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Author Topic: Over-the-Counter Hydroxycloroquine as an HIV suppressant  (Read 4955 times)

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Offline pozbottom

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Over-the-Counter Hydroxycloroquine as an HIV suppressant
« on: July 03, 2007, 04:36:32 PM »
Hi Everyone,

Today, I discovered this form of quinine that, by medical studies, shows results as a possible HIV therapy.  Here's one of many reports:

http://www3.interscience.wiley.com/cgi-bin/abstract/112212475/ABSTRACT?CRETRY=1&SRETRY=0

Comments?  Just curious, have any of you had experience with this?

I went to a local pharmacy today and they told me its now a prescription drug, no longer over the counter, wouldn't you know...   Curious if its OTC in other states?  I'm in california.

...Doug
03/22/07 tested positive.

Offline pozbottom

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #1 on: July 03, 2007, 04:38:53 PM »
Hmm..  Seems the link doesn't work as posted on the forum.   Here's my Google search, and the link (today) third from the top.

http://www.google.com/search?hl=en&q=hcq+hiv+over+the+counter
.
.
.
[PDF] The antiinflammatory and antiviral effects of hydroxychloroquine ...File Format: PDF/Adobe Acrobat
ability of HCQ to inhibit the replication of HIV (as. well as other viruses) in vitro and in vivo ... multiple reasons for choosing HCQ over other agents.

doi.wiley.com/10.1002/art.1780390122

03/22/07 tested positive.

Offline pozbottom

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03/22/07 tested positive.

Offline Cerrid

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #3 on: July 03, 2007, 04:53:04 PM »
Well, the chloroquin works against malaria, the protease inhibitor works against HIV. No surprise then that a mixture of both drugs works against both diseases. What's new about this? Or did I miss the point?
"Boredom is always counterrevolutionary. Always." (Guy Debord)

Offline milker

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #4 on: July 03, 2007, 05:30:52 PM »
Problem is that the in vivo tests have been done back in 1993 and 1995. The recent studies reference those from 1993  , so we need more real studies done to see the real effect. But it's interesting!

Milker.
mid-dec: stupid ass
mid-jan: seroconversion
mid-feb: poz
mar 07: cd4 432 (35%) vl 54000
may 07: cd4 399 (28%) vl 27760
jul 07: cd4 403 (26%) vl 99241
oct 07: cd4 353 (24%) vl 29993
jan 08: cd4 332 (26%) vl 33308
mar 08: cd4 392 (23%) vl 75548
jun 08: cd4 325 (27%) vl 45880
oct 08: cd4 197 (20%) vl 154000 <== aids diagnosis
nov 2 08 start Atripla
nov 30 08: cd4 478 (23%) vl 1880 !!!!!!!!!!!!!!!!!!!!!!!!!!
feb 19 09: cd4 398 (24%) vl 430 getting there!
apr 23 09: cd4 604 (29%) vl 50 woohoo :D :D
jul 30 09: cd4 512 (29%) vl undetectable :D :D
may 27 10: cd4 655 (32%) vl undetectable :D :D

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Offline pozbottom

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #5 on: July 04, 2007, 11:10:56 AM »
Cerrid,

The point is, HCQ works as an HIV inhibitor, and costs $60 a month, vs $2000+ for the cocktails. 

I'm not on meds right now, and something like this could be a good cheap way to push out the inevitable.

Milker, keep writing!  I enjoy reading your posts. (Still remembering "hiv everything... Nothing on tv, its the HIV...")

...Doug
03/22/07 tested positive.

Offline pozbottom

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #6 on: July 05, 2007, 11:27:22 AM »
Hmm...

Here is a patent filed for the use of cloroquine and derivatives for use as an HIV inhibitor.

http://www.patentstorm.us/patents/5668149-description.html

Its also dated in the late 90s.  I'd love to find more recent information.

...Doug
03/22/07 tested positive.

Offline sloth

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #7 on: July 06, 2007, 01:42:01 AM »
An in vitro study, which was published this year, can be found at:
http://www.retrovirology.com/content/4/1/6

I'll be honest, the technical stuff made my head swim!  But the literature review is interesting, and its references have links to studies done during the past 10 years. And... if I am interpreting this sentence correctly, I think a clinical trial is planned:
Quote
The significance of these findings to the in vivo setting will be identified through the study of HIV-1 infected individuals treated with CQ.

It sounds encouraging!  :)

Offline pozbottom

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #8 on: July 06, 2007, 03:21:42 AM »
From a link from the National Library of Medicine, a report from the Department of Clinical Immunology, Mount Sinai School of Medicine, New York, with solid evidence,  "suggesting"  HCQ and CQ for use as an HIV inhibitor, in conjunction with other meds.

http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=11166661&dopt=Abstract

Okay, I'm wonder if they didn't have the ball to make this a recommendation, or on the postive side, are trying to raise recognition of HCQ and CQ to the public, and also by saying "in conjunction with", hope that the drug industry adopts it.

...things that make me go, "hmmm..."
03/22/07 tested positive.

Offline pozbottom

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #9 on: July 06, 2007, 04:08:49 AM »
wow, here's how it works down to the protein, amino acid level.  My head is spinning!!!

http://www.retrovirology.com/content/4/1/6

Oh, another interesting site, a glossary of drugs, suppliments, etc., for poz people.

http://www.aidsmap.com/cms1032143.asp

um, I'm just posting this stuff for discussion.

Question:  Have any of you discussed HQC with your doctor?  I'd love to know what he says.

...Doug


03/22/07 tested positive.

Offline Central79

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #10 on: May 02, 2008, 06:54:44 AM »
I came across this thread searching for hydroxychloroquine on the forums. I've just been offered a place in a study for treatment naive patients with CD4s greater than 500. The research nurse is going to ring me with more details, but I'm doing some legwork in the meantime.

Matt.
Diagnosed January 2006
26/1/06 - 860 (22%), VL > 500,000
24/4/06 - 820 (24.6%), VL 158,000
13/7/06 - 840 (22%), VL 268,000
1/11/06 - 680 (21%), VL 93,100
29/1/07 - 1,020 (27.5%), VL 46,500
15/5/07 - 1,140 (22.8%), VL not done.
13/10/07 - 759 (23.2%), VL 170,000
6/11/07 - 630 (25%), VL 19,324
14/1/08 - 650 (21%), VL 16,192
15/4/08 - 590 (21%), VL 40, 832

Offline newt

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #11 on: May 02, 2008, 08:06:49 AM »
This is the trial.

Evaluation of the efficacy of hydroxychloroquine in decreasing immune activation and viral replication in asymptomatic Human Immunodeficiency Virus (HIV)-infected patients

http://www.controlled-trials.com/mrct/trial/337129/hydroxychloroquine+

It's a rather interesting study. I see as yet there is no patient information material listed on the database entry though...

- matt
"The object is to be a well patient, not a good patient"

Offline bimazek

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #12 on: May 03, 2008, 02:30:44 AM »
sounds great
honestly i have been drinking
Tonic water as often as possible since i became poz hoping it would slow hiv down a bit
they even have
diet Tonic water
--- i have a fantasy, no proof no proof at all that the diet chemicals will slow hiv down
i know it is not true
i have not even looked into it at all
but before i worried about the sweet and low giving me cancer

now i just tell myself that the sweet and low inhibits my hiv

lol

Offline Dachshund

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #13 on: May 03, 2008, 08:56:00 AM »
sounds great
honestly i have been drinking
Tonic water as often as possible since i became poz hoping it would slow hiv down a bit
they even have
diet Tonic water
--- i have a fantasy, no proof no proof at all that the diet chemicals will slow hiv down
i know it is not true
i have not even looked into it at all
but before i worried about the sweet and low giving me cancer

now i just tell myself that the sweet and low inhibits my hiv

lol


Of course you do know they're not talking about Tonic Water don't you? You are right about one thing, you do have a fantasy. I imagine drinking too much Tonic Water is probably not good for your health, especially diet.

Tonic water is a carbonated beverage that derives its somewhat bitter taste from the addition of quinine. It is usually flavored with lemon or lime, lots of sugar, and often contains caffeine.

Offline shadowfluid

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  • Mike
Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #14 on: May 08, 2008, 12:49:22 AM »
sounds great
honestly i have been drinking
Tonic water as often as possible since i became poz hoping it would slow hiv down a bit
they even have
diet Tonic water
--- i have a fantasy, no proof no proof at all that the diet chemicals will slow hiv down
i know it is not true
i have not even looked into it at all
but before i worried about the sweet and low giving me cancer

now i just tell myself that the sweet and low inhibits my hiv

lol


Best. Reply. Ever.
Jan 08       321/23%  VL 92,000 (very mild shingles)
Feb 1 08    Start Truvada+Viramune
March 08    470/33%  VL 320
mid-May     Start Reyataz/Norvir/Truvada
June 08      571/ 40%     VL   80
August 08   585/ 33%     VL >50
Nov  Lab error!!!!!!!!wah.
Jan 09        535      Undetectable
March 11     756

Offline ubotts

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #15 on: May 08, 2008, 05:10:32 AM »
I first put on tonic water and couldnt stand the bitter taste, so when I went back to my dr..She put me on tonic pills that was suppose to take away my leg cramps at night and the charlie horses in my legs feet and toes..

It did work great for me..But then all of a sudden they took me off it right away, and didnt say why...They said something to the effect its now good if you have hep C..
Go figure..
Live Love Laugh and dance like no ones watching.
Laughter is the best medicine, so try to have a laugh everyday..Even if your not feeling your best, think about something that was funny at one time in your life and work with it..   :o)

Offline Jacques

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Re: Over-the-Counter Hydroxycloroquine as an HIV suppressant
« Reply #16 on: May 08, 2008, 11:48:13 PM »
Quote
I first put on tonic water and couldnt stand the bitter taste


To cut  the bitter  taste of tonic  water , I dilute it  with gin.  :P

cheers 

Jacques
Jacques
Living positively since 1987
latest lab :july 2010
Undetectable Cd4 1080
43% on Reyataz/Norvir/Truvada

 


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