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Author Topic: Maybe not Atripla-- truvada/reyataz/norvir?  (Read 1739 times)

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Offline Broch

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Maybe not Atripla-- truvada/reyataz/norvir?
« on: February 16, 2009, 09:09:39 PM »

I am researching the truvada/reyataz/norvir option to atripla.

Any side effects I should know about?
Anyone want to comment on protease inhibitors vs. non-nucs?

Offline mecch

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Re: Maybe not Atripla-- truvada/reyataz/norvir?
« Reply #1 on: February 16, 2009, 09:38:21 PM »
Don't experts say they are both first line greatly effective combos? Side effects:  6 of 1, half dozen of another. Maybe none!  Hope you find the one that works well for you.
“From each, according to his ability; to each, according to his need” 1875 K Marx

Offline a2z

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Re: Maybe not Atripla-- truvada/reyataz/norvir?
« Reply #2 on: February 16, 2009, 10:19:02 PM »
I've had relatively few effects on Truvada/Reyetaz/Norvir, which is the only combo I have ever taken (I started on meds in October.)

Some pain in the ankles and feet, which went right away after I started taking Glucosamine/Condroiton suppliments for a week, and then discontinued them.  (Neuropathy?)
Some loss of energy
Increase in my allergies (which might account for the loss of energy, as my body is constantly fighting those upper respiratory infections.)
Some yellowing at times

And that's it.  Nothing that put my life or job in jeopardy.  No dizziness, no puking, no general nasuea, no difficulty in operating a vehicle.

Dates are blood draw dates:
3/12/15: CD4 941, 36.4%, VL UD
9/4/14: CD4 948, 37.9%, VL 150
5/23/14: CD4 895 --.-% VL UD - Truvada/Isentress
09/21/09: CD4 898 27.0% VL 120 - back on track, same meds.High level enzymes, but less so
06/15/09: CD4 478 21.8% VL 1150 - high liver enzymes... looks like I may not be resistant
05/22/09: Fixed insurance, resumed medicine
04/17/09: Ran out of medicine, could not resolve insurance problems
04/01/09: CD4 773 28% VL 120 - high liver enzymes
12/01/08: CD4 514 23% VL 630
10/17/08 started Reyataz, Norvir and Truvada. -- possibly minor neuropathy, but otherwise okay.
9/10/08: CD4 345 17%, VL > 78K
8/18/08: CD4 312 18%, VL > 60K (considering meds)
12/19/07: CD4 550 28% VL > 100K (no meds yet)
Diagnosed 10/23/07

Offline Inchlingblue

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Re: Maybe not Atripla-- truvada/reyataz/norvir?
« Reply #3 on: February 20, 2009, 09:03:32 PM »
Are you starting treatment or switching? I have not yet started and based on ALOT of research on the subject (and no resistance issues) I've come to the conclusion that Isentress/Truvada is the best way to go (in  my humble opinion). Issentress has performed very well head to head with Sustiva (both with Truvada) and is expected to be approved for first line therapy sometime this year.

Truvada/Reyataz/Norvir and Epzicom/Reyataz/Norvir (Epzicom best with VL under 100K) are also very good. I think it comes down to what do you prefer, having to take your meds with a full nutritious meal, which you have to do with Reyataz or having to take meds twice a day (which you have to do with Isentress, although once daily dosage might be available in the near future).


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