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Author Topic: depression and Atripla  (Read 6999 times)

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Offline bretticus

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depression and Atripla
« on: August 25, 2008, 01:01:38 PM »
Has anyone heard of or experienced depression, presumably as a result of Atripla? I have been doing research on my own and find it had to understand why my doctor nor my psychiatrist has ever mentioned that Atripla can CAUSE or exaccerbate depression, all the while I have been struggling with jugging antidepressant, trying to find a combination which will work. I am thinking of switching hiv meds because of this. Whats up with that?
BretticusMaximus

Offline Miss Philicia

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Re: depression and Atripla
« Reply #1 on: August 25, 2008, 01:09:10 PM »
Yes, the Sustiva component of Atripla can cause/increase depression:

http://www.aidsmeds.com/archive/Sustiva_1615.shtml

... and yes, your doctor should have forewarned you.  Please call him and inform him of what is happening and for assistance in evaluating the level you are experiencing, etc.  Frankly I'd be suspect that he/she did not discuss this issue with you in advance.

Also, as you mention a psychiatrist I will assume that you began Atripla with pre-existing mental health issues.  Did your prescribing HIV specialist know of this, and was your prescribing psychiatrist conversely informed by you of what meds you were going on, etc.?  The patient must assist in informing each party of what's going on in a situation involving both an HIV specialist and a mental health professional.
« Last Edit: August 25, 2008, 01:11:23 PM by philly267 »
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Offline Ann

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Re: depression and Atripla
« Reply #2 on: August 25, 2008, 01:10:38 PM »
Hi Bret,

I've moved your thread into the Living forum, where you'll get more responses as that forum gets more traffic.

It's likely to be the Sustiva in the Atripla that is causing your depression. Definitely talk to your doc about switching.

Welcome to the forums!

Ann
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Offline bretticus

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Re: depression and Atripla
« Reply #3 on: August 25, 2008, 01:12:41 PM »
Do you have experience with this? i feel like an idiot not every hearing of this before...and struggling for so long with the depression issue. I feel like I am still alive today because I am an informed patient who has had a great relationship with his doctors....but not since leaving Baltimore...Damn I am pissed off about this
BretticusMaximus

Offline Iggy

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Re: depression and Atripla
« Reply #4 on: August 25, 2008, 01:20:24 PM »
How long have you been on Atripla?

As Philly already stated, Sustiva as a component of Atripla has been reported by many of those taken it (including my partner) to cause anxiety and depression type feelings.  In my partner's case, his doctor needed to prescribe an anti-anxiety med because he was having difficulty with the side effect.

Linked is the AIDSmeds lesson on Tips & Tricks on Taking Sustiva which you may want to check out as well.

http://www.aidsmeds.com/articles/SustivaTips_7550.shtml

Offline bretticus

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Re: depression and Atripla
« Reply #5 on: August 25, 2008, 01:34:26 PM »
Thank you...this is very helpful
BretticusMaximus

Offline madbrain

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Re: depression and Atripla
« Reply #6 on: August 25, 2008, 06:46:56 PM »
Has anyone heard of or experienced depression, presumably as a result of Atripla? I have been doing research on my own and find it had to understand why my doctor nor my psychiatrist has ever mentioned that Atripla can CAUSE or exaccerbate depression, all the while I have been struggling with jugging antidepressant, trying to find a combination which will work. I am thinking of switching hiv meds because of this. Whats up with that?

Do your psychiatrists and physician both have access to your full list of medications ?

If you are prone to depression and taking anti-depressant, you should not take Atripla. I am bipolar, but tend more towards depression. I am not on HIV meds yet, but I sometimes discuss the options with my HIV doctor. He has said that he would be very reluctant to put me on Atripla, due to this known issue with the sustiva component. I guess when my time comes for meds, I will take multiple pills for HIV.

Offline Desertguy

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Re: depression and Atripla
« Reply #7 on: August 25, 2008, 06:54:01 PM »
"Yes, the Sustiva component of Atripla can cause/increase depression:" Qoute from Philly

I agree with Philly, I have been on Atripla for 10 months.  & yes the depression set in about 2 months ago.  I have a Doc appointment 09/16 & will ask her about this, or maybe some anti-depressands even thou I hate them.

I also hate setting and eating at a restaurant and start crying for no reason.



Offline positively_me

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Re: depression and Atripla
« Reply #8 on: August 25, 2008, 07:50:05 PM »
Please talk to your doctor and your psychiatrist because Atripla and Sustiva definitely can exacerbate depression!  My ID doctor kept me away from Sustiva for years because I take antidepressants and she didn't want to make my depression worse.  When I ran out of meds to take due to side effects and Atripla had just been approved, I told her that I'd be willing to try it.  She only did so with the understanding that I would come back in 4 weeks to check in with her.  But it took almost 4 months for the depression to become completely unmanageable and to the point where I wanted to stop functioning.  I noticed, and someone else here on the forum posted about it, that within 2 hours of taking my Atripla at night...I had horrible thoughts of no self worth and not wanting to be here.  When my doctor took me off of them, I also had to change my antidepressants because she felt like those had maybe "pooped" out on me with the depression getting so bad.  Now I am on Isentress & Truvada for my hiv meds. They are working really well for me with hardly any side effects.

Your doctor and your psychiatrist should have none not to put you on them unless it was an absolute last resort and then only if they were going to closely monitor you.  Don't feel like an idiot for not hearing about this.  I was forewarned by my doctor and didn't think "it could happen to me".  Guess that's how I also ended up positive, huh???   ;)   

You're welcome to PM me if you want to ask any specific questions about my experience.  Good luck to you and I hope you feel better soon!
Great minds discuss ideas; Average minds discuss events; Small minds discuss people.  - Eleanor Roosevelt

Offline lucas clay

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Re: depression and Atripla
« Reply #9 on: August 26, 2008, 04:07:21 AM »
It will do a number on you.

                                    Lucas

Offline bretticus

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Re: depression and Atripla
« Reply #10 on: August 29, 2008, 01:48:40 PM »
thank you
BretticusMaximus

Offline red_Dragon888

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Re: depression and Atripla
« Reply #11 on: August 29, 2008, 10:11:15 PM »
Hi Bret,

I've moved your thread into the Living forum, where you'll get more responses as that forum gets more traffic.

It's likely to be the Sustiva in the Atripla that is causing your depression. Definitely talk to your doc about switching.

Welcome to the forums!

Ann


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Offline madbrain

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Re: depression and Atripla
« Reply #12 on: August 30, 2008, 03:53:38 AM »
I wonder if you switch can you switch back?

As long as you haven't developed resistance to the Sustiva, you can probably switch back. Ask your doc. However, if you have depression caused by the Sustiva, you might just not want to switch back unless it's the only med to which you are not resistant.

Offline Desertguy

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Re: depression and Atripla
« Reply #13 on: September 03, 2008, 09:49:20 AM »
I switched from Atripla to Truvada & Kalitra 10 days ago & notice a difference already.  but the sides effects are taking time to get over.

Offline David_CA

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Re: depression and Atripla
« Reply #14 on: September 03, 2008, 10:24:40 AM »
Hubby and I both take Sustiva in Atripla form.  Neither of us notice any depression in over 18 months of being on it.  It seems to be an individual thing.  Most folks seem ok on it, but the ones that have depression problems seem to have 'em bad.

David
Black Friday 03-03-2006
03-23-06 CD4 359 @27.4% VL 75,938
06-01-06 CD4 462 @24.3% VL > 100,000
08-15-06 CD4 388 @22.8% VL >  "
10-21-06 CD4 285 @21.9% VL >  "
  Atripla started 12-01-2006
01-08-07 CD4 429 @26.8% VL 1872!
05-08-07 CD4 478 @28.1% VL 740
08-03-07 CD4 509 @31.8% VL 370
11-06-07 CD4 570 @30.0% VL 140
02-21-08 CD4 648 @32.4% VL 600
05-19-08 CD4 695 @33.1% VL < 48 undetectable!
08-21-08 CD4 725 @34.5%
11-11-08 CD4 672 @39.5%
02-11-09 CD4 773 @36.8%
05-11-09 CD4 615 @36.2%
08-19-09 CD4 770 @38.5%
11-19-09 CD4 944 @33.7%
02-17-10 CD4 678 @39.9%  
06-03-10 CD4 768 @34.9%
09-21-10 CD4 685 @40.3%
01-10-11 CD4 908 @36.3%
05-23-11 CD4 846 @36.8% VL 80
02-13-12 CD4 911 @41.4% VL<20
You must be the change you want to see in the world.  Mahatma Gandhi

Offline Desertguy

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Re: depression and Atripla
« Reply #15 on: September 03, 2008, 02:14:37 PM »
David your saying I'm depressed??????

Just kidding!!  LoL ::)

Offline David_CA

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Re: depression and Atripla
« Reply #16 on: September 03, 2008, 09:30:57 PM »
David your saying I'm depressed??????

Just kidding!!  LoL ::)

I should have said that Atripla / Sustiva seem to cause big problems with depression in some individuals.   ;)
Black Friday 03-03-2006
03-23-06 CD4 359 @27.4% VL 75,938
06-01-06 CD4 462 @24.3% VL > 100,000
08-15-06 CD4 388 @22.8% VL >  "
10-21-06 CD4 285 @21.9% VL >  "
  Atripla started 12-01-2006
01-08-07 CD4 429 @26.8% VL 1872!
05-08-07 CD4 478 @28.1% VL 740
08-03-07 CD4 509 @31.8% VL 370
11-06-07 CD4 570 @30.0% VL 140
02-21-08 CD4 648 @32.4% VL 600
05-19-08 CD4 695 @33.1% VL < 48 undetectable!
08-21-08 CD4 725 @34.5%
11-11-08 CD4 672 @39.5%
02-11-09 CD4 773 @36.8%
05-11-09 CD4 615 @36.2%
08-19-09 CD4 770 @38.5%
11-19-09 CD4 944 @33.7%
02-17-10 CD4 678 @39.9%  
06-03-10 CD4 768 @34.9%
09-21-10 CD4 685 @40.3%
01-10-11 CD4 908 @36.3%
05-23-11 CD4 846 @36.8% VL 80
02-13-12 CD4 911 @41.4% VL<20
You must be the change you want to see in the world.  Mahatma Gandhi

 


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