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Author Topic: Second Generation of NNRTI's poised for treatment naive studies  (Read 1650 times)

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Offline J.R.E.

  • Member
  • Posts: 7,213
  • Joined Dec-2003 Living positive, since 1985.
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 8/2514,  t-cells are at 402, Viral load <40

 Current % is at 11%

  
 62 years young.

Offline Patrick

  • Member
  • Posts: 86
  • Where the determination is, the way can be found.
Re: Second Generation of NNRTI's poised for treatment naive studies
« Reply #1 on: January 13, 2008, 03:08:10 PM »
Good news here too.  I believe there are four new drugs mentioned in here that will be hitting the market between 2008-2012 that all offer better barriers to resistence than Sustiva and Viramune, but less side-effects.  Another step forward, and more options for all of us.

With progress like this, I feel that in 10 years, drug regimens for HIV will have advanced to the point where mutation around them will be so difficult as to be almost a non-issue with persons who adhere well to the regimens.  Side-effects will be minimal or none.  Hopefully having HIV can eventually be reduced to simply having to take some pills in the morning and then that's it.  No side-effects (short or long term) and little to no viral resistance to the regimen.

I think this will be the reality of cutting edge HIV therapy around the year 2020.  Articles like this show that we continue to move in that direction.
Seroconversion - late October 07
11/14/07 - CD4 190   VL >750,000
11/14/07 - Started Truvada & Kaletra
12/5/07 - CD4 851     VL 710
2/19/08 - CD4 604     VL Undetectable
5/8/08 -   CD4 829     VL Undetectable
8/12/08 - CD4 915     VL 80 (blip)
11/11/08 - CD4 967    VL Undetectable

Offline tucker

  • Member
  • Posts: 35
Re: Second Generation of NNRTI's poised for treatment naive studies
« Reply #2 on: January 21, 2008, 01:51:21 PM »
that would be wonderful, and it is what I am hoping for, myself.  I am still treatment naive... so starting meds has me kind of nervous.  Really hoping to keep that at bay for another couple of years...  I am amazed and grateful for the amount of resources being devoted to combatting this bug.
confirmed diagnosis 10.1.07
10/07  cd4 504 vl 40,000
1/08  cd4 524 vl 73,000
4/08  cd4 484 vl 48,060
6/02/08 started Truvada, Reyetaz, Norvir
7/08 cd4 605! vl 400
9/08 cd4 713 vl 175

k103 mutation :(

 


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