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Author Topic: Increased thirst and urination...Diabetes?  (Read 1323 times)

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Offline HollyStar

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  • Posts: 344
Increased thirst and urination...Diabetes?
« on: September 11, 2009, 12:59:55 AM »
Hi everyone,

I have been taking Lexiva and Truvada for about three weeks now. Pretty much right away I started to pee more often. Then I started to become thirsty pretty much all the time. I also take Acyclovir and sometimes I get dry mouth and thirsty for a while after taking it (I don't always drink as much water as I should with it). But now I'm thirsty almost all the time and last night I had to go to the bathroom three times, not including before I went to bed and when I got up in the morning. So I finally called my doctor today and he ordered urine and other tests for blood sugar and I'm not sure what else. I also have high cholesterol, I'm about 125 pounds. My doctor did mention the possibility of it being diabetes brought on by the medication but thought it odd with my build and weight. Has anyone else dealt with this? I tend to think that three weeks on the new regimen (I was on Atripla before) wouldn't bring on diabetes this fast, but I'm open to any information. Thanks.

Edited to add that the pamphlet information for the Lexiva does say to contact your doctor right away if you have increased thirst and urination, but it doesn't say why.
« Last Edit: September 11, 2009, 01:03:11 AM by HollyStar »
Diagnosed  July 28th 2003

'I don't want to get to the end of my life and find that I just lived the length of it. I want to have lived the width of it as well.' -Diande Ackerman

'Why not go out on a limb? Isn't that where the fruit is?' -Frank Scully

'If your ship doesn't come, swim out to it.' - Jonathan Winters

Offline newt

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  • the one and original newt
Re: Increased thirst and urination...Diabetes?
« Reply #1 on: September 11, 2009, 02:23:08 PM »
I would see my doc n get a glucose and urnine test as indeed you have

Lexiva can raise the level of glucose in your blood which leads to increased thirst etc. Long-term this *may* lead to insulin resistance ie diabetes so is worth looking at now. The build/weight thing is probably a red herring, this is almost certainly a genetic thing, ie you are built to react this way to this drug

Acyclovir can also occasionally lead to thirst, but on the pee front it is more typical with this drug to go less than usual

Tenofovir, one of the drugs in Truvada, can also lead to thirst and extra urination, the reason being its effects on your kidneys (which excrete the remainder of this drug when it's done with hammering the virus). It does not, though, increase your blood glucose as a rule.

As for speed, some people react fast to drugs, and sometimes it's a short-term reaction and resolves

Do drink more water

Hope this helps

- matt
"The object is to be a well patient, not a good patient"

Offline weasel

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  • Posts: 1,839
Re: Increased thirst and urination...Diabetes?
« Reply #2 on: September 11, 2009, 09:56:09 PM »
I pee like a tea pot  :o

I also drink  lots of water like    8   16 oz.  bottles a   day !

 drink lots of water !

 I have  found , I FEEL   like peeing but often only a drop pops out    :(

I often wake at night  ready to POP ......................   LOL

Life goes on ..............................

 hope you are OK , and will adjust fine !

                                              hugs , Carl
" Live and let Live "

Offline HollyStar

  • Member
  • Posts: 344
Re: Increased thirst and urination...Diabetes?
« Reply #3 on: September 12, 2009, 02:49:51 PM »
Yes, Newt, diabetes does run in the family. My older brother is a type 1 diabetic, so I wouldn't be surprised if I have the gene. Other than this problem that I've described here, I love the new regimen. It's just such a relief to be off the Atripla. I also had quite the reaction to Atripla in the beginning, so maybe this will resolve itself, at least I hope it does. Anyway, thank you so much for the info, I really appreciate it.

Weasel, I know what's it's like waking up feeling like you are about to pop. Good luck with that, lol. And yes, I will be drinking lots of water.
Diagnosed  July 28th 2003

'I don't want to get to the end of my life and find that I just lived the length of it. I want to have lived the width of it as well.' -Diande Ackerman

'Why not go out on a limb? Isn't that where the fruit is?' -Frank Scully

'If your ship doesn't come, swim out to it.' - Jonathan Winters


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