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Author Topic: Buffalo hump  (Read 2770 times)

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Offline tokyodecadence

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  • Posts: 234
  • A one room disco.
Buffalo hump
« on: April 28, 2010, 07:09:37 AM »
I was just reading another thread where someone talks about buffalo hump. I'm really foggy on the whole side effect, can anyone explain?

What causes it? Is it just the HIV meds, or is it like a combination of meds, lifestyle, etc.? Which meds usually cause this type of reaction? Is it something that occurs after years of taking meds?

Is there anything that can be done preemptively to avoid it? From what I've read, it seems to be under the realm of lipodystrophy in general. Is it a type of lipodystrophy, or someone that comes along with having lipodystrophy?



Thanks in advance for any information! I'm really just curious as to how the whole thing works is all, in the even that I one day have to deal with it.
[.Fodão.]

Offline Moffie65

  • Member
  • Posts: 1,755
  • Living POZ since 1983
Re: Buffalo hump
« Reply #1 on: April 28, 2010, 09:49:32 AM »
First off, I have both heard and experienced that the relocation of fat from the extremities, Lipodistrophy,  is caused by both the medications and HIV itself.  I am not too sure about the HIV cause, but I know that it is directly connected to some of the drugs.  I have had both a hump, and a third breast form, and it was caused by Norvir and Kaletra.  Both of these drugs are suspended in "Olestra", which is a synthetic oil that doesn't cause us to get fat, yet the body treats it as waste, and sometimes deposits it somewhere in the body.  I have been told my theory about Olestra being the cause of Buffalo Hump, is nothing but sheer conjecture, but until studies are done, I will stick to my supposition.  Yes, I have been on both, but not necessarily at the same time.  The hump pretty much doesn't bother me, except that it places some pressure on the upper part of my spine, but mostly it is something other people can see and not me, so I don't worry about it.  The third breast, located right between the other two, is also not terribly annoying because it is just there.  The thing I do miss is the fat on my legs that kept my Levis 501s looking so good on me, but so be it, I am no longer a young man, so it really doesn't matter. 

Mostly, it is the re-distribution of fat that happens to us if we are priveleged to live a long life anyway, so either you obsess about something that is natural, but happens much earlier, or you simply accept that this is one thing that you might have to deal with and move on.  Just like so many things in HIV, this is just a very simple, but sometimes annoying thing that most of us deal with at some point or another.  Don't fret, it isn't life changing, so I hope this helps.
The Bible contains 6 admonishments to homosexuals,
and 362 to heterosexuals.
This doesn't mean that God doesn't love heterosexuals,
It's just that they need more supervision.
Lynn Lavne

Offline Miss Philicia

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  • Posts: 23,880
  • celebrity poster, faker & poser
Re: Buffalo hump
« Reply #2 on: April 28, 2010, 10:18:52 AM »
I was just reading another thread where someone talks about buffalo hump. I'm really foggy on the whole side effect, can anyone explain?

What causes it? Is it just the HIV meds, or is it like a combination of meds, lifestyle, etc.? Which meds usually cause this type of reaction? Is it something that occurs after years of taking meds?

Is there anything that can be done preemptively to avoid it? From what I've read, it seems to be under the realm of lipodystrophy in general. Is it a type of lipodystrophy, or someone that comes along with having lipodystrophy?



Thanks in advance for any information! I'm really just curious as to how the whole thing works is all, in the even that I one day have to deal with it.

read this: http://emedicine.medscape.com/article/1082199-overview
"I’ve slept with enough men to know that I’m not gay"

Offline GDMatDSM

  • Member
  • Posts: 3
Re: Buffalo hump
« Reply #3 on: April 28, 2010, 11:00:27 AM »
I had the hump.  For several years while on one of the many medications I have taken over the past 25 years I developed the infamous hump.  It provided little to no discomfort besides making some shirts look awkward.  After changing medications the hump started to disappear and there is only a small remnant left that barely anyone would notice.  It did add a little pressure to the upper spine although not painful.  I was glad the medication did its job in regards to the HIV until the next medication was needed.  I am a long term survivor who has never had an opportunistic disease.  May you have the same road to travel. Have no fear.

Offline Hellraiser

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  • Posts: 4,136
  • Semi-misanthropic
Re: Buffalo hump
« Reply #4 on: April 28, 2010, 11:19:19 AM »
I haven't heard of anyone developing a buffalo hump in recent years which makes me tend to think that this was medication related and specific to the older medications?  Can anyone verify any of that?

Offline Miss Philicia

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  • celebrity poster, faker & poser
Re: Buffalo hump
« Reply #5 on: April 28, 2010, 11:36:59 AM »
I haven't heard of anyone developing a buffalo hump in recent years which makes me tend to think that this was medication related and specific to the older medications?  Can anyone verify any of that?

That's my take on the issue as well.  Everyone I personally know with lipohypertrophy got as a result of medication used in the 90's, and which are not on the list of "preferred" HIV treatment currently.

My recommendation is for people new on treatment not to particularly fixate on this.
"I’ve slept with enough men to know that I’m not gay"

Offline aztecan

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  • Posts: 5,382
  • 29 years positive, 56 years a pain in the butt
Re: Buffalo hump
« Reply #6 on: April 29, 2010, 01:17:27 AM »
That's my take on the issue as well.  Everyone I personally know with lipohypertrophy got as a result of medication used in the 90's, and which are not on the list of "preferred" HIV treatment currently.

My recommendation is for people new on treatment not to particularly fixate on this.

Yep, that is the most accepted theory. It may be associated with some of the older nukes, specifically Zerit, AZT and Videx.
It also may be caused by some of the early PIs, specifically Crixivan and Norvir, back when Norvir was a treatment not a boosting agent.

I have my hump that probably came as a result of taking AZT, Epivir and Crixivan for a dozen years or so.

The newer meds don't seem to do this, as our Philly said, so I wouldn't be too concerned with it at this time.

Actually, I bitch and moan, but I am very grateful for the meds we had when we had them. So, a dozen years later I have a hump, chipmunk cheeks, a goiter-like neck and skinny legs and arms, and a bit of sunken cheeks and no ass.

But I am still her to kvetch about it. So, I am grateful.

HUGS,

Mark

"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline tokyodecadence

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  • Posts: 234
  • A one room disco.
Re: Buffalo hump
« Reply #7 on: April 29, 2010, 01:24:52 AM »
Thank you all for the responses. But I should note that I'm not really worried about it, I was just curious about how they come about. I'd only really heard of them in passing on one thread or another, and it sparked my interest.



And Miss P, your link is temporarily unavailable. I'll have to click again at some point....if I can remember.
[.Fodão.]

Offline mecch

  • Member
  • Posts: 11,218
  • red pill? or blue pill?
Re: Buffalo hump
« Reply #8 on: April 29, 2010, 09:49:51 AM »
These body concerns should be discussed with the specialist and newly infected newly treated people should really pay attention to the professional response. 

We see all the time in here HIV- people who become obsessed that they MUST be HIV+, and similarly, we see newly infected/ or treated people who are convinced they have lipo atrophy or dsytrophy within months of treatment.  This seems to be a kind of anxiety mixed with body dysmorphic disorder.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline tokyodecadence

  • Member
  • Posts: 234
  • A one room disco.
Re: Buffalo hump
« Reply #9 on: April 29, 2010, 05:39:36 PM »
These body concerns should be discussed with the specialist and newly infected newly treated people should really pay attention to the professional response. 

We see all the time in here HIV- people who become obsessed that they MUST be HIV+, and similarly, we see newly infected/ or treated people who are convinced they have lipo atrophy or dsytrophy within months of treatment.  This seems to be a kind of anxiety mixed with body dysmorphic disorder.

I'm going to assume that you're not referring to the OP (namely, me), because I'm not newly poz, nor am I some obsessed hiv- person, nor do I think I have any sort of symptom. If that was directed towards me, then you need to re-read this post.
[.Fodão.]

Offline mecch

  • Member
  • Posts: 11,218
  • red pill? or blue pill?
Re: Buffalo hump
« Reply #10 on: April 29, 2010, 06:44:56 PM »
Nope, it was directed at whoever might read the thread. Nothing personal intended, and sorry if i expressed my opinion clumsily
“From each, according to his ability; to each, according to his need” 1875 K Marx

 


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