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Author Topic: Question for all  (Read 1872 times)

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Offline tommy246

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Question for all
« on: September 03, 2009, 03:03:22 PM »
I expect some very different awnswers to this  but out of intrest what is your general opinion on time scales for a possible cure or how long before we have almost side effect free meds
jan 06 neg
dec 08 pos cd4 505 ,16%, 1,500vl
april 09 cd4 635 ,16%,60,000
july 09 ,cd4 545,17%,80,000
aug 09,hosptal 18days pneumonia cd190,225,000,15%
1 week later cd4 415 20%
nov 09 cd4 591 ,vl 59,000,14%,started atripla
dec 09  cd4 787, vl 266, 16%
march 2010  cd4 720 vl non detectable -20  20%
june 2010  cd4  680, 21%, ND

Offline sensual1973

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Re: Question for all
« Reply #1 on: September 03, 2009, 03:22:29 PM »
i dont think a cure will ever be available in our life time.
and i have never heard of meds free of side effects,wether its hiv meds or other illnesses.
God grant me the serenity to accept the things i can not change.

Offline mecch

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  • red pill? or blue pill?
Re: Question for all
« Reply #2 on: September 03, 2009, 03:51:24 PM »
I think scientists can predict with more knowledge about when there will be a cure.

You asked time to a "possible cure".
I assume you mean, time to a cure, period.?
There are possible cures ever since tritherapy.  Every year.  t

The big cheeses talk about functional cures..

I think HEP C is the only virus that has ever been "cured".  Correct?

I dont invest myself too much in this research forum but it is good to hope and think what is possible.  Just from what I have gleaned here and there lately, it seems like immune boosting vaccines will come along soon enough and maybe we'll get relief from so much drugs...  What do you think?

Every doc I have spoken to in Switzerland swears up and down that, becoming HIV+ these days means that AIDS is never going to kill you.  As we understood "AIDS" up to recently.

I think in the next ten years there will be a radical redefinition of HIV and AIDS that most of the public will come to understand.  This is happening in the West already. 

With appropriate medical care and drugs, it almost seems that, in 10 years time, if HIV is related to sickness or death, it is from lifestyle choices once HIV+.   The doctors seem to be saying many possible hiv-or HAART-related complications, for recently infected, and maybe for LTS as well, can be avoided if you are careful about how you live.  All this assumes medical care and drug availability. 

I guess you want a straight answer about a total cure, but again, it seems we can get conjecture here.  Totally ignorant people can predict, moderately informed.  Majorly informed. Deluded.
Whouldn't we want reasoned statements from the people with the most knowledge to predict? Scientists.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline Assurbanipal

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Re: Question for all
« Reply #3 on: September 03, 2009, 04:32:26 PM »
I expect some very different awnswers to this  but out of intrest what is your general opinion on time scales for a possible cure or how long before we have almost side effect free meds

Many people find medication combos that do not cause significant side effects for them today -- not everyone but many.  And very few seem to report side effects on drugs like Isentress.  The really bad effects today are typically experienced by people who don't/didn't start drugs on a timely basis or were on previous generations of drugs.

So, for many, the answer is probably right now.  But we just don't know for sure.

Part of midlife is the recognition that life doesn't come wrapped up with guarantees anyway and that we are all going to die of something some day.  So we have to accept some uncertainty with HIV drugs and everything else that we deal with in our lives and enjoy the life we have.

I think HEP C is the only virus that has ever been "cured".  Correct?
Smallpox (variola virus) was eradicated in the world population.  That's one definition of cure.
But if you mean whether people can be cured of a viral infection -- well people get over colds (adenovirus infections) all the time.
5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%

Offline confidentIwillbeOK

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Re: Question for all
« Reply #4 on: September 03, 2009, 11:21:09 PM »
Not a prediction but my ID doctor believes that if we ever have a cure we will have it within 10 years.  His belief is that because so much time, money, and expertise has been poured into research that if a cure is attainable we will have it within 10 years.  My personal (& uneducated) opinion is that there will be a cure someday but that day could be 0-25 years out.  I do think, as others have posted, that treatment could become so much better in the years to come that it could almost seem as though there is a cure.  No matter what happens I am hopeful that every year we continue to have progress.  I would hate to think that what we have today is it. 

Offline AndyArrow

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Re: Question for all
« Reply #5 on: September 04, 2009, 03:13:47 AM »
The doctors seem to be saying many possible hiv-or HAART-related complications, for recently infected, and maybe for LTS as well, can be avoided if you are careful about how you live.

As a LTS I find this rather an offensive supposition. 

As if my lifestyle choices after I became HIV+ led to certain med failures in the past or the thrush & CMV infection in my esophagus.  Since there are so few LTS (and I'm a relative newbie at 15yrs) the long term effects of the virus are just now being studied.

And to the OP -  Taking Truvada, Prezista, Norvir, Isentress I have very few side effects compared to past drug combos.  So a cure ... no time soon.  Drugs with very few side effects are out there depending on what you can take and what your body can tolerate.

AA
« Last Edit: September 04, 2009, 03:16:56 AM by AndyArrow »
It is not the arrival that matters.  It is the journey along the way. -- Michel Montaigne

Offline mecch

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  • red pill? or blue pill?
Re: Question for all
« Reply #6 on: September 04, 2009, 06:10:20 AM »
I didn't know how to word that, in not too too many words, to not offend LTS.  Sorry if I did, it was not intentional.  When LTS (now) once had, or still have, damages to health from then, before HAART or with crappy HAART.  Many damages in such conditions have nothing to do with life-style choices, duh, it was the virus.  

the question is simplified, the answers may be too.
« Last Edit: September 04, 2009, 06:12:49 AM by mecch »
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline AndyArrow

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Re: Question for all
« Reply #7 on: September 05, 2009, 08:40:53 AM »
I didn't know how to word that, in not too too many words, to not offend LTS.  Sorry if I did, it was not intentional.  When LTS (now) once had, or still have, damages to health from then, before HAART or with crappy HAART.  Many damages in such conditions have nothing to do with life-style choices, duh, it was the virus. 

the question is simplified, the answers may be too.

Nor did I think you intended it to be offensive but I wanted to point out how off the cuff comments like that can be hurtful and more importantly (at least to me) lead to further stigmatization of LTSers.  As in "oh, if he wouldn't have just taken better care of himself none of that would have happened."

My other point being that while the virus is suppressed it appears from everything I've read that it is still doing damage throughout the body although at a much slower pace but exactly what and how is still being studied because in scientific terms HIV is still relatively new.

Edited to Add -- Sorry for the hijack tommy, I hope you get a lot more answers & dialogue going.
« Last Edit: September 05, 2009, 08:43:30 AM by AndyArrow »
It is not the arrival that matters.  It is the journey along the way. -- Michel Montaigne

Offline mousey

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Re: Question for all
« Reply #8 on: September 15, 2009, 01:19:29 PM »
I don't see a possible outcome in a cure for the next following 5-10 years. But I will be one of the millions who will be extremely happy if one day I will still be alive to know that a cure has been found. 

Life is great and treasure every minute and second. Remember your meds and listen to your doctor. Have fun and enjoy what you are doing now and have no regrets. You will never know what will happen tomorrow.
:: Believe in a cure ::

Offline veritas

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  • Posts: 1,410
Re: Question for all
« Reply #9 on: September 15, 2009, 02:29:05 PM »

Tommy,

Martin Delaney (aids activist) said it best:

“Far too many people with HIV, as well as their doctors, have accepted the notion that a cure is not likely. No one can be certain that a cure will be found. No one can predict the future. But one thing is certain: if we allow pessimism about a cure to dominate our thinking, we surely won’t get one… We must restore our belief in a cure and make it one of the central demands of our activism.”11

Research is ramping up, millions of dollars are going into the Global Aids Initiative, potential advances (gene therapy, anti-ps (my pet), powerful broadly neutralizing antibodies etc.) are coming together to perhaps lead in the right direction. The wait seems interminable. But remember Sen. Kennedy's words:
"The work goes on, the cause endures, the hope still lives, and the dream will never die!"

Never give up!

v

 


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