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Author Topic: Is Atripla imunity booster or Viral load reducer?  (Read 2042 times)

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Offline metekrop

  • Member
  • Posts: 351
Is Atripla imunity booster or Viral load reducer?
« on: April 09, 2010, 03:15:24 PM »
I just want to know what the magic Atripla is doing.  I was taking both the Atripla and bacterium.  Atripla daily and continuously but bacterium for about two week.  If I correctly remember my doctor prescribed me bacterium to reduce my VL.  But at the same time both my CD increased and my VL became undetectable.  What effects which one? am just curious.  :o
« Last Edit: April 09, 2010, 03:17:50 PM by metekrop »
Diag on Dec 8, 2000, CD 440 VL 44K, No Meds
Dec/08 - Feb/09 CD< 50 & VL >500k hosp'z.
St. Atripla - July/09 CD 179, VL 197k
Oct/09 CD 300 VL UD Chol 267
Mar/10 CD 468 UD, Ch 220
Aug/10 CD 460 UD, Ch 195
Dec/10 CD 492 UD, Ch 172
Mar/11 CD 636 UD, Ch 201
Aug/11 CD 530 UD, Ch 98
Jan/12 cd 616 UD, ch 189
Jul/12 CD 640 UD, Ch ?
Dec/12 CD 669 Ud, Ch 125
May/7 CD711 Ud, Ch?
Nov/ 22 663 UD, Ch,

Offline Rev. Moon

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  • Posts: 3,782
  • Smart ass faggot
Re: Is Atripla imunity booster or Viral load reducer?
« Reply #1 on: April 09, 2010, 03:33:49 PM »
If I correctly remember my doctor prescribed me bacterium to reduce my VL.

The Bactrim is not taken to reduce your viral load; it would have been prescribed due to your low CD4 (under 200) in order to prevent pneumocystis pneumonia (PCP).

The improvement that you have experienced has been thanks to the HAART, and I must say that you have indeed responded quite nicely.  Keep it going.
"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

Offline leatherman

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  • Google and HIV meds are Your Friends
Re: Is Atripla imunity booster or Viral load reducer?
« Reply #2 on: April 09, 2010, 05:23:56 PM »
HAART (Atripla in your case) destroys HIV, hence reducing the viral load. No meds affect your cd4s per se, they are what they are (and they fluctuate throughout not only the month, but hour to hour). However, when the viral load of HIV is reduced and quits killing off the cd4s (by hijacking them to reproduce itself), those immune system cells have a chance to recover and you see the cd4 rise (sometimes a little, sometimes a lot)

The Rev is correct. Bactrim is an antibiotic, not an antiretroviral, and is used to prevent PCP when your tcells are so low (<200) that your own immune system cannot keep the in check the fungus, commonly found in healthy lungs, that causes PCP
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Oh my friends, my friends forgive me
That I live and you are gone.
There's a grief that can't be spoken.
There's a pain goes on and on.
Empty chairs at empty tables
Where my friends will meet no more.

"Empty Chairs at Empty Tables" from Les Miserables

Offline Boo Radley

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  • Not a "real man" and damn proud, mithter... FAB
    • Animal Rescue New Orleans
Re: Is Atripla imunity booster or Viral load reducer?
« Reply #3 on: April 09, 2010, 06:40:05 PM »
HAART (Atripla in your case) destroys HIV, hence reducing the viral load...

I thought HAART worked by disabling parts of the virus used to invade many of the cells it invades.  The decrease in blood vl reflects HIV's inability to infect cells and multiply, not the literal destruction of the virus.   The blood vl also doesn't necessarily reflect vl in other parts of the body.  

P.S.  Atripla is also a great dessert topping...
String up every aristocrat!
Out with the priests and let them live on their fat!





Everything I do, say, think, excrete, secrete, exude, ooze, or write 2007 Sweet Old Boo, Inc.

Offline J.R.E.

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  • Posts: 6,962
  • Joined Dec-2003 Living positive, since 1985.
Re: Is Atripla imunity booster or Viral load reducer?
« Reply #4 on: April 09, 2010, 09:58:23 PM »
I thought HAART worked by disabling parts of the virus used to invade many of the cells it invades.  


That's the way I always understood it.   To the original poster, here's a short video explaining the actions of NNRTI's.  In this case,  Viramune ( Nevirapine)  You may want to smoke a joint first !

Atripla contain Sustiva (NNRTI) and two NRTI's ( Viread and Emtriva)


http://www.youtube.com/watch?v=RUUyd5bE9vQ


Ray
« Last Edit: April 09, 2010, 10:07:20 PM by J.R.E. »
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of DEC 9th, 2013,  t-cells are at 437 Viral load  <40 .

 Current % is at 16% (L)

  
 62 years young.

Offline Rev. Moon

  • Member
  • Posts: 3,782
  • Smart ass faggot
Re: Is Atripla imunity booster or Viral load reducer?
« Reply #5 on: April 09, 2010, 10:58:59 PM »

That's the way I always understood it.   To the original poster, here's a short video explaining the actions of NNRTI's.  In this case,  Viramune ( Nevirapine)  You may want to smoke a joint first !

Atripla contain Sustiva (NNRTI) and two NRTI's ( Viread and Emtriva)


http://www.youtube.com/watch?v=RUUyd5bE9vQ


Ray

Correct.  If you wiki the meaning of HAART you get a brief (though perhaps confusing to the average reader) description of what the different classes (of meds) do in order to prevent viral replication:

http://en.wikipedia.org/wiki/Haart



Quote
Illustration of (1) the virus entering the cell, (2) conversion of viral RNA to DNA using the reverse transcriptase enzyme, (3) incorporation of the viral genome into the DNA of the host cell, (4) viral proteins cleaved by protease for assembly of new viral particles, and (5) new virus particles budding from the surface of the host cell. It also shows the steps in the viral life cycle that are interrupted by (A) fusion inhibitors (B) reverse transcriptase inhibitors and (C) protease inhibitors. Source: National Institutes of Health.
"I have tried hard--but life is difficult, and I am a very useless person. I can hardly be said to have an independent existence. I was just a screw or a cog in the great machine I called life, and when I dropped out of it I found I was of no use anywhere else."

 


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