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Author Topic: Are there different strains of HIV??  (Read 1575 times)

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Offline dingowarrior

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  • Posts: 191
Are there different strains of HIV??
« on: February 22, 2010, 11:41:18 PM »
Hi all, I've read here and other places where HIV + folks take several pills a day..Where I and many other take 1 pill a day.
Are there different strains of HIV?

Offline Matty the Damned

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Re: Are there different strains of HIV??
« Reply #1 on: February 22, 2010, 11:54:46 PM »
There are different strains and subtypes of HIV, but as far as I know, these have no bearing on what sort of treatments people take.

The regimen recommend to an individual reflects their particular circumstances - things like resistance, tolerance for side effects, other medical conditions and so forth.

MtD

Offline Hellraiser

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Re: Are there different strains of HIV??
« Reply #2 on: February 23, 2010, 12:06:32 AM »
I believe the strains are largely geographically based.  North America, Africa, and Asia being the major regions.  Actually I'm wrong... 2 types and a ton of subtypes....


http://www.avert.org/hiv-types.htm

Offline Grasshopper

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Re: Are there different strains of HIV??
« Reply #3 on: February 23, 2010, 01:53:53 AM »
several pills a day..&... 1 pill a day.


several pills = each pill being a seperate medicine
&
1 pill = a combination of the above in a single pill

Therapy with a single pill being a single medicine, the so called monotherapy is outdated, and not done anymore.

Offline RapidRod

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  • Posts: 15,276
Re: Are there different strains of HIV??
« Reply #4 on: February 23, 2010, 03:50:34 AM »
There are two types. HIV1 and HIV2
There are 4 groups. M,N,O and P
Under HIV1, group M you have the following subtypes. These are subtypes A, B, C, D, F, G, H, J, K and CFRs.

Offline veritas

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Re: Are there different strains of HIV??
« Reply #5 on: February 23, 2010, 04:58:09 AM »

Warrior,

There are HIV types, subtypes,  strains  and groups. The different type of medications hit the virus at various positions in it's development (ie: Protease, reverse transcriptase, integrace etc.). The virus uses these mechanisms in all strains and subtypes etc. so the medications are effective for all types. A problem might come in the development of a vaccine where it might be difficult to find a common area on all strains and subtypes that the vaccine can go after ( both therapeutically and preventativly speaking) This link will give you a pretty good overview:


http://www.avert.org/hiv-types.htm


v

Offline Hellraiser

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Re: Are there different strains of HIV??
« Reply #6 on: February 23, 2010, 08:38:03 AM »
Veritas you just linked the same thing I did 4 posts earlier lol.

Offline Moffie65

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  • Living POZ since 1983
Re: Are there different strains of HIV??
« Reply #7 on: February 23, 2010, 10:27:39 AM »
Hi all, I've read here and other places where HIV + folks take several pills a day..Where I and many other take 1 pill a day.

Dingo, as has already been very well explained, the strains of HIV have nothing to do with the HAART coctail.  For example, my virus is now resistant to every drug out there EXCEPT Raltegravir, Darunavir, Lamivudine, and to the best of my knowledge, Fuseon.  I am highly allergic to AZT, and many of the combination drugs (one pill form) have it in them.  So, my therapy isn't a particular choice for me or many LTSers, it is just the only thing we can take to keep the virus under control.  So, stay on your drugs so that your virus doesn't become resistant, and pray that your coctail never fails.  At this point, none of us actually know how long therapy will last in our bodies, it is pretty much up to the virus.
The Bible contains 6 admonishments to homosexuals,
and 362 to heterosexuals.
This doesn't mean that God doesn't love heterosexuals,
It's just that they need more supervision.
Lynn Lavne

Offline Inchlingblue

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Re: Are there different strains of HIV??
« Reply #8 on: February 23, 2010, 10:32:51 AM »
The one pill you take, which I assume is Atripla, is actually three different medications that have been combined and are sold as one pill, for convenience. So you are on three HIV medications, which for the time being is the standard of care.

There are some individuals whose HIV has become resistant to one or more of the existing drugs and/or classes of drugs and these people usually need to take more than three medications.

There are also some individuals, not many, who are doing well on Kaletra monotherapy. Kaletra is one pill that includes a protease inhibitor plus a booster. Boosted Prezista monotherapy has also been shown to work in some people.

More and more studies are looking at the possibility of streamlining treatment to see if HIV can be controlled with fewer than the standard three medications. For example Isentress and Reyataz has performed well in early studies. If it's shown to work, this would control HIV with only two medications.

Basically, the number of pills is not usually indicative of the number of medications since several of the pills include more than one medication in them (Truvada is one pill with two medications in it, for example).

There are two HIV types (HIV-1 and HIV-2). The great majority of people have HIV-1 and most medications have been designed to work against HIV-1. There are fewer meds available that work against HIV-2 but, on the bright side, it progresses to AIDS much more slowly than HIV-1 does.

Offline veritas

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Re: Are there different strains of HIV??
« Reply #9 on: February 23, 2010, 01:24:47 PM »

Hellraiser,

Great minds think alike! LOL
(should have opened all the links--my bad)
v

 


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