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Author Topic: I have a question for the community!  (Read 1902 times)

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Offline Enigmadave

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  • Posts: 3
I have a question for the community!
« on: February 09, 2009, 07:26:09 AM »
I was originally diagnosed in 2000 with a CD4 of 0 and my VL off the charts. I have been on the same drug regimen since being diagnosed. I just changed Dr. and one of the things they recommended was to change from my current meds(Zidovudine, Ziagen, and Sustiva) to Epzicom, Truvada, and Sustiva.
 My CD4 is 618 and I have been undetectable for nearly 6 years.  From what I have read, the only reason for changing my current regimen would be for the convenience of only taking the meds at night instead of a morning/bedtime regimen.
 I also worry about having to deal with side effects of the new regimen! I have little or no side effects from my current and wonder if the change would raise my CD4 more or would just be a negligible convenience of taaking the meds at bed.
 Anyone out there have any feedback? I am curious for others take on my dilemma!


Offline J.R.E.

  • Member
  • Posts: 7,498
  • Joined Dec-2003 Living positive, since 1985.
Re: I have a question for the community!
« Reply #1 on: February 09, 2009, 08:06:02 AM »
Hello Dave,

The combination that is suggested makes no sense to me. As far as I can tell from your post, the AZT is being dropped.

They are suggesting Epzicom ( which is a combination of Epivir and Ziagen) . They also want Truvada added, which is another combination of two drugs ( Viread and Emtriva.)

Emtriva and Epivir ( I believe) should never be used together !!

With this combination that is being suggested to you, it would put you on 1 non-nuke, and 4 nukes.

This doesn't sound right to me. But I will let the experts chime in here, and offer their suggestions.

Take care---Ray
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 25 mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg






Diagnosed positive in 1985,.. In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started on  HAART on October 24th, 2003.

 As of 9/16/16,  t-cells are at 501,   Viral load remains <40

Current % is at 12%

 64 years young.

Offline Peter Staley

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  • Founder & Advisory Editor, AIDSmeds.com
    • AIDSmeds.com
Re: I have a question for the community!
« Reply #2 on: February 09, 2009, 08:11:50 AM »
Dave -- ditto what Ray has said.  You must have misheard the new, recommended regimen.  Epzicom is two drugs in one pill -- Ziagen and Epivir.  And Truvada is also two drugs in one pill -- Viread and Emtriva.  So you wouldn't take both of these, plus Sustiva -- that would be FIVE antivirals (way more than you need).

I'm betting your doc suggested switching to Truvada + Sustiva, OR Epzicom + Sustiva.  Most folks take Truvada instead of Epzicom because it has been shown to have fewer side effects.

Even better news..  Truvada + Sustiva has been combined into one pill called Atripla, so you'd only have to take one pill, once a day (at night).  And you'd only have to pay one co-pay at the pharmacy (saving you $$$).

Welcome to our forums!


Offline aztecan

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  • Posts: 5,512
  • 31 years positive, 59 years a pain in the butt
Re: I have a question for the community!
« Reply #3 on: February 09, 2009, 11:03:06 AM »
Hey Dave,

Ray and Peter hit it as far as the regimen you brought up.

The only major switch is the dropping of Zidovudine for another med, as Peter said, Truvada or Epzicom coupled with Sustiva.

If you are switching for convenience, I would probably go with Atripla. But, if the twice a day regimen doesn't bother you, I really don't see any reason to switch.

I think another doctor visit and a heart to heart, or should that be HAART to HAART  ;) with the doc might be in order.



« Last Edit: February 09, 2009, 11:07:57 AM by aztecan »
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline Enigmadave

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  • Posts: 3
Re: I have a question for the community!
« Reply #4 on: February 10, 2009, 07:27:12 AM »
Thank you for the feedback!!


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