Meds, Mind, Body & Benefits > Questions About Treatment & Side Effects

Quitting Lexiva

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slyder:
I have a question about stopping one of my meds.  I was diagnosed very early and immediately put on Sustiva, Truvada and Lexiva.  I am now down to undetectable and t-cells over 1000.  My Dr and I have talked about dropping the Lexiva now and she is comfortable with me doing that.  However as the day fast approaches for my last dose, I am getting really nervous.  I will be staying on Sustiva and Truvada, but my question is, can I develop resistance to the Lexiva now that I will be stopping it but staying on the other two?  She doesn't think so and I may be just over reacting a bit.  But I would appreciate some other people's advice.  Thanks!

newt:
Sustiva + Lexiva is extremely strong.  Normally you would use one or the other, not both.  The reason to use both at the beginning of treatment is to bomb the virus out asap.  It is a fair call to drop either Sustiva or Lexiva. If your infection was detected in its initial stages you could even think about a spell off treatment, which may turn out to be several years. A CD4 count of 1,000 is well normal (above 4-600 counts as normal).

- matt

slyder:
Thanks Newt!  That is what I was hoping to hear.  Yea we caught the thing during sero conversion and wanted to hit it hard.  The original plan has always been to drop the Lexiva once I was undetectable.  I was just getting concerned that if at some point I needed to go back on it, that I wouldn't have resistance issues.

newt:
Whichever drug you stop there should be no resistance issues.

- matt

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