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Author Topic: Reason for Huge Tcell drop?  (Read 2229 times)

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Offline richie

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  • Posts: 69
Reason for Huge Tcell drop?
« on: August 01, 2008, 02:39:45 PM »
Looking for similar experience, if any.

Been extremely healthy for years, tcells slowly climbing into the 600s, on Truvada, Lexiva (w/Norvir).  50 yrs old, no complaints, undetectable for a long long time.  Last checkup, my tcells dropped 50% to 300.  No reason.  Still undetectable.  Everything else cool -- no infections (that we're aware of). 

Anyone experience this before?  Perhaps a lab screwup?  Too much stress?  What types of things are most likely (common) to cause tcells to drop?  Do I have a huge brain tumor now from too much cell phone use?  Told my doctor to retest to be 100% sure, but I've never had an inaccurate test (that I'm aware of).

Thanks for any info and experience you can provide!

Offline NewLife4Me

  • Member
  • Posts: 24
Re: Reason for Huge Tcell drop?
« Reply #1 on: August 01, 2008, 02:46:01 PM »
That really is a drop. Lets hope for lab screw up!

I have a question for you though. How long have you been on your current regimen and when you started did you have horrible side effect? I started the same combo 5 weeks ago and if the nausea and numbness in my lip does not end soon I am going to have a break down and she aint gonna be so pretty.


Offline newt

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  • Posts: 3,896
  • the one and original newt
Re: Reason for Huge Tcell drop?
« Reply #2 on: August 01, 2008, 03:28:16 PM »
So what? sez the newt, 300 is enough, and maybe they were hiding deep in your body when the test was drawn, sample sat on a sunny shelf, you slept bad, different time of day, bad machine calibration etc etc. 1 odd test does not a trend make +/-50 is the margin of error for a CD4 test under perfect circumstances, +/- 100-150 is a well possible difference between two tests. 600 could be 450 and 300 could be 450 easy peasy.  It's the trend that counts.

I sincerely hope this is a one-off though.

- matt
"The object is to be a well patient, not a good patient"

Offline richie

  • Member
  • Posts: 69
Re: Reason for Huge Tcell drop?
« Reply #3 on: August 01, 2008, 04:39:55 PM »
NewLife4me:  Been on this regimen for a few yrs.  It's great, except for the Norvir (yuck).  I had a fabulous rash when I first started (from the Lexiva) that went away with usual treatment (antihistamines, etc.).  But then, I always get a rash with pretty much all new drugs.  Stick with it for 60 - 90 days and see if all levels out for you.

Newt:  thanks, that's my original reaction, but then after thinking about it, it's really out of whack for me.  Really solid trendline for a long time (upwards) and recently took steps to reduce stress and do things I really like (so I was trying to really increase, not decrease!)  I was thinking my lifestyle change would boost me upwards.  Came as a real shocker from the blue.   Hopefully I won't die tomorrow ;-)   Yes, that's sarcasm for anyone out there reading this!  More likely I'll get hit by a bus.

Offline weasel

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  • Posts: 1,866
Re: Reason for Huge Tcell drop?
« Reply #4 on: August 10, 2008, 07:58:13 AM »
Hey Richie  :),
                     I had the same thing happen to me several months ago  :o

                    the next test was back to normal  under 50 and    t cells back to where they were !

                      My V.A. Doctor  insists that it was a LAB SCREW-UP  , and refuses to blieve other wise  :)

                    I was scared  :o , but docor was sure it was not my system ,but theirs  ::)

                   things have been fine ever since that mix-up !

                                                good luck & do not worry too much  :)

" Live and let Live "


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