Apr10 - cd4 600
May10 - VL 4,500
Jun10 - started Atripla ; VL 113
Jul 10 - UD vl, CD4 590
Aug 10 - UD, CD4 810, 52%
Nov 10 - UD, CD4 980

Offline numbersguy82

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Re: Eat Me, Bitches
« Reply #27 on: August 24, 2010, 07:09:30 PM »
This is really awesome news... Congrats on the improvement. Here's to much more improvement in the coming months!
8/10- 73 cd4, 7%, and 300k VL *First Labs*
9/10- Started Norvir, Prezista, and Truvada
10/10- 511 cd4, 22%, and 886 VL
12/10- 498 cd4, 22%, and 106 VL
3/11- 529 cd4, 29%, and 101 VL
8/11- 620 cd4, 30%, and 74 VL- Switched to Atripla
10/11- 580 ce4, 30%, and 62 VL
12/11- 684 cd4, 31%, and FINALLY *UD*

Offline WillyWump

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Re: Eat Me, Bitches
« Reply #28 on: August 24, 2010, 09:38:33 PM »
Congrats Matty!!

-Willster
POZ since '08

Last Labs-
6/3/14 CD4- 736, UD 34%
6/25/13 CD4- 1036, UD,
2/4/13, CD4 - 489, UD, 28%

Current Meds: Prezista/Epzicom/ Norvir
.

Offline tednlou2

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Re: Eat Me, Bitches
« Reply #29 on: August 25, 2010, 12:18:16 AM »
Come on guys, get with the program. Get yourself a pill box, that breaks down by day and/or time and then you can fill it and forget it. I have one that splits each day into four sections, but I only take pills twice daily, so that gives me two full weeks of pills in one case. If I think I missed a pill, a quick check will tell me. I have had drug regimens that baffled the human mind and without pill cases, I would not still be here.

I can't buy this missed dose talk, as if it were unimportant. Get a grip, get organized and get compliant.

Or, there is this:

http://www.vitality.net/glowcaps.html

Matty, I'm glad to hear things are going well!

Offline northernguy

  • Member
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Re: Eat Me, Bitches
« Reply #30 on: August 25, 2010, 12:43:04 AM »
Great news!  :)
Apr 28/06 cd4 600 vl 10,600 cd% 25
Nov 8/09 cd4 510 vl 49,5000 cd% 16
Jan 16/10 cd4 660 vl 54,309 cd% 16
Feb 17/10 Started Atripla
Mar 7/10 cd4 710 vl 1,076 cd% 21
Apr 18/10 cd4 920 vl 268 cd% 28
Jun 19/10 cd4 450 vl 60 cd% 25
Aug 15/10 cd4 680 vl 205 cd% 27
Apr 3/11 cd4 780 vl <40 cd% 30
Jul 17/11 cd4 960 vl <40 cd%33
April 15/12 cd4 1,010 vl <40 cd% 39
April 20/12 Switched to Viramune + Truvada
Aug 2/12 cd4 1040, vl <40, cd% 38
Oct 19 cd4 1,110 vl <40 cd% 41

Offline aztecan

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  • 29 years positive, 57 years a pain in the butt
Re: Eat Me, Bitches
« Reply #31 on: August 25, 2010, 01:48:59 AM »
Hey Matty,

Impressive results. Now, keep it up (taking the damn pills, I mean!  ;))

HUGS,

Mark
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline BT65

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Re: Eat Me, Bitches
« Reply #32 on: August 25, 2010, 04:09:24 AM »
Great results, Sweet D.O.   I hope they just get better and better (like you, my dear). 

By the way, I used to love Bailey's and coffee, so I'm with you on the Irish cream.
I've never killed anyone, but I frequently get satisfaction reading the obituary notices.-Clarence Darrow

Offline Hellraiser

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Re: Eat Me, Bitches
« Reply #33 on: August 25, 2010, 07:26:27 AM »
Congrats Mattylicious on your excellent results.  I never suspected you as the Devil-may-care type for pill taking though.

Offline Matty the Damned

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Re: Eat Me, Bitches
« Reply #34 on: August 25, 2010, 05:11:56 PM »
Ah Matty, britches eater

You know adherence is important...

On this combo I reckon once a day, all in on go will do, ask the Ice Queen or A N Other.

God result :-)

- matt

Now playing: Hurts, Wonderful Life


Once a day? Now that's what I wanna hear. I'll ask Der Frau.

MtD

Offline newt

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Re: Eat Me, Bitches
« Reply #35 on: August 25, 2010, 05:37:50 PM »
She will say NO but:

The pharmokinetics of all drugs is good enough. Specifically, raltegravir has a long half-life, and is being tested as once-a-day right now, with good first results. Darunavir is approved once a day for treatment-naive people, so the PK works, and truthfully if you are on the 600mg dose the difference between 1 and 2 times a day in terms of effectiveness is unlikely to mean anything in practice, plus it is considerably better than missing a dose from a 2 x daily schedule.

- matt
"The object is to be a well patient, not a good patient"

Offline Miss Philicia

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Re: Eat Me, Bitches
« Reply #36 on: August 25, 2010, 05:40:07 PM »
Once-a-day dosing is for plebes.
"Iíve slept with enough men to know that Iím not gay"

Offline newt

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Re: Eat Me, Bitches
« Reply #37 on: August 25, 2010, 05:43:37 PM »
Count me a pleb then, I am proud to be a common or garden 1 x day doser
"The object is to be a well patient, not a good patient"

Offline Dachshund

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Re: Eat Me, Bitches
« Reply #38 on: August 25, 2010, 07:10:05 PM »
I'm on the same regimen and it's once a day for Aunty D.

Offline Rev. Moon

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Re: Eat Me, Bitches
« Reply #39 on: August 25, 2010, 07:13:50 PM »
Once-a-day dosing is for plebes.

There are many plebeians in this here joint then.  Just ask any of the Atripla chirrens.  And here I always thought that I was royalty.
"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

Offline Hellraiser

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Re: Eat Me, Bitches
« Reply #40 on: August 25, 2010, 07:16:40 PM »
There are many plebeians in this here joint then.  Just ask any of the Atripla chirrens.  And here I always thought that I was royalty.


You'll always be a Queen to me, dearest.

Offline Rev. Moon

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Re: Eat Me, Bitches
« Reply #41 on: August 25, 2010, 07:20:43 PM »

You'll always be a Queen to me, dearest.

Oh, you're so sweet, my dear Duchess.
"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

Offline Hellraiser

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Re: Eat Me, Bitches
« Reply #42 on: August 25, 2010, 07:22:03 PM »
Oh, you're so sweet, my dear Duchess.

Does that make me like Fergie, minus the pissing myself on stage?

Offline hope_for_a_cure

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Re: Eat Me, Bitches
« Reply #43 on: August 25, 2010, 08:40:07 PM »
Great news Matty! 

Offline emeraldize

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Re: Eat Me, Bitches
« Reply #44 on: August 25, 2010, 09:14:54 PM »
MtD

Amazing. You must be relieved. As Newt noted the current study of once-a-day Raltegravir caused me to ask a couple ofdocs about it (as that's what I'll restart in another month). They affirm and one said while they wouldn't "agree to it" they concede patients having been using it off-label at once a day with great results.

With your clever graphics abilities, couldn't you doll up your pillbox to make it an attractive place to visit twice a day?

Em

Granny60

  • Guest
Re: Eat Me, Bitches
« Reply #45 on: August 25, 2010, 11:50:04 PM »
Hey Matty the beach eater, That's some super kicking butt, but tell me dear boy,  isn't eating  bitches what got you in this mezz to begin with?? ;D :D KIck their sorry ass!

Offline john33

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Re: Eat Me, Bitches
« Reply #46 on: August 26, 2010, 06:32:43 AM »
Mtty, thats great news that your numbers are going in the right direction.

John

Offline Matty the Damned

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  • Posts: 12,228
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Re: Eat Me, Bitches
« Reply #47 on: August 26, 2010, 04:50:28 PM »
She will say NO but:

The pharmokinetics of all drugs is good enough. Specifically, raltegravir has a long half-life, and is being tested as once-a-day right now, with good first results. Darunavir is approved once a day for treatment-naive people, so the PK works, and truthfully if you are on the 600mg dose the difference between 1 and 2 times a day in terms of effectiveness is unlikely to mean anything in practice, plus it is considerably better than missing a dose from a 2 x daily schedule.

- matt


Took the whole bloody dose last night. Still alive this morning. :)

I might not tell the Frau. Don't want her to go having a conniption.

MtD

 


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