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Author Topic: Grapefruit  (Read 2812 times)

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Offline BlueMoon

  • Member
  • Posts: 665
  • Calling from the Fun House
Grapefruit
« on: May 10, 2008, 02:34:44 PM »
When my medications (Truvada/Reyataz/Norvir) were prescribed, the doctor gave me handouts for each.  I've misplaced them but recall that one said to not have grapefruit or grapefruit juice with that particular med (I forget which one).  Since then I've been unable to find a similar warning in any literature.  Does anyone know for sure about that?  I'm also taking Bactrim DS but I'm pretty sure it wasn't that.

The reason I'm asking is that I really want to have the swordfish at the restaurant we're visiting tonight, but it's marinated in grapefruit juice.    :P
...................VL.....CD4.....%
-----------------------------------------
08/10-- ......<40.....290.....42
05/10-- ......<48.....290.....46
02/10-- ......<48.....481.....44
10/09-- ......<48.....277.....46
07/09-- ......<48.....300.....38
05/09-- ........51.....449.....39
03/09-- Added Isentress
02/09-- ........65.....299.....34
11/08-- ........62.....242.....40
08/08-- ........66.....212.....29
05/08-- ......202.....217.....27
03/08-- ....5210.....187.....21
02/08-- Began Truvada/Reyataz/Norvir
12/07-- 273,000.....157.....22
11/07-- 229,000.....209.....22
10/07-- Diagnosis

It's a complex world.

Offline bear60

  • Member
  • Posts: 4,104
Re: Grapefruit
« Reply #1 on: May 10, 2008, 02:46:19 PM »
Hi
Here are several previous threads on the subject of grapefruit :
http://forums.poz.com/index.php?topic=20659.0

http://forums.poz.com/index.php?topic=17829.0

Its possible to enter a keyword into the search feature you find in the left hand column of the forums page, and it will take you to a number of possible results for that word.

Poz Bear Type in Philadelphia

Offline BlueMoon

  • Member
  • Posts: 665
  • Calling from the Fun House
Re: Grapefruit
« Reply #2 on: May 10, 2008, 04:43:21 PM »
Thanks Bear60, that's what I needed to know.  I checked the med lessons but didn't think to search the forums. 

It's a bit disturbing that the info wasn't included in the flyers I got with my meds.  I'm fond of pink grapefruit and would have been eating it all along if I hadn't read that one handout in the doctor's office.

I still may chance it tonight.  Maybe the mercury in the fish will neutralize the grapefruit.    ;D
...................VL.....CD4.....%
-----------------------------------------
08/10-- ......<40.....290.....42
05/10-- ......<48.....290.....46
02/10-- ......<48.....481.....44
10/09-- ......<48.....277.....46
07/09-- ......<48.....300.....38
05/09-- ........51.....449.....39
03/09-- Added Isentress
02/09-- ........65.....299.....34
11/08-- ........62.....242.....40
08/08-- ........66.....212.....29
05/08-- ......202.....217.....27
03/08-- ....5210.....187.....21
02/08-- Began Truvada/Reyataz/Norvir
12/07-- 273,000.....157.....22
11/07-- 229,000.....209.....22
10/07-- Diagnosis

It's a complex world.

Offline J.R.E.

  • Member
  • Posts: 7,214
  • Joined Dec-2003 Living positive, since 1985.
Re: Grapefruit
« Reply #3 on: May 10, 2008, 08:58:26 PM »

The reason I'm asking is that I really want to have the swordfish at the restaurant we're visiting tonight, but it's marinated in grapefruit juice.    :P


I would say dinner sounds fantastic !!  Enjoy!  I wouldn't worry...


Ray
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 8/2514,  t-cells are at 402, Viral load <40

 Current % is at 11%

  
 62 years young.

Offline hivsweden

  • Member
  • Posts: 81
Re: Grapefruit
« Reply #4 on: May 12, 2008, 04:03:50 PM »
The keyword to look for re. grapefruit is interactions with isoenzyme CYP3A4. Sustiva and Truvada are two medications that are boosted if grapefruit is eaten. (Sustiva + fatty foods + grapefruit = A very stange drunken sensation for instance)

Offline Miss Philicia

  • Member
  • Posts: 24,210
  • celebrity poster, faker & poser
Re: Grapefruit
« Reply #5 on: May 12, 2008, 04:10:48 PM »
I think I will eat a grapefruit today.
"Iíve slept with enough men to know that Iím not gay"

Online BT65

  • Global Moderator
  • Member
  • Posts: 9,974
Re: Grapefruit
« Reply #6 on: May 13, 2008, 09:38:18 AM »
I used to love red grapefruit, but I can't eat them with my thyroid med or my cholesterol med. 
I've never killed anyone, but I frequently get satisfaction reading the obituary notices.-Clarence Darrow

Offline Miss Philicia

  • Member
  • Posts: 24,210
  • celebrity poster, faker & poser
Re: Grapefruit
« Reply #7 on: May 13, 2008, 11:27:44 AM »
Seriously -- am I to believe that a simple indulgence of ONE red grapefruit each month is going to fuck things up?  Sorry, but I refuse to live that way.  I think these warnings are for people who would eat grapefruit and/or juice on a daily basis.
"Iíve slept with enough men to know that Iím not gay"

Offline Okealyshire

  • Member
  • Posts: 139
Re: Grapefruit
« Reply #8 on: May 13, 2008, 10:20:22 PM »
I think these warnings are for people who would eat grapefruit and/or juice on a daily basis.

Twice now, my doc has said that I can ignore most such warnings; the negative interactions are pretty rare, apparently. The only combinations he's specifically called out are PIs with St John's Wort and PIs with milk thistle. Curiously, he also said that I don't have to worry at all about PIs and ED drugs (heh, how'd he know?). "Indulge yourself" was, I recall, his exact phrase. :)
« Last Edit: May 13, 2008, 11:07:26 PM by Okealyshire »

Offline aztecan

  • Member
  • Posts: 5,399
  • 29 years positive, 57 years a pain in the butt
Re: Grapefruit
« Reply #9 on: May 13, 2008, 10:43:50 PM »
I don't eat grapefruit, but I do take milk thistle.

I've taken it for years without ill effect.

But, my doc specifically warned me off of grapefruit because ot the PI I take and the statin.

HUGS,

Mark
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline BlueMoon

  • Member
  • Posts: 665
  • Calling from the Fun House
Re: Grapefruit
« Reply #10 on: May 14, 2008, 05:10:49 PM »
I used to love red grapefruit, but I can't eat them with my thyroid med or my cholesterol med. 

Yes, it appears that grapefruit affects quite a few different meds.    :-[

Maybe an occasional grapefruit is ok, but I know only what the experts tell me, and as an AIDS n00b I'm focussed on adherence.  I'm resistant to NNRTIs right out of the gate.  I don't feel that I can afford to take a cavalier attitude toward the advice of the people who make and administer my meds.  So, no grapefruit for me.  Now if they tell me no strawberries, there's gonna be trouble. 

Despite that, I think I still may have had that swordfish the other night, but it wasn't on the menu.  Another dilemma dodged.
...................VL.....CD4.....%
-----------------------------------------
08/10-- ......<40.....290.....42
05/10-- ......<48.....290.....46
02/10-- ......<48.....481.....44
10/09-- ......<48.....277.....46
07/09-- ......<48.....300.....38
05/09-- ........51.....449.....39
03/09-- Added Isentress
02/09-- ........65.....299.....34
11/08-- ........62.....242.....40
08/08-- ........66.....212.....29
05/08-- ......202.....217.....27
03/08-- ....5210.....187.....21
02/08-- Began Truvada/Reyataz/Norvir
12/07-- 273,000.....157.....22
11/07-- 229,000.....209.....22
10/07-- Diagnosis

It's a complex world.

Offline sharkdiver

  • Member
  • Posts: 1,350
Re: Grapefruit
« Reply #11 on: May 14, 2008, 07:28:20 PM »
Despite that, I think I still may have had that swordfish the other night, but it wasn't on the menu.  Another dilemma dodged.

oh my what about the mercury toxity.

 


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