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Author Topic: 06/10 Starting Viramune (Nevirapine) + Kivexa (Epzicom = 3TC / abacavir)  (Read 51924 times)

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Offline eric48

  • Member
  • Posts: 1,172
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
With 4 parameters I can fit an elephant. With 5 I can make it wiggle his trunk

recommended reading
Dynamics of Cancer : Incidence, Inheritance, and Evolution by Steven A Frank
http://tinyurl.com/cm8blnc

Dynamics are generally speaking less known to the public. No need to read in detail, just browse thru
This book emphasize the use of speeds (time derivatives) and acceleration, just as we did in previous posts, as a framework for better model validation.

Having a model would be more fun if it were predictive: let's give it a try

Forecast for upcoming blood draw (aka ImmunoForecast)

CD4 % around 49
CD4 > 1100 but less than 1300; estimated at 1100
CD8 % around 23
CD8 estimated at 520
CD4/CD8 around 2.1

Still open:
Quiz : In CD4, what means C , D and 4 ?

« Last Edit: May 06, 2014, 09:24:26 PM by Jeff G »
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 2 months

Offline Hellraiser

  • Member
  • Posts: 4,136
  • Semi-misanthropic
Quiz : In CD4, what means C , D and 4 ?

Cluster of Differentiation 4

Offline eric48

  • Member
  • Posts: 1,172
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
We have not finished. Meds have cured noone (*). And that is the problem

(*) with exception of Viscontis and a handfull of others

Thanks ! Yep ... See:
http://en.wikipedia.org/wiki/CD4

No room on a post like this to explain C and D, but maybe one can easily explain the 4 (in relation to 8)...

Since my previous post included a prediction and blood test was done May 12, I now know the quality of the prediction exceeds my expectations. In order to set expectations right I have published a foreword to put in perspective how a predictive model should be tested and prove its worth.

Here again there is no room here to publish this (too many numbers), so I have published on the Tumblr account. I am new to Tumblr so there is a learning curve. Also I'll wrap this up into graphs , easier to read, but this takes time ...

www.tinyurl.com/HIVPharmaCure-T1

I'll post the graphs here as well.

Visit to Doc:  UD as usual...
He offers Complera, but, no, I want to stay on Viramune. I am starting using generics (Mylan) and I want to report to fellow Viramune users

May 12 started  Boneozard

Quiz : In CD4, what means 4 ?

Stay tuned : @HIVPharmaCure (pls RT)       Cheers ! Eric
pointer : http://tinyurl.com/HIVPharmaCure-24 (please do not copy, do not highjack, thanks!)
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 2 months

Offline eric48

  • Member
  • Posts: 1,172
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
just to add : I have kept this thread active for four years : this is the 4 y. anniversary
Also I'd like to change the quiz question from
Quiz : In CD4, what means 4 ?
to Quiz : In CD8, what means 8 ?  Eric
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 2 months

Offline eric48

  • Member
  • Posts: 1,172
  • @HIVPharmaCure & tinyurl.com/HIVPharmaCure
Mathematics is ultimately no more, but no less, than thinking very clearly about things. And I like puzzles

recommended readings
NCBI Bookshelf provides free access to books and documents in life science and healthcare.
http://www.ncbi.nlm.nih.gov/books
Amazingly rich... Incredibly cheap

VHC sexually transmitted ? Yes ? No ? Yes? Tbd
http://www.aidsmeds.com/articles/sexual_transmission_HCV_2042_25673.shtml
http://www.thebody.com/content/74859/studies-investigate-presence-of-hepatitis-c-virus-.html

I have published on the Tumblr account details of prediction analysis.
I have also made the graphs, easier to read...

www.tinyurl.com/HIVPharmaCure-T1

Thread split  I am splitting posts:
- Reservoirs : on tumblr
- Nevirapine (aka Viramune (tm)) : here as always
- Tivicay (coming soon...) : undecided yet 

Recent Labs: 
2014-05-12: CD4 : 1130 CD4%: 46 CD8: 491 CD8%: 20 CD4/CD8: 2.3
2014-07-15: CD4: 1016 CD4%: 43 CD8: 662 CD8%: 28 CD4/CD8: 1.5

Next Labs   around Sept 15. CD4 on Up trend; CD8% on down trend

Generics
I am starting using generics (Nevirapine Mylan)
Except for the emboss they look just so identical... even under the microscope
My branded Viramune (tm) 200 mg is made in Germany 
My generic Nevirapine 200 mg is made in... Germany
My generics are not that cheap : no wonder

Quiz : It was known it is a Virus somewhat before the virus was identified. How ?

Stay tuned : @HIVPharmaCure (pls RT)       Cheers ! Eric
pointer : http://tinyurl.com/HIVPharmaCure-25 (please do not copy, do not highjack, thanks!)
NVP/ABC/3TC/... UD; CD4 > 1000; CD4/CD8 ~ 2.0   safety stock : 2 months

 


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