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Author Topic: Bill Gates: Major Funding for vacine. 7/20  (Read 1027 times)

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Offline scaredstraight68

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  • Posts: 75
Bill Gates: Major Funding for vacine. 7/20
« on: July 20, 2006, 01:49:39 AM »
If someone wants to post this in the living with forum they can.  I didn't think I should.  Anyway, I work for a paper and this story will be going tomorrow. 

By LAWRENCE K. ALTMAN
N.Y. Times News Service
SEATTLE ó The Bill and Melinda Gates Foundation awarded more than a quarter of a billion dollars on Wednesday to researchers in 19 countries to speed the lagging development of an HIV vaccine.
The grants are the largest private investment in making such a vaccine, the foundation said. They represent a significant shift in emphasis, to large-scale collaborative projects instead of small teams of researchers working independently.
The money will be given over five years to 16 scientific teams, including two New York groups. The scientists applied for the grants before Warren E. Buffett announced last month that he was giving $31 billion to the Gates Foundation.
The Gates Foundation has made development of an effective vaccine against HIV, the virus that causes AIDS, a major goal, and the new grants bring to $528 million the foundationís investment for this purpose. By contrast, the National Institutes of Health has spent $3.4 billion since the 1980s to develop a vaccine.
A vaccine to fight HIV, the human immunodeficiency virus, is the best hope to control the AIDS epidemic, health officials and experts say. But that hope has been frustrated again and again.
In 1984, Margaret M. Heckler, President Ronald Reaganís health and human services secretary, and Dr. Robert Gallo, a discoverer of the virus, predicted an HIV vaccine by 1986.
Although more than 30 experimental HIV vaccines have been tested in people, only one has completed full-scale testing. That vaccine, Aidsvax, made by VaxGen, failed in a large trial that ended in 2003.
Until now, most HIV vaccine research has been conducted by small independent teams. But the new grants are being structured to encourage the 165 scientists receiving them to join forces. The goal is to overcome major immunologic and other scientific hurdles that hinder development of such a vaccine.
The body can invoke two types of immune reactions to defend against dangerous infectious agents.
One way is to produce neutralizing antibodies, which are proteins that bind like a lock and key to areas on the infectious agent.
A second way, cellular immunity, is to produce T-cells that seek and destroy infected cells.
Most licensed vaccines work by stimulating the body to make neutralizing antibodies. But experimental HIV vaccines have failed to produce such antibodies. The virusí propensity to mutate and produce different genetic subtypes will require an effective vaccine to produce antibodies that can neutralize a wide range of strains.
The foundation said an effective vaccine might also have to stimulate T-cell production.
Six grants will focus on ways to develop cellular immunity.
Five grants will go to identifying new techniques to develop novel vaccines that produce neutralizing antibodies.
The remaining five grants are for creating central laboratories and information analysis facilities so that all the grant recipients can openly share data.
« Last Edit: July 21, 2006, 01:17:40 AM by scaredstraight68 »

Offline scaredstraight68

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Re: Bill Gates: Major Funding for vacine. 7/20
« Reply #1 on: July 21, 2006, 01:17:50 AM »
bump

Offline ImagineFL

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Re: Bill Gates: Major Funding for vacine. 7/20
« Reply #2 on: July 23, 2006, 10:14:05 PM »
That's great to hear... I cut and pasted it into emails for several of my friends that do not frequent this site to often.  Thanks for that info!

Patsy

 


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