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Author Topic: Statments on HIV tests  (Read 2033 times)

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Offline ubotts

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  • Posts: 347
Statments on HIV tests
« on: June 23, 2008, 07:28:18 AM »
http://www.nypost.com/seven/06222008/news/regionalnews/hiv_false_positive_test_stress_116691.htm


The New York Post
Sunday, June 22, 2008

HIV 'FALSE POSITIVE' TEST STRESS

By MELISSA KLEIN

June 22, 2008 -- Hundreds of people were incorrectly told they had tested positive for HIV at New York City STD clinics this winter.

Almost half the results given by the clinics were false positives, the Department of Health confirmed.

From November to April, 213 people tested positive after taking a rapid mouth-swab HIV test. A second test revealed they did not have the virus.

The city would not explain why, as false positives mounted, it continued to administer the tests.

The reason for the spike is under investigation by the DOH, the federal Centers for Disease Control and Prevention and test manufacturer OraSure Technologies. The DOH said it had stopped using OraSure's rapid swab tests.


DOH said anyone who received a positive result from the oral test was immediately given another test, this time using a finger stick to take blood.

"Nobody was misled or harmed," said Dr. Susan Blank, assistant DOH commissioner and director of the bureau of STD control.


The swab tests proved popular after they were introduced at city STD clinics in 2005. The number of people tested for HIV grew 24 percent that year.


Additional reporting by Susan Edelman

Melissa.klein@nypost.com

-------------------------------------------------

http://www.wnbc.com/news/16678557/detail.html


NYC Health Dept. Statement On HIV Tests


Oral testing increases the number of people who can get tested for HIV.

Overall, less than a third of one percent - 0.3 percent - of the more than 130,000 oral tests performed at the Health Department's STD clinics have yielded false positives. The FDA's standard for HIV screening tests allows false positive rates of up to 2 percent.

Between October 2007 and April 2008, the Health Department documented a higher-than-usual percentage of false positive oral HIV tests in STD clinics, with the false-positive rate reaching 1.1 percent in some months. This rate is below the FDA threshold of 2 percent but higher than expected. A similar phenomenon was observed in December of 2005 but resolved within a few months.

Data for the month of May 2008 showed that the oral test's specificity (the accuracy of positive results) had returned to the usual level of 99.9 percent for the nearly 5,000 oral tests administered that month.

Some false positives are inevitable with any test, so any positive screening test must be confirmed with a second, more definitive test. In addition to a confirmatory lab test, which typically takes three to five days, anyone who receives a preliminary positive oral HIV test is also offered a rapid blood test before leaving the clinic to identify likely false positives, as rapid blood tests are slightly more accurate than those using oral fluid.

If a rapid oral test is positive and the rapid blood test is negative, patients are told that the negative result is far more likely to be valid. All patients with positive rapid HIV tests are offered referral to HIV primary care.

Since October, 2007 an unusually large number of people have required two tests. The Department's STD clinics switched to rapid blood tests while investigating the problem. The reason for slight increase in false positive tests is not clear, but the Health Department is working with CDC and the manufacturer to identify the cause. So far, false positive tests have not been linked to test kit handling, storage conditions, lot numbers, clinic sites or test operators.

HIV testing in New York City remains safe, convenient, and highly accurate - and false positives are rare. The Health Department provided close to 60,000 HIV rapid oral tests in 2007 - twice the number given in 2003. Even with recent fluctuations in test performance at some Health Department STD clinic sites, the accuracy of rapid oral tests has remained well above 98% citywide.

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