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Author Topic: TMJ and Atripla  (Read 3920 times)

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Offline Imnew2this

  • Member
  • Posts: 36
  • I'm stronger because of it
TMJ and Atripla
« on: October 21, 2008, 10:42:06 PM »
I was wondering if anyone else has developed TMJ dysfunction (google it if you don't know) after starting on Atripla.  I've never had TMJ symptoms in the past, but since being on treatment for over six weeks now, I've had ongoing problems with jaw pain and dysfunction.  Not severe, just bothersome.  I am a healthcare provider myself and have studied as much literature as possible on each drug component, but haven't seen any reports of TMJ in any trials, etc.  I'm wondering if its more related to the dreams and stress, rather than the meds.  I'm just curious to see if anyone has experienced this.  If so, a report should be filed to Gilead and BMS as adverse reactions.  This is sometimes required with newer drugs.

Offline BreakerOneNine

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  • Posts: 65
    • Myspace
Re: TMJ and Atripla
« Reply #1 on: December 23, 2008, 10:32:47 PM »
I know I am late on this one...but I have recently been diagnosed with TMJ. I have been on Atripla for a year now. I don't know if the two are related but I never had TMJ before. It sucks too. It hurts bad. Anyone else having problems with TMJ?
poz 96 and med free til now.
Sept 2007 cd4 280 28.37% and VL 19,200
Nov 2007 cd4 230 25.87% and VL 38,000
Dec 2007 start Atripla
Jan 2008 cd4 490 32.5% and VL 119
Feb 2008 cd4 450 28.4% and VL less than 50
April 2008 cd4 510 28.6% and VL less than 48
July 2008 cd4 570 30.2% and VL less than 48
Dec 2008 cd4 570 32.0% and VL less than 48

Offline J.R.E.

  • Member
  • Posts: 7,120
  • Joined Dec-2003 Living positive, since 1985.
Re: TMJ and Atripla
« Reply #2 on: December 26, 2008, 07:13:03 PM »
I was wondering if anyone else has developed TMJ dysfunction (google it if you don't know) after starting on Atripla. 

I have never been on Atripla, so I can't comment on that. But I was diagnosed with TMJ, many years ago, long before starting on HIV meds, but it was also after being diagnosed positive on 1985.  I  can remember very well how painful it was !! It mostly affected my right side of my jaw, and it would shoot right up into my ear. I had to be very careful of what I ate, and how I chewed my food.  No jawbreakers for me !! It could trigger very easily. Some days the pain was totally unbearable. Heating pad, Ice packs, you name it I tried it.  I can't remember what I was prescribed for it back then. It wasn't a constant problem, only periodic. I also remember the popping and snapping sounds coming from my jaw.

The good thing is that after I started on HIV medication, in 2003, I haven't had any more problems with it. Go figure !

I hope you get some answers. Good luck. TMJ sucks big time!

Ray
« Last Edit: December 26, 2008, 07:15:02 PM by J.R.E. »
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 6/4/14,  t-cells are at 423, Viral load <40

 Current % is at 13% 

  
 62 years young.

Offline RWR

  • Member
  • Posts: 124
  • Nothing changes unless you change something
Re: TMJ and Atripla
« Reply #3 on: February 26, 2009, 05:38:34 PM »
I have been on Atripla for less than a year and have started having the clicking sore jaws.  I asked my Hiv Doctor about it but She said i need to talk to My VA Doctor about it. Am going to find a mouth guard to wear. A zanex seems to help it relax.
« Last Edit: February 26, 2009, 05:50:39 PM by RWR »
Hiv+ 1986
Isentress
Truvada

Bobby

Offline lonewolf

  • Member
  • Posts: 96
Re: TMJ and Atripla
« Reply #4 on: February 26, 2009, 07:20:08 PM »
Gulp,   Just started Atripla (as my first meds) about a week and a half ago.   Some side effects, but nothing going on with my jaw yet.  Sounds interesting,  hopefully time will tell of anything different with Atripla,  as it is one of the newer meds on the market.

Hope all goes well with you all, and your TMJ can be taken care of.

Bruce
"To all within the sound of my voice, I appeal: Learn with me the lessons of history and of grace, so my children will not be afraid to say the word “AIDS” when I am gone. Then, their children and yours may not need to whisper it at all."  Mary Fisher

Offline Imnew2this

  • Member
  • Posts: 36
  • I'm stronger because of it
Re: TMJ and Atripla
« Reply #5 on: February 27, 2009, 10:10:45 PM »
Funny, I had forgotten that I posted this back in October, but was just scanned some postings tonight and saw the responses.  My TMJ did get better in a few weeks, but again in the last week it has flared up again.  Like some others, I have no history of it prior to starting Atripla.  I'm going to discuss it with my doc next week and will report back if she has any insight.

Offline newt

  • Member
  • Posts: 3,878
  • the one and original newt
Re: TMJ and Atripla
« Reply #6 on: March 02, 2009, 03:00:27 PM »
It is perhaps worth noting that grinding your teeth when asleep on efavirenz seems to be a thing that happens to some people. My ex did it every night when he was on this drug.

- matt
"The object is to be a well patient, not a good patient"

Offline RWR

  • Member
  • Posts: 124
  • Nothing changes unless you change something
Re: TMJ and Atripla
« Reply #7 on: March 02, 2009, 03:11:17 PM »
Thanks Matt am going to find me a mouth guard for sleeping.      Bobby
Hiv+ 1986
Isentress
Truvada

Bobby

Offline notoutinilm

  • Member
  • Posts: 33
Re: TMJ and Atripla
« Reply #8 on: December 17, 2009, 06:57:49 PM »
Wonder if the original poster has any more news.  I am just starting week 3 of Atripla and the jaw/sinus thing just wont leave me alone.  I probably do have TMJ but it does not bother me at night, it kills about 12 hours after taking Atripla until I go to bed.  It is December so I find it hard to believe something outside has it in for me....

I am not grinding my teeth at night.  The other side effects are small compared to this.  I mentioned it to my doc's office and they said they did not think it is related.  I do!  I am bound and determined to for Atripla to work, so I am going to put up with it for two more weeks hoping things work out.  Just wondering if your bouts of jaw pain finally went away or what you wound up doing.

Thanks

Offline Gambit

  • Member
  • Posts: 24
Re: TMJ and Atripla
« Reply #9 on: February 18, 2010, 01:00:19 PM »
I know I'm digging up an old post.. but this is sort of my problem too.  No other side effects really from Atripla.. but the right side of my jaw is sore 24/7 (especially when I first wake up).  It hurts like hell to yawn, opening my mouth to take a bite of food is painful.  I'm going to ask my doctor about it on Thursday but I was surprised this post is the only thing I found when I googled it.
01-07-10 --- CD4 = 347 / VL = 19,000 / % = 23
02-09-10 --- Started Atripla
02-25-10 --- CD4 = 478 / VL = 260
04-08-10 --- CD4 = 720 / VL = 120
07-13-10 --- CD4 = 798 / VL = UD
10-13-10 --- CD4 = 570 / VL = UD
12-14-10 --- CD4 = 446 / VL = UD / % = 39
03-15-11 --- CD4 = 562 / VL = UD
06-28-11 --- CD4 = 580 / VL = UD
10-18-11 --- CD4 = NA /  VL = UD
02-21-12 --- CD4 = 865 / VL = UD / % = 41
07-03-12 --- CD4 = 507 / VL = UD / % = 36

Offline workingout

  • member
  • Posts: 1
Re: TMJ and Atripla
« Reply #10 on: March 09, 2010, 08:50:59 AM »
Very true for me as well. I'm at work and decided to search for why my jaw hurts. I've been Atripla since Nov 2009. Every morning I'm in soooo much pain. It goes away and gets a little easier. But I still can't chew properly or move my mouth they way I normally could. It was very alarming. But I have NO other side effects from taking the Atripla. And I love that. It's so damn easy to take. But these past few weeks (about 4 now) my jaw is in a lot of pain. Ughhhh. What to do?

Offline Gambit

  • Member
  • Posts: 24
Re: TMJ and Atripla
« Reply #11 on: March 14, 2010, 05:54:05 AM »
I talked to my Doctor about it and he said it sounds like TMJ (I swear I didn't say "TMJ" to him).  He said it does because I said the pain is the sharpest right where the hole of my ear is.  He told me to take aspirin.  That's it.  I didn't do it though..  Its gotten better for me though.  I'm not in much pain from it and it doesn't hurt to yawn or eat.  Its definitely still there though.. I can feel it every time I move my jaw, but at least the pain isn't terrible anymore.
01-07-10 --- CD4 = 347 / VL = 19,000 / % = 23
02-09-10 --- Started Atripla
02-25-10 --- CD4 = 478 / VL = 260
04-08-10 --- CD4 = 720 / VL = 120
07-13-10 --- CD4 = 798 / VL = UD
10-13-10 --- CD4 = 570 / VL = UD
12-14-10 --- CD4 = 446 / VL = UD / % = 39
03-15-11 --- CD4 = 562 / VL = UD
06-28-11 --- CD4 = 580 / VL = UD
10-18-11 --- CD4 = NA /  VL = UD
02-21-12 --- CD4 = 865 / VL = UD / % = 41
07-03-12 --- CD4 = 507 / VL = UD / % = 36

Offline J.R.E.

  • Member
  • Posts: 7,120
  • Joined Dec-2003 Living positive, since 1985.
Re: TMJ and Atripla
« Reply #12 on: March 14, 2010, 07:37:41 AM »
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 6/4/14,  t-cells are at 423, Viral load <40

 Current % is at 13% 

  
 62 years young.

Offline notoutinilm

  • Member
  • Posts: 33
Re: TMJ and Atripla
« Reply #13 on: March 15, 2010, 08:15:24 AM »
I switched from Atripla to another regiment a month or two ago.  Within 3 days of stopping Atripla my TMJ went back to its' normal self.  So in my book at least, Atripla does exacerbate TMJ.

 


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