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Author Topic: CD4  (Read 2248 times)

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Offline motherinneed

  • Member
  • Posts: 76
« on: September 04, 2008, 01:34:18 PM »
My son's CD4 count seems to never get above 500 but fluctuates in t he 400's and 300's
HIV sites say that one needs 500 to be less at risk for opportunistic infections. Why does the doctor say he is doing fine with this CD4 count? 

CD4 392
CD4 % 32
viral load less than 48 on

Offline Assurbanipal

  • Member
  • Posts: 2,175
  • Taking a forums break, still see PM's
Re: CD4
« Reply #1 on: September 04, 2008, 02:45:07 PM »
Hi motherinneed

When I look at my lab results they show both a result for me and a "reference interval" -- you can think of that reference interval as being sort of the normal range of results for someone who is not ill.  The reference interval for CD4 counts is 359-1519 for Labcorp (I think it may be different for Quest Diagnostics or other labs).  And the reference interval for CD4% is 30.8% to 58.5%.

Comparing those ranges to your son's results it looks like your son has an immune system that is comparable with healthy people who aren't Poz -- and the viral load remains undetectable too! 

You might want to look over the reference interval info on his labs to see how he compares against the values for his labs -- but it sounds like he is doing great!

5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%
2014 VL UD - 48
2015 VL 130 Moved to Triumeq

Offline newt

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  • Posts: 3,896
  • the one and original newt
Re: CD4
« Reply #2 on: September 04, 2008, 07:25:16 PM »
In short, what Mr A said

In truth., CD4 of 300+ is all that's needed, 400-500+ is "normal", viral load <50 when on treatment means that HIV is no longer causing damage/treatment is working.

Whatever website said 500+ CD4s is needed to prevent serious risk of opportunistic infections (OIs) is wrong, depends on the OI, and, generally, a CD4 below 300, or lower, is needed, for serious OIs to be a risk.

God bless

- matt
"The object is to be a well patient, not a good patient"

Offline aztecan

  • Member
  • Posts: 5,512
  • 31 years positive, 59 years a pain in the butt
Re: CD4
« Reply #3 on: September 08, 2008, 10:23:23 AM »
Hey Motherinneed,

Mr. A and Newt hit it on the head. People are very different and often don't mirror what the textbook says.

Another point to consider is each person probably starts with a different level of CD4s. Some may naturally have more than others. It doesn't mean one is deficient, just different.

So, I think what your son's doc is saying is correct. His percentage looks good, his numbers are fine and his meds are definitely working.

Hang in there Mom. Your son is a lucky guy.


"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline atlq

  • Member
  • Posts: 518
Re: CD4
« Reply #4 on: September 08, 2008, 10:44:39 AM »
My son's CD4 count seems to never get above 500 but fluctuates in t he 400's and 300's
HIV sites say that one needs 500 to be less at risk for opportunistic infections. Why does the doctor say he is doing fine with this CD4 count? 

CD4 392
CD4 % 32
viral load less than 48 on

Anecdotes don't replace science but...in my many years of counts, I have had a cd4 over 500 only once and have never had a cd4 percentage over 24 - and have never had an OI.....as Mark said, when we were neg, we all had widely varying cd4 counts...problem is we can never know what is "normal" for us because we only started counting after infection....Your doc is right, his numbers look very good....
“Keep up the good work....   And God bless you.”
  --  Sarah Palin, to members of the Alaskan Independence Party, 2008


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