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Author Topic: Time changes  (Read 2508 times)

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Offline minismom

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  • Quocumque jeceris stabit
Time changes
« on: December 19, 2007, 08:22:05 AM »
I have always wondered about this.  Here in the states, the time changes twice a year.  In the spring we move the clocks up an hour and in the fall we move it back an hour.  What does this do to med intake times?  If mini takes her first dose of meds at 7:30am in the spring, should we wake her up in the fall at 6:30am to give it to her then back up to 7:30 in the spring so that she's essentially taking meds at the same time regardless of what the clock says?  Honestly, we just keep 7:30 meds at 7:30 even when the time changes.  Can an hour make that much difference?

mum
www.watoto.com
www.MotherBearProject.org
"Whichever way you throw me, i will stand"
"Don't worry about the world coming to an end today...it's already tomorrow in Australia"  Charles Schultz

Offline newbie76

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  • Posts: 238
Re: Time changes
« Reply #1 on: December 19, 2007, 12:21:03 PM »
What I do I adjust gradually moving the time I take the meds of about 15 minutes over the course of 4 days, which in your case would be:
Day 1: 7.30 am as usual
Day 2: 7.15
Day 3: 7.00
Day 4: 6.45
Day 5: 6.30 which should also be the day when the time changes bringing in fact back to 7.30am new time.

I also do it when I travel to mainland Europe which is an hour ahead of us in the UK. In any case my HIV doc told me that in general I have an hour margin either way, which in my case means that I can take my meds between 9.30 and 11.30pm, although generally I try to stick to my usual time of 10.30pm.

I hope it helps.
25th Apr 07: The worst day of my life
27th Apr 07: cd4 202 14%
30th Apr 07: cd4 126 18% VL 110000
19th May 07: Started Truvada/Sustiva
20th Jun 07: cd4 218 25% VL 435
13th Aug 07: cd4 374 20% VL 64
20th Dec 07: cd4 435 24% VL <50
20th Oct 08: cd4 725 31% VL <50
30th Nov 09: cd4 725 30% VL <50
01st Nov 10: cd4 755 33% VL<50
11th Nov 11: cd4 754 32% VL<50
01st May 12: cd4 864 40% VL<50
01st May 13: cd4 615 VL 609 :-/
14th May 13: VL <50

Offline Miss Philicia

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  • celebrity poster, faker & poser
Re: Time changes
« Reply #2 on: December 19, 2007, 12:25:10 PM »
Oh come one.  An hour change isn't going to do anything.  It's like splitting hairs.
"Iíve slept with enough men to know that Iím not gay"

Offline newbie76

  • Member
  • Posts: 238
Re: Time changes
« Reply #3 on: December 19, 2007, 01:46:59 PM »
*blush*

I am still quite new to this and don't want to risk messing things up!
25th Apr 07: The worst day of my life
27th Apr 07: cd4 202 14%
30th Apr 07: cd4 126 18% VL 110000
19th May 07: Started Truvada/Sustiva
20th Jun 07: cd4 218 25% VL 435
13th Aug 07: cd4 374 20% VL 64
20th Dec 07: cd4 435 24% VL <50
20th Oct 08: cd4 725 31% VL <50
30th Nov 09: cd4 725 30% VL <50
01st Nov 10: cd4 755 33% VL<50
11th Nov 11: cd4 754 32% VL<50
01st May 12: cd4 864 40% VL<50
01st May 13: cd4 615 VL 609 :-/
14th May 13: VL <50

Offline minismom

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  • Posts: 2,605
  • Quocumque jeceris stabit
Re: Time changes
« Reply #4 on: December 19, 2007, 02:42:17 PM »
You're not messing anything up!  For several years after mini's diagnosis, we did exactly what you wrote because I was horrified that I'd screw up and mini would get sick.  For the last year, we didn't do the "walk down" with the time and her numbers have stayed fine.  I was asking to make sure that her ud vl wasn't just "lucky" and that it was ok to have her meds off by an hour 2x/year.  I thought it was a legitimate question...goodness knows that I've asked crazier ones than this.

mum
www.watoto.com
www.MotherBearProject.org
"Whichever way you throw me, i will stand"
"Don't worry about the world coming to an end today...it's already tomorrow in Australia"  Charles Schultz

Offline dixieman

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Re: Time changes
« Reply #5 on: December 20, 2007, 03:43:02 PM »
Minismom, Don't worry about it... just be as consistant as you can... the dosage on the newer drugs has a window period sometimes by 24 hours... where theres enough drug in the bodies system... just slowly get it as close as you can... an hour should not make a difference...

Offline Miss Philicia

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  • celebrity poster, faker & poser
Re: Time changes
« Reply #6 on: December 20, 2007, 04:33:44 PM »
24 hours?  Are you sure?  I've not heard of any quite that long.
"Iíve slept with enough men to know that Iím not gay"

Offline vokz

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  • Posts: 391
  • efavirenz junkie
Re: Time changes
« Reply #7 on: December 20, 2007, 04:53:04 PM »
Iíd love to see you find a doctor who will tell you that there is a 24 hour window period on taking any of your meds ;)

Doses on HIV meds are a pretty inexact science and there are huge variations in how fast we each absorb the meds (due to size, diet metabolism etc) so best not to push it much beyond an hour or two, IMHO.

The fact that some drugs (like Sustiva) stay in your blood for a long time arguably makes it even more important that you take your drugs close to schedule .. because the more of a drug there is at significant - but ineffectual non-therapeutic - levels, the more opportunity there is for resistance to develop.

I agree with Philly though, just do a straight adjustment when the clocks go forwards / back (or perhaps have one single half-hour intermediary step, when the clocks go back an hour, if you are really nervous).

Offline Miss Philicia

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  • celebrity poster, faker & poser
Re: Time changes
« Reply #8 on: December 20, 2007, 05:12:06 PM »
Agreed.  I'd definitely not fiddle around with more than a couple hours in either direction.
"Iíve slept with enough men to know that Iím not gay"

Offline sacinsc

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  • Posts: 353
Re: Time changes
« Reply #9 on: December 20, 2007, 06:58:45 PM »
Pharmacist told me not to worry about the hour change, just keep them at the same time. That being said I went ahead and changed by the hour. From 8:30 pm to 7:30 pm. Nothing major for me. But I was told I really have about a 4 hour window with my meds.

Matt
March 07 - Negative
May 07 - Exposed
June 07 - Seroconversion
September 07 - CD4 402 VL 118000 25%
October 07 -     CD4 294 VL 124000 22%
November 07 - Norvir, Triuvada and Reyataz
December 07 -  CD4 355 VL  550 .... guess the meds are working.
January 08 - CD4 446 VL <48 undetectable!
April 08 - CD4 554 VL <48 undetectable!
July 08 - CD4 666 VL <48 undetectable! Hporay...I have devil CD4's

Offline minismom

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  • Quocumque jeceris stabit
Re: Time changes
« Reply #10 on: December 20, 2007, 08:44:46 PM »
Thank you so much for your posts. 

mum
www.watoto.com
www.MotherBearProject.org
"Whichever way you throw me, i will stand"
"Don't worry about the world coming to an end today...it's already tomorrow in Australia"  Charles Schultz

Offline a2z

  • Member
  • Posts: 186
Re: Time changes
« Reply #11 on: December 28, 2007, 04:32:17 PM »
It would be interesting to see a "fudge factor" chart for all HIV meds with min-max ranges for how far off you can be (from the previous day) and still consider the dose to be "not missed" (or not harmful in the case of taking two doses too close together.)

I wonder if even ID Docs agree on windows for the various medicines.
Dates are blood draw dates:
09/21/09: CD 898 27.0% VL 120 - back on track, same meds.High level enzymes, but less so
06/15/09: CD4 478 21.8% VL 1150 - high liver enzymes... looks like I may not be resistant
05/22/09: Fixed insurance, resumed medicine
04/17/09: Ran out of medicine, could not resolve insurance problems
04/01/09: CD4 773 28% VL 120 - high liver enzymes
12/01/08: CD4 514 23% VL 630
10/17/08 started Reyataz, Norvir and Truvada. -- possibly minor neuropathy, but otherwise okay.
9/10/08: CD4 345 17%, VL > 78K
8/18/08: CD4 312 18%, VL > 60K (considering meds)
12/19/07: CD4 550 28% VL > 100K (no meds yet)
Diagnosed 10/23/07

Offline J.R.E.

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  • Posts: 7,099
  • Joined Dec-2003 Living positive, since 1985.
Re: Time changes
« Reply #12 on: December 28, 2007, 05:07:53 PM »
It would be interesting to see a "fudge factor" chart for all HIV meds with min-max ranges for how far off you can be (from the previous day) and still consider the dose to be "not missed" (or not harmful in the case of taking two doses too close together.)

I wonder if even ID Docs agree on windows for the various medicines.

For myself, I always try to take my meds within 45 minutes plus or minus. I normallly take my AM dose ( Viramune and Epzicom) at 8:00 Am. My PM dose  Viramune and Viread, is taken at 8:00 PM.


When I started on meds, just a little over 4 years ago, that was the schedule that worked best for me, according to my work schedule and sleep schedule. And it still works for me.

Bottom line is ADHERANCE !! So, Best thing to do is once you get started on meds, Decide the time factor, of taking those meds, and stick as close to possible to those times. Also, no matter how precise someone is at taking their meds on time, there will be those days, when you may run late, or completely forget a dose.
 From The lessons :

http://www.aidsmeds.com/articles/Adherence_7420.shtml

Take care-----Ray
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 6/4/14,  t-cells are at 423, Viral load <40

 Current % is at 13% 

  
 62 years young.

Offline J.R.E.

  • Member
  • Posts: 7,099
  • Joined Dec-2003 Living positive, since 1985.
Re: Time changes
« Reply #13 on: December 28, 2007, 05:12:42 PM »


Getting back to the time changes. The first year or two, I was making allowances for the "Spring forward -Fall back time changes.

For the meds that I am on, I just continue now, at taking them at the regular time, despite the time changes.


Ray
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 6/4/14,  t-cells are at 423, Viral load <40

 Current % is at 13% 

  
 62 years young.

Offline minismom

  • Member
  • Posts: 2,605
  • Quocumque jeceris stabit
Re: Time changes
« Reply #14 on: December 29, 2007, 09:17:55 AM »
When Mini was in the hospital for 5mths, the hospital was so crazy about her HIV meds that they told me to bring our's from home and put a note in her chart that I would be responsible for giving them to her.  At first, they took the meds that I brought from home and sent them down to the pharmacy in the hospital.  Problem was, they considered "on time" as a range of up to 2hrs either way!  I freaked out and demanded that I get back the meds and give them to her myself.  I had to sign a release, but it made me feel better.  Before you rag me about my paranoia, this began about 8mths after diagnosis.  We are still crazed about times, but we just give her meds at the regular time regardless of the time change.  So far, so good.

Thanks for all the great input.

Mum
www.watoto.com
www.MotherBearProject.org
"Whichever way you throw me, i will stand"
"Don't worry about the world coming to an end today...it's already tomorrow in Australia"  Charles Schultz

 


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