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Author Topic: Both Partners Positive...Will Have Same Genotype?  (Read 1351 times)

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Offline 1228GUY

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  • Posts: 64
Both Partners Positive...Will Have Same Genotype?
« on: January 16, 2010, 12:31:00 PM »
Question... If both partners are positive, and they both became positive from one another, don't know who was positive first (it really doesn't matter, I'm working on learning how not to give disclosure of "I dont know who had it first" since it really is irrelevant based on the fact that we are both positive) I'm sure some here can relate to these questions that when we were negative we would often ask of a positive person but now that we are on the other side of the fence, we truly understand how irrelevant these questions can be because it changes nothing, it does not take the virus away..... I've shifted from my question, venting! Here we go again....

Both partners positive, became positive from one another, will the virus Genotype? Strain? (new to all this terminology) be the same? Exactly the same?  Same Drug Resistance? I would assume it would be but I do not know and don't trust too much of what I Google.....

Thanks!!!

Guy
« Last Edit: January 16, 2010, 12:41:44 PM by 1228GUY »
12.28.09 - Rcvd call I should test
12.29.09 - Confirmed
01.19.10 - VL 30015  CD4 172
03.18.10 - VL 1627    CD4 193
04.15.10 - VL 965      CD4 248
07.09.10 - VL 227      CD4 233 (19%)
08.12.10 - VL 99        CD4 280 (18%)
12.03.19 - VL 79        CD4 262 (21%)
02.09.11 - VL 90        CD4 376 (19%)
05.20.11 - VL 106      CD4 196 (25%)
06.23.11 - VL 82        CD4 289
08.05.11 - VL UD       CD4 286
11.04.11 - VL 54        CD4 305
03.02.12 - VL UD       CD4 523
04.30.12 - VL 74
08.12.12 - VL 153      CD4 353
11.15.12 - VL 43        CD4 443
01.11.13 - VL 39       
03.29.12 - VL UD        CD4 640
_-_-_-_-_-_-_-_-_-_-_-_-_-_-_-_-_-_-_
Truvada.Norvir.Prezista - Serostim HGH

Online Ann

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Re: Both Partners Positive...Will Have Same Genotype?
« Reply #1 on: January 16, 2010, 01:05:00 PM »
Yes, if one or the other of you were the source of infection of the other, then you will have the same genotype. My partner, from whom I acquired my virus, and I have the same genotype.

If there is resistance that came with the initial infection, then both will have the same resistance. If there is resistance resulting from one partner having a failed combo, then only that partner will have that resistance. There is some evidence that a partner can be re-infected with the resistant virus, but this only seems to happen when a person is newly infected (first two years or so) in the first place. And it doesn't really seem to happen in long-term monogamous partners.

If you're asking about this because you want to do away with condoms, you'll have to decide that for yourself but I can tell you that my bf and I do not use them and we have no problems. He's on meds, I'm not, and neither of us have resistance issues.

Hope that helps.

Ann
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Offline madbrain

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Re: Both Partners Positive...Will Have Same Genotype?
« Reply #2 on: January 16, 2010, 02:05:28 PM »
Question... If both partners are positive, and they both became positive from one another, don't know who was positive first (it really doesn't matter, I'm working on learning how not to give disclosure of "I dont know who had it first" since it really is irrelevant based on the fact that we are both positive) I'm sure some here can relate to these questions that when we were negative we would often ask of a positive person but now that we are on the other side of the fence, we truly understand how irrelevant these questions can be because it changes nothing, it does not take the virus away..... I've shifted from my question, venting! Here we go again....

Both partners positive, became positive from one another, will the virus Genotype? Strain? (new to all this terminology) be the same? Exactly the same?  Same Drug Resistance? I would assume it would be but I do not know and don't trust too much of what I Google.....

Thanks!!!

Guy

Yes, the genotype should be the same in this case. My partner and I both tested positive at the same time, and the genotypes were the same. We are not 100% sure who had it first, but based on our sexual histories it is more likely that he contracted it from me. He has been on meds for almost 3 years, and I'm not yet.

However, the virus can mutate over time and so if the tests are repeated, it's possible the genotypes would diverge, especially if the partner on meds misses too many doses.

Offline 1228GUY

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  • Posts: 64
Re: Both Partners Positive...Will Have Same Genotype?
« Reply #3 on: January 16, 2010, 05:15:33 PM »
Thank you Ann/Madbrain. It's not so much due to sex w/no condoms but just wanting to know, I guess wanting to be a step ahead.  I get labwork this week then wait for numbers and see where I'm at.  Will keep you guys posted.
12.28.09 - Rcvd call I should test
12.29.09 - Confirmed
01.19.10 - VL 30015  CD4 172
03.18.10 - VL 1627    CD4 193
04.15.10 - VL 965      CD4 248
07.09.10 - VL 227      CD4 233 (19%)
08.12.10 - VL 99        CD4 280 (18%)
12.03.19 - VL 79        CD4 262 (21%)
02.09.11 - VL 90        CD4 376 (19%)
05.20.11 - VL 106      CD4 196 (25%)
06.23.11 - VL 82        CD4 289
08.05.11 - VL UD       CD4 286
11.04.11 - VL 54        CD4 305
03.02.12 - VL UD       CD4 523
04.30.12 - VL 74
08.12.12 - VL 153      CD4 353
11.15.12 - VL 43        CD4 443
01.11.13 - VL 39       
03.29.12 - VL UD        CD4 640
_-_-_-_-_-_-_-_-_-_-_-_-_-_-_-_-_-_-_
Truvada.Norvir.Prezista - Serostim HGH

Offline John2038

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Re: Both Partners Positive...Will Have Same Genotype?
« Reply #4 on: January 17, 2010, 01:12:32 PM »
Effect of Antiretroviral Therapy on Risk of Sexual Transmission of HIV Infection and Superinfection

The questions answered are:

Prevention of Sexual Transmission of HIV: Individual Couples vs. Populations
What is the Risk of Sexual HIV Transmission for HIV-infected Persons With Undetectable Viral Load?
The Meaning of “Undetectable” Viral Load: Persistence of Virus in Plasma and Seminal Fluid
Transient Increases (“Blips”) in Viral Load
Correlation Between Plasma and Genital Fluid Viral Load and Resistance to ART
ART as a Prevention Tool for Sexual Transmission of HIV
When Both Partners are Infected: What is the Significance of Superinfection in HIV Transmission?
CDC Guidance on ART and its Effect on Sexual Transmission of HIV


http://www.cdc.gov/hiv/topics/treatment/resources/factsheets/print/art.htm

 


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