Using tenfovir (Viread) with abacavir (Ziagen)

Meds, Mind, Body & Benefits > Questions About Treatment & Side Effects

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J.R.E.:
Hello Herman,

I was always on Viramune, epivir, ziagen, since the beginning. Actually Zerit was used a month or so, prior to switching to Ziagen. When Epzicom, became available, I switched to that, to make dosing easier. it was basically the first regimen I was started on, back in October of 2003.

Viread was added to the mix, it was either August or September 1st, Of 04.Was having trouble getting to <50 viral load. But have succeeded, at keeping <50 since the Viread was added. (except for one blip of 166) I am still waiting on a viral load, should be in sometime this week. So, we'll see what happens.

I had some muscle ache and weakness, after the Viread was added. This lasted less then 4 weeks. The main side effect I deal with is PN. And that occurred, well before Viread was introduced. Also dealing with larger then normal gut area ! But, otherwise, things are not that bad. Day by day...

The Best-----Ray

frenchpat:
Hi,

as this is now on page two I am hoping someone will still read it and be able to give me some advice.

As I am staring lipo in the eyes right now and it is not too bad yet, I've asked my doctor what the options were if I switched from my current epivir + zerit duo. He suggests Ziagen + Kaletra + Viread.

I am very new to all the jargon and have a hard time understanding all Newt writes here. So please give me the lowdown on this combination and I promess I will try to learn "Newtspeak" soon.

Pat

newt:
Okay simple version I hope...

Suggested combo for first-time therapy is made up of:

2 nukes PLUS EITHER 1 non-nuke OR 1 boosted protease inhibitor .
(Deux 'nukes' avec un 'non-nuke' ou un inhibiteur de protéase amplifié)

Recommended pairs of nukes:

3TC+AZT (comes in 1 tablet called Combivir)
Viread+FTC (comes in 1 tablet called Truvada)
Ziagen+3TC (comes in 1 tablet called Kivexa in Europe)

Non-nukes:

Sustiva
Viramune

Some boosted protease inhibitors (Norvir is the booster):

Kaltetra (includes Norvir)
Invirase (+ Norvir)
Reyataz (+ Norvir)
Lexiva (+Norvir)

The combination suggested by your doc is not standard. Ziagen + Viread is not a recommended first-line nuke pair. But even though it's not standard, you will probably get a good response on Kaletra + Viread + Ziagen.

Voulez-vous des renseignements spécialisés sur les traitements en francais? Allez ici!

- matt

Cliff:

--- Quote from: frenchpat on July 10, 2006, 02:18:27 PM ---As I am staring lipo in the eyes right now and it is not too bad yet, I've asked my doctor what the options were if I switched from my current epivir + zerit duo. He suggests Ziagen + Kaletra + Viread.
--- End quote ---
Does the doctor suspect both 3TC and Zerit to be involved in the lipo or is he just going for a clean break? I'm just wondering why he didn't continue the 3TC (or FTC via Truvada), and simply dropped the Zerit.

I always thought 3TC/FTC weren't suspects in lipo.

frenchpat:
Ok,

so if I am not too thick, the combivir is equivalent to my present treatment of zerit + epivir right? ???
I am not sure why my doc would not keep the epivir and just drop the zerit and it is a question I will ask him.

And Newt, thank you for the explanation and the french link. I just hate accronyms and I have a technical job just full of them...
Could you tell me why it is that Ziagen + Viread is not recommended?

thanks a lot guys for the quick answers

Pat

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