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Author Topic: Name-Brand drugs VERSUS new generic replacements. Is there a skimp in quality?  (Read 1333 times)

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Offline Rendog

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  • Posts: 2
As old drug patents begin to expire on name-brands, and their cheaper generics rush in to replace them, are  we forced to sacrifice the integrity of our quality-controlled regimine for inferior parts made in China, just because our Insurance Provider has an eye on the bottom line and decides to forgo the original?

Part of my cocktail therapy includes Bristol-Myers Squibb's VIDEX EC which has now gone generic: didanosine. It's been good drug therapy . . . longterm, compatible and effective. That's why it's traumatic to me when my Provider recently notified me that they're removing it from formulary, trying to bully me into the cheaper generic.

I do not ascribe to the belief that all generics are like their originals, especially when it involves crucial AIDS anti-retrovirals. My doctor agrees with me and we're appealing with my Insurance Provider for an exception: prior auth.  I don't foresee a problem.

Nevertheless, has anyone else dealt with this issue? Has anyone else been happy on a generic replacement, finding no difference at all?  I'd like to hear from all sides of this issue, if you'd care to share.  Thanks.

 :-\

Offline leatherman

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  • Google and HIV meds are Your Friends
Part of my cocktail therapy includes Bristol-Myers Squibb's VIDEX EC which has now gone generic: didanosine.
didanosine has already been generic for easily 4 or 5 years now.

I've been taking it in OH and now SC for all those year and didn't notice any difference at all in side effects or effectiveness. ;)
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Oh my friends, my friends forgive me
That I live and you are gone.
There's a grief that can't be spoken.
There's a pain goes on and on.
Empty chairs at empty tables
Where my friends will meet no more.

"Empty Chairs at Empty Tables" from Les Miserables

Offline Matty the Damned

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  • Posts: 12,160
Matty the Damned doesn't know how it works in the rest of the world, but here in Oz generic drugs must be bio-equivalent to their brandname counterparts.

MtD

Offline Ann

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  • It just is, OK?
    • Num is sum qui mentiar tibi?

Matty the Damned doesn't know how it works in the rest of the world, but here in Oz generic drugs must be bio-equivalent to their brandname counterparts.


Same here in the UK.

One of the meds I take (non-hiv) is a generic. While I see absolutely no difference in efficacy, one of the generic brands (it varies from month to month) I don't care for. They come in blister strips and they tend to crumble around the edges a bit when I pop them out. Very annoying. I complained to my pharmacy a few months ago and I haven't had that brand since. (now watch, just because I said that I'll get them next time I fill my script. ::)  )
Condoms are a girl's best friend

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"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline mecch

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  • Posts: 10,732
  • red pill? or blue pill?
Its a good question.
If "first world" HIV+ patients are to be eventually treated with generic drugs - where will these be produced. There are reputable big pharma companies that produce generic drugs and reputable pharma companies in developing countries that produced patented drugs and generics and everthing goes well if its all on the up and up.  The other day a HUGE load of fake drugs was seized in Geneva. Not generic - FAKE - frauds.  Now you would think swiss pharmacies would not be buying fake drugs cause there is universal coverage here and also because Pharmas make money for the economy here.

In years in which I had no insurance, or just for off-label use, I've bought drugs in reputable pharmacies in Mexico, Egypt, Spain etc. that ordinally I would have needed scripts for in Swiss, UK, USA. 

I personally would feel a bit quesy about where a HIV generic was coming from and who was controlling it.  As long as you can trust the system I think its fine.

But as time progresses, whats to say we wont have a repeat of the food poisoning and chemical poisoning we have seen in recent food and consumer goods in China.

This is not a slight on China.  Do you know China has a very advanced organic farming production. But you are NOT getting the delicious chinese organic asparagus in the little cheap jars of chinese import asparagus at the Boston corner grocery store. 

“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline veritas

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  • Posts: 1,408
Rendog,

Usually there is no difference in efficacy. Generic drugs are cheaper because the manufacturer did not have to  pay for the discovery end of the drug. See this:

 http://www.medicinenet.com/script/main/art.asp?articlekey=46204

Generics can be a good option.

v

Offline leatherman

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  • Posts: 5,920
  • Google and HIV meds are Your Friends
While I see absolutely no difference in efficacy, one of the generic brands (it varies from month to month) I don't care for. They come in blister strips and they tend to crumble around the edges a bit when I pop them out. Very annoying. I complained to my pharmacy a few months ago and I haven't had that brand since. (now watch, just because I said that I'll get them next time I fill my script. ::)  )
I take acyclovir (non-hiv) daily and recently had the same issue. :D The regular generic tablet is a slick-coated blue tab which slides down my throat nicely. The newer generic is an uncoated slightly larger white tablet, that can get easily "stuck" in the dip of your tongue and immediately begins to melt. My case mgr and I were chatting with the pharmacy and mentioned this. My next shipment came in a double-sized bottle. Now it's in caplets, which are even larger yet AND half stremgth, so I have to take twice as many!! ::) :o I'm not saying anything about my meds ever again. ROFL ;D
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Oh my friends, my friends forgive me
That I live and you are gone.
There's a grief that can't be spoken.
There's a pain goes on and on.
Empty chairs at empty tables
Where my friends will meet no more.

"Empty Chairs at Empty Tables" from Les Miserables

Offline Ann

  • Administrator
  • Member
  • Posts: 27,947
  • It just is, OK?
    • Num is sum qui mentiar tibi?
I take acyclovir (non-hiv) daily and recently had the same issue. :D The regular generic tablet is a slick-coated blue tab which slides down my throat nicely. The newer generic is an uncoated slightly larger white tablet, that can get easily "stuck" in the dip of your tongue and immediately begins to melt. My case mgr and I were chatting with the pharmacy and mentioned this. My next shipment came in a double-sized bottle. Now it's in caplets, which are even larger yet AND half stremgth, so I have to take twice as many!! ::) :o I'm not saying anything about my meds ever again. ROFL ;D

Ew, yeah, one of the generic acyclovir brands I get sometimes is big, round and really chalky and sticks in my throat if I'm not careful. The one I most usually get is oval and has a coating so it slides easily. I've never had blue generic acyclovir, they're always white.
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

 


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