Quantcast

Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
April 18, 2014, 08:06:13 PM

Login with username, password and session length


Members
  • Total Members: 22215
  • Latest: chuff
Stats
  • Total Posts: 620285
  • Total Topics: 46733
  • Online Today: 254
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: U took any monoclonal antibody for any disease PLEASE POST experience  (Read 933 times)

0 Members and 1 Guest are viewing this topic.

Offline bimazek

  • Member
  • Posts: 781
If U have taken any monoclonal antibody to treat any disease-- usually a cancer, or transplant rejection or auto immune, or T cell CD3 Receptor inhibitor, or Respiratory Syncytial Virus (RSV) or  lymphoma, etc see complete list below then PLEASE POST -your experiences with these meds only if you had hiv at the time, i am curious about the effect on how you felt, your body, cd4 counts up or down, did doctor say anything about them being good or bad regarding hiv infection.

I have not seen any info and am curious to hear peoples first hand experience, supposedly they are tolerable for general population

Did you have any good or bad experiences on them, were you on HAART at the time or was it before you started haart

all these drugs end in letters...... mab  for example  Abciximab,


mab

FDA-approved therapeutic monoclonal antibody

FDA approved therapeutic antibodies

The first FDA-approved therapeutic monoclonal antibody was a murine IgG2a CD3 specific transplant rejection drug, Muromonab (OKT-3), in 1986.  Currently, twenty-one FDA-approved therapies exist, and hundreds of therapies are undergoing clinical trials. Most are concerned with immunological and oncological targets.

FDA approved monoclonal antibodies

Antibody     Brand name     Approval date     Type     Target     Approved treatment(s) 

Abciximab   ReoPro   1994     inhibition of glycoprotein IIb/IIIa   Cardiovascular disease

Adalimumab   Humira   2002    inhibition TNF-a Inflammatory diseases (auto-immune disorders)

Alemtuzumab   Campath   2001   humanized   CD52   Chronic lymphocytic leukemia

Basiliximab   Simulect   1998   chimeric   IL-2 receptor a   Transplant rejection

Bevacizumab   Avastin   2004   humanized   vascular endothelial growth factor   Colorectal cancer

Cetuximab   Erbitux   2004   chimeric   epidermal growth factor receptor   Colorectal cancer

Daclizumab   Zenapax   1997   humanized   IL-2 receptor a   Transplant rejection

Eculizumab   Soliris   2007   humanized   complement system protein C5   Inflammatory diseases including paroxysmal nocturnal hemoglobinuria

Efalizumab   Raptiva   2002   humanized   CD11a   acute myelogenous leukemia-linked to a cytotoxic agent, calicheamicin

(99mTc) Fanolesomab   NeutroSpec   2002   humanized   CD15   anti-CD15 antibodies bind selectively to neutrophils, it could be used to localize the site of an infection

Gemtuzumab   Mylotarg   2001   humanized   CD33   Inflammatory diseases (psoriasis)

Ibritumomab tiuxetan   Zevalin   2002   murine   CD20   Non-Hodgkin lymphoma (with yttrium-90 or indium-111)

Infliximab   Remicade   1998   chimeric   inhibition of TNF-a signalling   Inflammatory diseases (mostly auto-immune disorders)
111In-capromab   Erbitux   2004   chimeric   Prostate-specific antigen (PSA)   localize and stage a new or recurrent prostate cancer

Imciromab   Myoscint   1996   chimeric   myosin(in heart)   radioimmune conjugate - Indium In 111 imciromab pentetate-used for radiodiagnostic imaging of dead heart tissue
Muromonab-CD3   Orthoclone OKT3   1986   murine   T cell CD3 Receptor   Transplant rejection

Natalizumab   Tysabri   2006   humanized   T cell VLA4 receptor   Inflammatory diseases (mainly autoimmune-related multiple sclerosis therapy)

Omalizumab   Xolair   2004   humanized   immunoglobulin E (IgE)   Inflammatory diseases (mainly allergy-related asthma therapy)

Palivizumab   Synagis   1998   humanized   an epitope of the F protein of RSV   Viral infection (especially Respiratory Syncytial Virus (RSV)

Panitumumab   Vectibix   2006   human   epidermal growth factor receptor   Colorectal cancer

Ranibizumab   Lucentis   2006   humanized   vascular endothelial growth factor   Macular degeneration

Gemtuzumab ozogamicin   Mylotarg   2000   humanized   CD33   Acute myelogenous leukemia (with calicheamicin)

Rituximab   Rituxan, Mabthera   1997   chimeric   CD20   Non-Hodgkin lymphoma

Tositumomab   Bexxar   2003   murine   CD20   Non-Hodgkin lymphoma

Trastuzumab   Herceptin   1998   humanized   ErbB2   Breast cancer

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.