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Author Topic: Norvir Storage  (Read 2269 times)

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Offline Londonguy

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Norvir Storage
« on: May 28, 2008, 11:58:28 AM »
On the side of the norvir container it says that they can be kept for up to 30 days at room temperature.  Say they're kept at room temperature for a week, and then put in the fridge, will they be ok from then on, or will they still have to be used within 30 days because of the amount of time they've been at room temperature?

Offline Miss Philicia

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Re: Norvir Storage
« Reply #1 on: May 28, 2008, 12:37:26 PM »
I would think it would still be fine, but frankly if you're that worried your better off asking a licensed pharmacist this question.
"Iíve slept with enough men to know that Iím not gay"

Offline antibody

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Re: Norvir Storage
« Reply #2 on: May 28, 2008, 02:02:02 PM »
they say that they ok at room temp for 30 days.
Timbuk      <50/ 794  CD4 10/06 
                 <50/ 1096 CD4 3/07
                 <40/ 1854 CD4 4/09

Started Atripla  7/14/06
Switched to boosted Reyataz Truvada 3/28/07

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Offline shadowfluid

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Re: Norvir Storage
« Reply #3 on: May 28, 2008, 02:55:05 PM »
On the side of the norvir container it says that they can be kept for up to 30 days at room temperature.  Say they're kept at room temperature for a week, and then put in the fridge, will they be ok from then on, or will they still have to be used within 30 days because of the amount of time they've been at room temperature?
I know I only throw them in the fridge on super hot days as my apt has no A/C and can get up to 80 degrees
Jan 08       321/23%  VL 92,000 (very mild shingles)
Feb 1 08    Start Truvada+Viramune
March 08    470/33%  VL 320
mid-May     Start Reyataz/Norvir/Truvada
June 08      571/ 40%     VL   80
August 08   585/ 33%     VL >50
Nov  Lab error!!!!!!!!wah.
Jan 09        535      Undetectable
March 11     756

Offline Miss Philicia

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Re: Norvir Storage
« Reply #4 on: May 28, 2008, 03:19:04 PM »
Correct me if I'm wrong, but I think London's question is specifically about bringing the med to room temperature and then putting it back in the refrigerator, no?  It's obvious from his first post that he realizes it's OK at room temperature for 30 days.

His question is more along the lines of refreezing thawed meat.

Anyway, I've done what he's asking and nothing untoward occurred.
"Iíve slept with enough men to know that Iím not gay"

Offline Londonguy

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Re: Norvir Storage
« Reply #5 on: May 28, 2008, 04:35:08 PM »
Yeah you're right Philly.  Something family related has come up and I may be away from home for a while.  The family I'll be staying with don't know of my status and now is really not the best time to bring it up.  I just wasn't sure if, by leaving it unrefrigerated for so long, it would start some kind of chemical reaction that would mean it would have to be used within 30 days, even if it was put back in the fridge within the 30 day period.

I imagine it will be ok but I wasn't too sure and I can't find anything on the net one way or another really.  Which hopefully means it isn't an issue.

Offline Assurbanipal

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Re: Norvir Storage
« Reply #6 on: May 28, 2008, 07:56:14 PM »
If it's just a limited period visit, could you perhaps just count out what you need plus a few extra and leave the rest at home in the refrigerator?
5/06 VL 1M+, CD4 22, 5% , pneumonia, thrush -- O2 support 2 months, 6/06 +Kaletra/Truvada
9/06 VL 3959 CD4 297 13.5% 12/06 VL <400 CD4 350 15.2% +Pravachol
2007 VL<400, 70, 50 CD4 408-729 16.0% -19.7%
2008 VL UD CD4 468 - 538 16.7% - 24.6% Osteoporosis 11/08 doubled Pravachol, +Calcium/D
02/09 VL 100 CD4 616 23.7% 03/09 VL 130 5/09 VL 100 CD4 540 28.4% +Actonel (osteoporosis) 7/09 VL 130
8/09  new regimen Isentress/Epzicom 9/09 VL UD CD4 621 32.7% 11/09 VL UD CD4 607 26.4% swap Isentress for Prezista/Norvir 12/09 (liver and muscle issues) VL 50
2010 VL UD CD4 573-680 26.1% - 30.9% 12/10 VL 20
2011 VL UD-20 CD4 568-673 24.7%-30.6%
2012 VL UD swap Prezista/Norvir for Reyataz drop statin CD4 768-828 26.7%-30.7%

Offline MSPspud

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Re: Norvir Storage
« Reply #7 on: May 28, 2008, 09:35:06 PM »
I've done the trick of taking my 3 month supply of meds out of the fridge for a week and then resuming with no issues.  Granted, I haven't asked a professional but they have continued to work for me. 

Offline Peter Staley

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Re: Norvir Storage
« Reply #8 on: May 29, 2008, 05:47:46 PM »
My understanding of why Norvir needs to be protected from heat or long-term room temperature is because the capsule formulation contains castor oil, which like many cooking oils, spoils over time.

The 30 day recommendation is probably conservative.  I use olive oil that's been at room temperature for much longer than that.  Then again, cooking oils do go rancid over time.

But to your exact question, I would think putting it back in the frig doesn't restart the clock.  The oil is always aging, and it ages much slower in colder temps.  Cooling it won't reverse any of the previous aging.

Does this make sense?

Peter

Offline Londonguy

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Re: Norvir Storage
« Reply #9 on: May 29, 2008, 08:10:47 PM »
Yeah I understand it won't reverse.  What im basically asking is...say there are 70 capsules in the container and they're unrefrigerated for a week or two.  When they go back in the fridge, are the remaining capsules all going to be ok or will they only be good for a few more weeks?
« Last Edit: May 29, 2008, 08:15:06 PM by Londonguy »

Offline Peter Staley

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Re: Norvir Storage
« Reply #10 on: May 30, 2008, 11:12:04 AM »
Putting them back in the frig would be like almost stopping their decay clock, so they should be fine (again, like all meds, they will continue to decay slowly over time, even in the frig -- thus the expiration date on the bottle).

 


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