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Author Topic: I would like to switch from Atripla to ?  (Read 1596 times)

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Offline RCT474

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I would like to switch from Atripla to ?
« on: March 29, 2009, 01:12:31 AM »
What are some possible choices if I wanted to discuss a switch in HIV medication from Atripla to something else?  I have been on Atripla since March 2007.  My biggest concern is that I don't think that the Sustiva is working with my body right.  I do take this medication before I go to bed, however, I still get dizzy at times, and am suffering from severe fatigue.  I think that the Sustiva is the culprit.  Any thoughts or suggestions please?

Offline newt

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Re: I would like to switch from Atripla to ?
« Reply #1 on: March 29, 2009, 07:12:02 AM »
Atripla contains 3 meds - tenofovir, FTC and Sustiva (efavirenz).

Assuming you have no pre-treatment resistance, you have a wide choice. For example....

If you want to keep with a 1 x day dosing schedule, Reyataz (atazanavir) and Prezista (darunavir) are both once-daily options. Both these are from a class of drugs called PIs, and need 100mg of Norvir as a booster.

Isentress (raltegravir), an integrase inhibitor, is also an option. This is a newer drug, but shown as good as efavirenz in recent studies.

You can keep the tenofovir and FTC, they come in a handy once-daily tablet called Truvada.

Hope this helps as a starting point

- matt
"The object is to be a well patient, not a good patient"

Offline richva

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Re: I would like to switch from Atripla to ?
« Reply #2 on: March 29, 2009, 09:14:34 AM »
Sleep issues w/ Atripla forced me to switch meds after 8 months; should've done it sooner.  I kept the Truvada and added Reyataz/Norvir.  The 1x/dosing is great; only drawback is 3 co-pays vs. 1.  Within a few days, sleep cycle returned to normal, and my labs show same outcome as w/ Atripla.

08/1989 Acquired
04/1992 Diagnosed
03/25/2008 (YUP - 16 years later!) CD4 336/21% VL 217,000; started meds
08/2012 - Alive, living! and doing just fine, TYVM (w/ props to my doc, insurance carrier and Complera. I remember every day that I'm a lucky boy.)


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