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Author Topic: Hiv meds one week on/one week off  (Read 1780 times)

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Offline kuttakamina

  • Member
  • Posts: 45
Hiv meds one week on/one week off
« on: April 01, 2010, 03:40:09 AM »
A few months ago there was a poster who said he's doing one week on/one week off with Atripla for over a year, had no issues, no resistance.

Do we know if he's around? Do we know if anybody else has tried that? Is it too dangerous to try? After all, it may indeed give a break to a stressed liver? The doc thinks it's a bad idea but wouldn't give any explanation.

Offline Hellraiser

  • Member
  • Posts: 4,136
  • Semi-misanthropic
Re: Hiv meds one week on/one week off
« Reply #1 on: April 01, 2010, 04:08:57 AM »
That's being really cavalier with the medication.  Someone else is doing 5 days on 2 days off which seems more realistic.

Offline phildinftlaudy

  • Member
  • Posts: 2,959
  • sweet Ann what you think babe...
Re: Hiv meds one week on/one week off
« Reply #2 on: April 01, 2010, 07:48:54 AM »
I wouldn't do it unless I was seriously low on meds and didn't know or was working on where my next script was coming from or if my doc told me I had to do it.....   I don't want to have any resistance issues.
September 13, 2008 - diagnosed +
Labs:
Date    CD4    %   VL     Date  CD4  %   VL
10/08  636    35  510   9/09 473  38 2900  12/4/09 Atripla
12/09  540    30    60   
12/10  740    41  <48   
8/11    667    36  <20  
03/12  1,041  42  <20
05/12  1,241  47  <20
08/12   780    37  <20
11/12   549    35  <20
02/12  1,102  42  <20
11/12   549    35  <20

Offline leatherman

  • Member
  • Posts: 6,061
  • Google and HIV meds are Your Friends
Re: Hiv meds one week on/one week off
« Reply #3 on: April 01, 2010, 09:47:40 AM »
The doc thinks it's a bad idea but wouldn't give any explanation.
According to the research, being less than 93-95% compliant allows the level of meds in your system to drop low enough to not be effective enough to destroy the HIV cells, letting them replicate and mutate to become resistant to the meds. When the meds are no longer effective, then HIV wins. :(

Of course the doc thinks it's a bad idea. ;) Having an incurable, terminal illness (or any illness/condition) and only taking the meds half-assed is incredibly stupid and doesn't really deserve an explanation. If someone doesn't care about their health enough to follow their doctor's advice/instructions, many doctors get a little uncaring about the situation too.

Plus Atripla (and all the other meds) don't necessarily stress anyone's liver. (for myself, through 15 meds over 20 yrs, I've never had liver, BP, or cholesterol issues) Anyone that is having such adverse reactions can usually switch to other treatments or take another medication to help with the problem. ;)
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline aztecan

  • Member
  • Posts: 5,384
  • 29 years positive, 56 years a pain in the butt
Re: Hiv meds one week on/one week off
« Reply #4 on: April 01, 2010, 10:29:40 AM »
A few months ago there was a poster who said he's doing one week on/one week off with Atripla for over a year, had no issues, no resistance.

Do we know if he's around? Do we know if anybody else has tried that? Is it too dangerous to try? After all, it may indeed give a break to a stressed liver? The doc thinks it's a bad idea but wouldn't give any explanation.

The explanation is this: To follow this line of adherence would be opening the door to resistance issues and drug failure.

Period.

I also know the person here who is taiking it five days on, two days off. I also happen to know he has been having "issues," although I am not sure of the extent.

The bottom line is you are worried about your liver, but it won't do you any good to ignore the virus to protect your liver. As Leatherman noted, less than 95 percent adherence is begging for trouble.

HUGS,

Mark
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline metekrop

  • Member
  • Posts: 354
Re: Hiv meds one week on/one week off
« Reply #5 on: April 01, 2010, 11:07:21 AM »
A few months ago there was a poster who said he's doing one week on/one week off with Atripla for over a year, had no issues, no resistance.

Do we know if he's around? Do we know if anybody else has tried that? Is it too dangerous to try? After all, it may indeed give a break to a stressed liver? The doc thinks it's a bad idea but wouldn't give any explanation.

I don't think this is advisable.  Getting off the med would automatically result in drug resistant and illness.  Once you started the med you should adhere to it.  Else there are a dozen of OI who are waiting to take the advantage there from.
Diag on Dec 8, 2000, CD 440 VL 44K, No Meds
Dec/08 - Feb/09 CD< 50 & VL >500k hosp'z.
St. Atripla - July/09 CD 179, VL 197k
Oct/09 CD 300 VL UD Chol 267
Mar/10 CD 468 UD, Ch 220
Aug/10 CD 460 UD, Ch 195
Dec/10 CD 492 UD, Ch 172
Mar/11 CD 636 UD, Ch 201
Aug/11 CD 530 UD, Ch 98
Jan/12 cd 616 UD, ch 189
Jul/12 CD 640 UD, Ch ?
Dec/12 CD 669 Ud, Ch 125
May/7 CD711 Ud, Ch?
Nov/ 22 663 UD, Ch,
April 17 CD 797, UD

Offline Inchlingblue

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  • Posts: 3,119
  • Chad Ochocinco PETA Ad
Re: Hiv meds one week on/one week off
« Reply #6 on: April 01, 2010, 02:09:36 PM »

 


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