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Author Topic: Advice on new med regimen requested  (Read 1442 times)

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Offline Iggy

  • Member
  • Posts: 2,435
Advice on new med regimen requested
« on: August 19, 2008, 06:35:34 PM »
Ok folks, starting the next phase of the clinical trials for the Viramune study.

Up till now, (last 3 weeks) I have been having to take only the one viramune (half dosage) at night along with a Truvada.  Starting tomorrow morning I begin my twice a day treatment which is one Truvada a day and then three "Viramune" pills (either two in the morning and one in the evening or visa versa) a day.

The thing about the "Viramune" is that one of the two bottles contains a placebo (I have to take a mix of the two bottles everyday).

So here's the question:  Does anyone think it matters or has any advice as to taking either the two Viramune in the morning or evening and whether it is better to take truvada in mornings or evenings.

Not particularly worried or concerned to be honest, just thought I ask the group in general in case anyone has a specific leaning.


Offline J.R.E.

  • Member
  • Posts: 7,162
  • Joined Dec-2003 Living positive, since 1985.
Re: Advice on new med regimen requested
« Reply #1 on: August 19, 2008, 06:55:21 PM »
Hey Iggy,

I would continue taking the Truvada at night, As you have been. I would probably take the two viramunes in the evening, since you will be going to bed. Take one in the day

When I was taking both my viramunes ( at the same time) I was taking them in the morning, along with the Epzicom( which is a combination of two drugs). Then I would take the Viread by itself at night.

Just my thoughts.---Ray
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 8/2514,  t-cells are at 402, Viral load <40

 Current % is at 11%

  
 62 years young.

Offline AlanBama

  • Member
  • Posts: 3,626
  • Alabama: the 'other' 3rd World Country!
Re: Advice on new med regimen requested
« Reply #2 on: August 19, 2008, 08:21:18 PM »
Ig,

I take one Viramune mid-day; the other at bedtime with the Truvada.   I could take them all at the same time, but have done twice-a-day dosing for so many years, it is second nature to me. 

My complaint with Truvada is the G.I. issues (gas/bloat/discomfort)....I take it at night to try to 'lessen' the effects (but not sure how much good that does!)
"Remember my sentimental friend that a heart is not judged by how much you love, but by how much you are loved by others." - The Wizard of Oz

Offline David_CA

  • Member
  • Posts: 3,246
  • Joined: March 2006
Re: Advice on new med regimen requested
« Reply #3 on: August 19, 2008, 09:39:49 PM »
I take my Truvada (in the form of Atripla) in the morning.  I haven't noticed any effects from it at all, and it seems to be working!

David
Black Friday 03-03-2006
03-23-06 CD4 359 @27.4% VL 75,938
06-01-06 CD4 462 @24.3% VL > 100,000
08-15-06 CD4 388 @22.8% VL >  "
10-21-06 CD4 285 @21.9% VL >  "
  Atripla started 12-01-2006
01-08-07 CD4 429 @26.8% VL 1872!
05-08-07 CD4 478 @28.1% VL 740
08-03-07 CD4 509 @31.8% VL 370
11-06-07 CD4 570 @30.0% VL 140
02-21-08 CD4 648 @32.4% VL 600
05-19-08 CD4 695 @33.1% VL < 48 undetectable!
08-21-08 CD4 725 @34.5%
11-11-08 CD4 672 @39.5%
02-11-09 CD4 773 @36.8%
05-11-09 CD4 615 @36.2%
08-19-09 CD4 770 @38.5%
11-19-09 CD4 944 @33.7%
02-17-10 CD4 678 @39.9%  
06-03-10 CD4 768 @34.9%
09-21-10 CD4 685 @40.3%
01-10-11 CD4 908 @36.3%
05-23-11 CD4 846 @36.8% VL 80
02-13-12 CD4 911 @41.4% VL<20
You must be the change you want to see in the world.  Mahatma Gandhi

Offline fearless

  • Member
  • Posts: 2,191
Re: Advice on new med regimen requested
« Reply #4 on: August 19, 2008, 11:29:46 PM »
hey Iggy,

no advice. i take my truvada in the morning but simply because i'm more consistent at that time of day and therefore less likely to forget.

off topic a bit, but what are they trying to study in your trial? your regimen of mixing a placebo and viramune has me interested. ok to point me to another thread if i missed it.
Be forgiving, be grateful, be optimistic

Offline Robert

  • Member
  • Posts: 2,644
Re: Advice on new med regimen requested
« Reply #5 on: August 20, 2008, 12:43:34 AM »
Hi iggy.

I'm a morning man myself.  They say Sustiva causes nightmares but I have my share of them every night.  I can't imagine what it would be like to take my Truvada at night.

..........

Offline Iggy

  • Member
  • Posts: 2,435
Re: Advice on new med regimen requested
« Reply #6 on: August 20, 2008, 07:32:36 AM »
I really appreciate everyone's advice and thoughts. 

I've decided to stay with the Truvada in the evening along with the one Viramune, as I was already taking those two at night anyway so it will be easier to transition to a new schedule, and also based  on Alan's reminder about bloated/gas (this way only Jeromy has to suffer any night bursts if they happen  :D )

So my schedule will be:

Morning
- 2 Viramune (1 Blue label bottle & 1 Yellow label bottle)

Evening
- 1 Viramune (Blue label bottle)
- 1 Truvada

Add my Valtrex and Testim, and my side of the medicine tray is comparable to Jeromy's!  Actually he has this great daily med dispenser which has compartments for morning and evening dosages which I'm going to use and set up my meds every week in advance so I don't forget.

off topic a bit, but what are they trying to study in your trial? your regimen of mixing a placebo and viramune has me interested. ok to point me to another thread if i missed it.

Hey Steve,

The purpose of the study is basically just to study extended release Viramune and hence why the placebo is in the mix.  Most likely the blue labeled bottles (which I take twice a day) are the placebos and the yellow labeled is the extended, or I don't have the extended at all and the yellow is the placebo with the blue being the regular viramune.


 


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