Quantcast

Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
August 28, 2014, 11:31:51 PM

Login with username, password and session length


Members
Stats
  • Total Posts: 636506
  • Total Topics: 48311
  • Online Today: 258
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: effective treatment hiv anti-CTLA4 - MDX-1106?  (Read 2137 times)

0 Members and 1 Guest are viewing this topic.

Offline brazilianman

  • Member
  • Posts: 92
effective treatment hiv anti-CTLA4 - MDX-1106?
« on: July 07, 2009, 04:02:40 PM »
 ??? ??? ???the two antibodies already exist, need not be manufactured. has proved safe in tests on humans. Why not test HIV positive in humans? ??? ??? ???

Offline brazilianman

  • Member
  • Posts: 92
Re: effective treatment hiv anti-CTLA4 - MDX-1106?
« Reply #1 on: July 07, 2009, 06:45:14 PM »
pipeline medarex

Strategic Assets in Clinical Development

Product Candidate Indication Clinical Status Partner/Licensee
Ipilimumab
anti-CTLA4
Melanoma, Prostate Cancer, Lung Cancer and Others  Phase 3 and earlier Bristol-Myers Squibb
Co-promote/Profit share
MDX-1100
anti-IP10 Ulcerative Colitis, Rheumatoid Arthritis Phase 2 Wholly-owned
 
MEDI-545 and MEDI-546
anti-IFNα Pathway Lupus and Autoimmune Diseases Phase 2 and earlier MedImmune/AstraZeneca
Co-promote option
MDX-1342
anti-CD19 Chronic Lymphocytic Leukemia, Rheumatoid Arthritis Phase 1 Wholly-owned
 
MDX-1106 (ONO-4538)
anti-PD1 Cancer, Hepatitis C Phase 1 Ono Pharmaceutical
Co-development
MDX-1105
anti-PD-L1 Cancer Phase 1 Wholly-owned
 
MDX-1401
anti-CD30 Hodgkin Lymphoma Phase 1 Wholly-owned
 
MDX-1411
anti-CD70 Cancer Phase 1 Wholly-owned
 
MDX-1203
anti-CD70 Antibody-Drug Conjugate Cancer Phase 1 Wholly-owned
 
ValortimTM (MDX-1303)
anti-B. anthracis PA Anthrax Infection Phase 1 PharmAthene
Co-development

Selected Financial Assets in Late-Stage Clinical Development

Product Candidate Indication Clinical Status Partner/Licensee
STELARATM (ustekinumab)
anti-IL12/IL23 Psoriasis Approved in Canada and Europe Centocor Ortho Biotech
Milestones/Royalties
SIMPONITM (golimumab)
anti-TNFα Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis Approved in Canada and U.S. Centocor Ortho Biotech
Milestones/Royalties
Ilaris® (canakinumab)
anti-IL1β Cryopirin-associated Periodic Syndromes Approved in U.S. Novartis Pharma
Milestones/Royalties
Ofatumumab (HuMax-CD20)
anti-CD20 Chronic Lymphocytic Leukemia, Rheumatoid Arthritis BLA/MAA Filed Genmab/GlaxoSmithKline
Equity Interest
Zalutumumab (HuMax-EGFR)
anti-EGFR Head and Neck Cancer Phase 3  Genmab
Equity Interest
MDX-066 (CDA-1) +
MDX-1388 (CDA-2)
anti-C. difficile Toxin A and Toxin B C. difficile Infection Phase 2 Merck & Co.
Co-development
« Last Edit: July 07, 2009, 06:47:16 PM by brazilianman »

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.