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Author Topic: Just curious  (Read 5274 times)

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Offline aztecan

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  • Posts: 5,400
  • 29 years positive, 57 years a pain in the butt
Just curious
« on: December 20, 2007, 07:30:52 PM »
I was just curious how many people here have never had a genotype test done.

I know I haven't, but then, they weren't around when I started meds.

It seems like many have had this test done at least once. I'm just curious if everyone has had it.


HUGS,

Mark
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline RapidRod

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Re: Just curious
« Reply #1 on: December 20, 2007, 07:32:30 PM »
I had one done before I started meds in 2005.

Offline minismom

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  • Quocumque jeceris stabit
Re: Just curious
« Reply #2 on: December 20, 2007, 07:41:56 PM »
mini had her's after 15mths of various "failed" cocktails, 5mths in the hospital, and 2 surgeries.  I had no idea the test even existed until she was having it.  If I would've known about it, I would've demanded it be done sooner.

Mum
www.watoto.com
www.MotherBearProject.org
"Whichever way you throw me, i will stand"
"Don't worry about the world coming to an end today...it's already tomorrow in Australia"  Charles Schultz

Offline J.R.E.

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  • Joined Dec-2003 Living positive, since 1985.
Re: Just curious
« Reply #3 on: December 20, 2007, 07:46:56 PM »
Mark,

I have never had either one done.


Ray
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 8/2514,  t-cells are at 402, Viral load <40

 Current % is at 11%

  
 62 years young.

Offline Seven

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Re: Just curious
« Reply #4 on: December 20, 2007, 07:55:38 PM »
Nope me neither

Offline anniebc

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Re: Just curious
« Reply #5 on: December 20, 2007, 08:53:21 PM »
Hi Mark

I had one done when I seroconverted in April 2002..this is how I found out I had the same rare K103N mutation as the index patient.

Hugs
Jan :-*
-----------------------------------------------------------------------
Never knock on deaths door..ring the bell and run..he really hates that.

Offline MOONLIGHT1114

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  • Cheech 2.2.94 - 4.23.10 We miss you so much!
Re: Just curious
« Reply #6 on: December 20, 2007, 08:56:58 PM »
I had one done in 2002 after a VL blip 2x in a row.  I was diagnosed poz in 1993, went on meds in 1995.  I switched to PIs in 1996 and then the blips happened in late 2002.  If the doc hadn't hesitantly mentioned a genotype I never would've known either.  Glad I insisted after learning about it bec it turns out I was resistant to the PIs.  been on Sustiva ever since, first with Zerit and Videx, now with Truvada.

~ Cindy
HIV+ since '93, 1/12 - CD4 785 and undet.   WOO-HOO!!

Offline bocker3

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  • You gotta enjoy life......
Re: Just curious
« Reply #7 on: December 20, 2007, 09:26:03 PM »
I had one done in November 2005, just before starting meds.

Mike
Atripla - Started 12/05
Reyataz/Norvir - Added 6/06
Labs - Pre-Meds
Sep05 T=350/25% VL98,559
Nov05 288/18%  47,564
Current Labs
May2013 691/31% <20

Offline megasept

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  • Steven here...
Re: Just curious
« Reply #8 on: December 20, 2007, 09:33:23 PM »
Mark: Not me.

 8)  -megasept

Offline AlanBama

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  • Alabama: the 'other' 3rd World Country!
Re: Just curious
« Reply #9 on: December 20, 2007, 09:46:28 PM »
I've never had one either Mark.   
"Remember my sentimental friend that a heart is not judged by how much you love, but by how much you are loved by others." - The Wizard of Oz

Offline Matty the Damned

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Re: Just curious
« Reply #10 on: December 20, 2007, 09:49:41 PM »
I've had a couple done. I've get the results of the latest one sometime in January.

MtD

Offline ademas

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Re: Just curious
« Reply #11 on: December 20, 2007, 09:53:52 PM »
None here.  They weren't around when I started meds.

I don't think viral load tests were even around when I started the Crixivan trial (not sure about that, though).

You need a detectable viral load to take a genotype test, right?

Offline aztecan

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  • 29 years positive, 57 years a pain in the butt
Re: Just curious
« Reply #12 on: December 20, 2007, 10:01:51 PM »
None here.  They weren't around when I started meds.

I don't think viral load tests were even around when I started the Crixivan trial (not sure about that, though).

You need a detectable viral load to take a genotype test, right?

Actually, it was that requirement that brought this to mind. Rich (Pozattitude) said he was going off meds for a month or so to allow his viral load to build up enough to enable him to have a GART done.

I would probably have to do the same thing because I have had an undetectable viral load since July 1996.

I just wondered how many others have never had the test done. I see now there are a number of us.

Oh, I think you're right. The viral load tests did not become standard of care until either late 1995 or early 1996, I think. I had a couple done in 1995, and I know one was still considered "experimental" because there was concern my insurance wouldn't pay for it. We did it anyway and the insurance never blinked an eye.

I wasn't on the Crix trials, but I was on Crix for 11 years. Does that count?  ;)

HUGS,

Mark
« Last Edit: December 20, 2007, 10:04:39 PM by aztecan »
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline strykern

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  • Oh. I see...
    • Strykern Journey
Re: Just curious
« Reply #13 on: December 20, 2007, 10:09:01 PM »
I have never had one and never discussed with my doctor.  Should I? 
It is what it is...

I am what I am...

Offline ademas

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Re: Just curious
« Reply #14 on: December 20, 2007, 10:12:38 PM »

I wasn't on the Crix trials, but I was on Crix for 11 years. Does that count?  ;)


mmmm...yeah...that counts big time.
 :)

Offline aztecan

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  • 29 years positive, 57 years a pain in the butt
Re: Just curious
« Reply #15 on: December 20, 2007, 10:19:56 PM »
I have never had one and never discussed with my doctor.  Should I? 

Possibly. The test is done routinely nowadays before people start meds to make sure they don't have any inherited resistance.

You just started meds, right? You might want to broach the subject with your doc to get his take on whether one is needed.

HUGS,

Mark
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline strykern

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  • Oh. I see...
    • Strykern Journey
Re: Just curious
« Reply #16 on: December 20, 2007, 10:27:13 PM »
Will do!  Thanks guys!
It is what it is...

I am what I am...

Offline paolo10954

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  • Posts: 57
Re: Just curious
« Reply #17 on: December 20, 2007, 10:34:35 PM »
Hi Mark,

My partner Robert started Sustiva and Truvada which improved his numbers for about 6 months. GART was done when his numbers started to decline and was attributed to an acquired resistance to Sustiva. He then switched to Reyataz/Norvir with Truvada regimen. His numbers continue to climb up steadily.

Just before moving to SF our ID doctor ordered the test for me. This was to determine if we had the same strain, and if I were to start meds, we would have prior knowledge if I have any resistance to any of them. But the test was inconclusive due to not having enough viral load.

Warmest regards,

Paolo
jun03     hiv negative
dec03     tested positive
mar05     cd4 698  vl 23221 no meds
jul05       cd4 660  vl 2962 no meds
dec05     cd4 553  vl 5412 no meds
mar06     cd4 610  vl 3158 no meds
june06    cd4 523  vl 3924 no meds
dec06     cd4 616  vl 1236 no meds
march07  cd4 536  vl 1331 no meds
june07    cd4 486  vl   820 no meds
sept07     cd4 576  vl  380  no meds
aug08     cd4 530  vl 1725 no meds
april09    cd4 428  vl  1059 no meds
july09     cd4 511  vl   533 no meds
jan10      cd4 380  vl  1200 no meds
mar10     cd4 262  vl  2389 no meds
april28, 2010 started on Isentress and Truvada
july10     cd4 340  vl undetectable
nov10     cd4 431  vl undetectable
march11  cd4 350  vl undetectable

Offline leatherman

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Re: Just curious
« Reply #18 on: December 20, 2007, 10:38:15 PM »
after going on and off meds several times through the years because of the side effects, my doctor did one in 2003 as we tried to find a regimen a)I could tolerate and b) that would work. Wouldn't you know out of the 20 something pills a day I was taking, the smallest, easiest to swallow, never-made-me-sick pill of Epivir was the one no longer working.  :o We eventually got it down to 10 pills a day now.  ;)

I've had 5 vl blips through this year, and every time the doctor threathens  ;) these tests to determine which drug to use next; but thankfully every time the blip has leveled back out. :D If I ever have two upward blips in a row, I've get the typing done for sure.

I don't know how I'd feel to going "detectable" on purpose though - it happens enough when I don't try LOL- but no, really, if I had been staying at an undetectable level for a while, I don't think I could go off meds to make my VL rise. Sorry but if it ain't broke, don't fix it.
leatherman (aka mIkIE)


chart from 1992-2013; updated 2/09/13  Reyataz/Norvir/Truvada

Offline David_CA

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Re: Just curious
« Reply #19 on: December 20, 2007, 11:03:14 PM »
Hi Mark,

I had both genotype and phenotype tests back when I had my initial VL and CD4 tests.  I know my hubby has had a genotype, but I'm not sure about a phenotype.

David
Black Friday 03-03-2006
03-23-06 CD4 359 @27.4% VL 75,938
06-01-06 CD4 462 @24.3% VL > 100,000
08-15-06 CD4 388 @22.8% VL >  "
10-21-06 CD4 285 @21.9% VL >  "
  Atripla started 12-01-2006
01-08-07 CD4 429 @26.8% VL 1872!
05-08-07 CD4 478 @28.1% VL 740
08-03-07 CD4 509 @31.8% VL 370
11-06-07 CD4 570 @30.0% VL 140
02-21-08 CD4 648 @32.4% VL 600
05-19-08 CD4 695 @33.1% VL < 48 undetectable!
08-21-08 CD4 725 @34.5%
11-11-08 CD4 672 @39.5%
02-11-09 CD4 773 @36.8%
05-11-09 CD4 615 @36.2%
08-19-09 CD4 770 @38.5%
11-19-09 CD4 944 @33.7%
02-17-10 CD4 678 @39.9%  
06-03-10 CD4 768 @34.9%
09-21-10 CD4 685 @40.3%
01-10-11 CD4 908 @36.3%
05-23-11 CD4 846 @36.8% VL 80
02-13-12 CD4 911 @41.4% VL<20
You must be the change you want to see in the world.  Mahatma Gandhi

Offline Basquo

  • Member
  • Posts: 3,260
Re: Just curious
« Reply #20 on: December 20, 2007, 11:29:28 PM »
I've never had one.

Offline jabez

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  • Posts: 97
Re: Just curious
« Reply #21 on: December 20, 2007, 11:46:34 PM »
Yes sir, I had one. 

My initial labs were absolutely HORRIBLE (very low CD4 count and a viral load of about 500,000).  I wanted to start meds immediately, but my doctor made me wait a week or ten days while she ran a genotype test.  At the time, I was angry about having to wait for the test results.  But now I'm glad that we did it, because I learned more about my treatment options.
Sept 2007 -- CD4 = 68; VL = 469,000
Started Atripla Sept 21, 2007
Nov 2007-CD4=217;VL=332
Feb 2008-CD4=237;VL=<50
Apr 2008-CD4=271;VL=66
Aug 2008-CD4=440;VL=52
Jan 2009-CD4=403;VL=61
May 2009-CD4=480;VL=129
Sep 2009-CD4=376;VL<40
Jan 2010-CD4=476;VL<40
Jul 2010-CD4=539;VL<40
Jan 2011-CD4=461;VL=53
Jul 2011-CD4=515;VL<20
Jan 2012-CD4=506;VL=54
Aug 2012-CD4=440;VL=21
Jan 2013-CD4=447;VL=<20
Jul 2013-CD4=406; VL=<20
Feb 2014-CD4=450; VL=<20
Aug 2014-CD4=535; VL=<20

Offline jason304

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  • There is so much more to me than my status.
Re: Just curious
« Reply #22 on: December 20, 2007, 11:48:36 PM »
Never had a geno type test done yet--but not on meds

Offline next2u

  • Member
  • Posts: 1,762
Re: Just curious
« Reply #23 on: December 21, 2007, 12:03:06 AM »
i see my doc in jan for the second time. i will have him run the tests then. i haven't had a cd4 percent also. damn it, should the phenotype be done as well?
midapr07 - seroconversion
sept07 - tested poz
oct07 cd4 1013; vl 13,900; cd4% 41
feb08 cd4  694;  vl 16,160; cd4% 50.1
may08 cd4 546; vl 91,480; cd4% 32
aug08 cd4 576; vl 48,190; cd4% 40.7
dec08 cd4 559; vl 63,020; cd4% 29.4
feb09 cd4 464; vl 11,000; cd4% 26
may09 cd4 544; vl 29,710; cd4% 27.2
oct09 cd4 ...; vl 23,350; cd4% 31.6
mar10 cd4 408; vl 59,050; cd4% 31.4
aug10 cd4 328; vl 80,000; cd4% 19.3 STARTED ATRIPLA
oct10 cd4 423; vl 410 ;); cd4% 30.2
jun11 cd4 439; vl <20 ;); cd4% 33.8 <-Undetectable!
mar12 cd4 695; vl ud; cd4% 38.6
jan13 cd4 738; vl ud; cd4% 36.8
aug13 cd4 930; vl ud; cd4% 44.3
jan14 cd4 813; vl ud; cd4% 42.8
may14 cd4 783; vl *; cd4%43.5

Offline joemutt

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Re: Just curious
« Reply #24 on: December 21, 2007, 01:59:30 AM »
I havent. Hugs.

Offline BT65

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Re: Just curious
« Reply #25 on: December 21, 2007, 06:59:29 AM »
Mark, I've had two genotypes done, but I am currently waiting on a Phenotype's results.  The doc wanted to run the pheno this time as it is more accurate.  The last genotype I had done was a little over a year ago.  As soon as my doc gets the results of the pheno back, I will be starting on a new regimen, which the doc said will most likely include Isentress. 
I've never killed anyone, but I frequently get satisfaction reading the obituary notices.-Clarence Darrow

Offline Teresa

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Re: Just curious
« Reply #26 on: December 21, 2007, 07:07:11 AM »
Hubby hasnt had a geno test done.
Hubby HIV+ 5/5/06
CD4:320
  %: 26.7
 VL: <20
Atripla (started it 8/24/06)
 

Offline Peter6836

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  • Me and my Granddaughter Noa
Re: Just curious
« Reply #27 on: December 21, 2007, 07:26:44 AM »
First thing my Doctor did, after I was diagnosed.  I feel blessed to have a very thorough doctor who is quite up on things. Not only that he sits and talks to me and has gotten to know me personally as well.
Best of everything, Happy Holidays!!!!
Peter

Offline oh my...

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Re: Just curious
« Reply #28 on: December 21, 2007, 09:12:08 AM »
My id doc ran one as part of the initial bloodwork I got after seroconverting.

Offline Miss Philicia

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Re: Just curious
« Reply #29 on: December 21, 2007, 11:40:59 AM »
Considering that I never was able to achieve viral suppression until last year, though I've been on meds for almost 15 years, I've had quite a few done.  There was also a lot of hand wringing by all of my doctors.
"Iíve slept with enough men to know that Iím not gay"

Offline Hard Times

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Re: Just curious
« Reply #30 on: December 21, 2007, 12:08:06 PM »
i'm on my 3rd genotype test,   i seen the vampire on the 17th, she took 10 TUBES of blood !
& i'm still some what drained today !    the test is worth it !

tommy
Your Body Is What You Are.
Your Soul Is Who You Are.

Offline sacinsc

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Re: Just curious
« Reply #31 on: December 21, 2007, 12:50:23 PM »
When I first was diagnosed I had a genotype done with my first set of labs. It was a request of my doctor to know what meds would be wasted on me. Luckily I had no mutations so I am all good :)

Matt
March 07 - Negative
May 07 - Exposed
June 07 - Seroconversion
September 07 - CD4 402 VL 118000 25%
October 07 -     CD4 294 VL 124000 22%
November 07 - Norvir, Triuvada and Reyataz
December 07 -  CD4 355 VL  550 .... guess the meds are working.
January 08 - CD4 446 VL <48 undetectable!
April 08 - CD4 554 VL <48 undetectable!
July 08 - CD4 666 VL <48 undetectable! Hporay...I have devil CD4's

Offline pozattitude

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Re: Just curious
« Reply #32 on: December 21, 2007, 01:57:31 PM »
I had one done back in 1999 ( I think, maybe it was 2000 or 2001...I can't keep track of time lines anymore) and  I will have a new one done in January

Rich
POSITIVE PEDALERS... We are a group of people living with HIV/AIDS, eliminating stigma through our positive public example.

Offline StrongGuy

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Re: Just curious
« Reply #33 on: December 23, 2007, 11:57:50 PM »
I never had one done.

When I started I didn't have the best of docs (meant well, but a little behind) and he didn't even offer the option (I'm not even sure the test was available as I was behind myself back then). In hindsight wish I had had known to inquire about it because my doc was not happy with how my first combo was taking too long to reach consistent undetectable so he switched me to a PI backbone.

Switched out of the PI since then (back to Sustiva which I feared I may have had some resistance to but new doc didn't think so and he was right) and it has worked just fine. Been undetectable for years on PI and now the NNRTI so my doc assures me it is unlikely I have any major resistance issues based on my response to the regimens I have been on which is fine with me.




« Last Edit: December 24, 2007, 12:00:51 AM by StrongGuy »
"Get your medical advice from Doctors or medical professionals who you trust and know your history."

"Beware of the fortune teller doom and gloomers who seek to bring you down and are only looking for company, purpose and validation - not your best physical/mental interests."

"You know you all are saying that this is incurable. When the real thing you should be saying is it's not curable at the present time' because as we know, the great strides we've made in medicine." - Elizabeth Edwards

Offline Ann

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Re: Just curious
« Reply #34 on: December 24, 2007, 06:51:36 AM »
I've never had one done and I probably won't until such time as I've been on meds for a while and start showing detectable. This is because the man from whom I aquired my virus (I know, it's a mouthful!) had one done when he started treatment and had no resistance to anything. We go to the same clinic.

We discussed this last year when I had my first ever clear downward trend. My doc ran the test they do nowdays to find out if you can take abacavir without running the risk of the allergic reaction some people get, but it was decided I didn't need geno/pheno testing.

Still not on meds after ten years poz - my downward trend reversed itself - and it looks like I'll get another few years med-free.

~whew~

Ann
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline penguin

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Re: Just curious
« Reply #35 on: December 24, 2007, 06:58:41 AM »
for hiv,probably around 8 genotypes, 8 or 9 phenotypes. what can i say, i'm special.

ann, you have had a genotype, for your hep c..just in case you were feeling left out  :)

kate

Offline Ann

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Re: Just curious
« Reply #36 on: December 24, 2007, 07:12:10 AM »

ann, you have had a genotype, for your hep c..just in case you were feeling left out  :)

kate

YAY! You're absolutely correct, Kate, I did have an HCV genotype done. I was a 3a. ;)

Ann
Condoms are a girl's best friend

Condom and Lube Info  



"...health will finally be seen not as a blessing to be wished for, but as a human right to be fought for." Kofi Annan

Nymphomaniac: a woman as obsessed with sex as an average man. Mignon McLaughlin

HIV is certainly character-building. It's made me see all of the shallow things we cling to, like ego and vanity. Of course, I'd rather have a few more T-cells and a little less character. Randy Shilts

Offline LatinAlexander

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Re: Just curious
« Reply #37 on: December 24, 2007, 08:16:38 AM »
It just became a standard of care in my country this year. I was lucky, because a pharma company was running a study about new infections, and my ID Doc got me on it. So they ran the genotype.

Alex
Poz since Jul 19 2006
Initial numbers : CD4-250 VL 3500
First labs after HAART (Dec 04-2006) : CD4-432 VL-<40 (Undetectable)  cd4%=25.11%
Started HAART: Combivir+Efavirenz Aug 26 7:38 pm
Feb 08 2007 - Gradually stopping HAART cause of Myalgia. Protecting Efavirenz. Stopped Efavirenz, ahead with Combivir....
February 17 Combivir stopped.
April 3 -07 : Started ddi+3tc+efavirenz...
Gay and positive (What a lack of Identity...:) )
Looking for my Ben....

Offline heartforyou

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Re: Just curious
« Reply #38 on: December 24, 2007, 08:25:45 AM »
Hi Mark,

As I have had to deal with resistance a lot, I have had several genotypes done.
They showed that i am resistant to most..... but always had new ones available just in time.

Merry Christmas baby

hermie
Diagnosed in 1987 and still kicking
Viread, Kivexa (Epzicom),Viramune once daily

Happiness is the freedom of breathing fresh air every day.

Offline northernguy

  • Member
  • Posts: 1,347
Re: Just curious
« Reply #39 on: December 24, 2007, 12:26:33 PM »
I'm glad I'm not alone - I've never had one done.

I asked my doc and his feeling was that since less than 2% of his large HIV practice had resistance issues, he didn't think it was necessary.
Apr 28/06 cd4 600 vl 10,600 cd% 25
Nov 8/09 cd4 510 vl 49,5000 cd% 16
Jan 16/10 cd4 660 vl 54,309 cd% 16
Feb 17/10 Started Atripla
Mar 7/10 cd4 710 vl 1,076 cd% 21
Apr 18/10 cd4 920 vl 268 cd% 28
Jun 19/10 cd4 450 vl 60 cd% 25
Aug 15/10 cd4 680 vl 205 cd% 27
Apr 3/11 cd4 780 vl <40 cd% 30
Jul 17/11 cd4 960 vl <40 cd%33
April 15/12 cd4 1,010 vl <40 cd% 39
April 20/12 Switched to Viramune + Truvada
Aug 2/12 cd4 1040, vl <40, cd% 38
Oct 19 cd4 1,110 vl <40 cd% 41

 


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