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Author Topic: CD4 count not CD4 % to guide treatment decisions say some Italians  (Read 2546 times)

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Offline newt

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Use CD4 cell count, not CD4 cell percentage to guide treatment decisions in all patients with HIV

Full title of report is Use CD4 cell count, not CD4 cell percentage to guide treatment decisions in all patients with HIV, even those with cirrhosis

"CD4 cell counts and not CD4 cell percentages should be used to guide antiretroviral treatment decisions in all HIV-positive patients, including those with cirrhosis, according to Italian research published in the September 1st edition of Clinical Infectious Diseases.

"It had been hypothesised that CD4 cell percentages would provide a more accurate guide to the immune status of HIV-infected patients with cirrhosis, but analysis of almost 6,000 patients in a large Italian cohort revealed that CD4 cell count was a more accurate predictor than CD4 percentage of a patient’s risk of progressing to AIDS."

etc

- matt
"The object is to be a well patient, not a good patient"

Offline Matty the Damned

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Re: CD4 count not CD4 % to guide treatment decisions say some Italians
« Reply #1 on: August 15, 2007, 04:25:56 AM »
Cheers Matt! A most interesting read.

MtD

Offline J220

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Re: CD4 count not CD4 % to guide treatment decisions say some Italians
« Reply #2 on: August 15, 2007, 10:00:51 AM »
Interesting, this is what my doctor told me from day one (Feb '06). He always seemed dismissive of the percentage values, and in fact as of right now I have no idea what they are, he always focuses on CD4 and VL values exclusively.
"Hope is my philosophy
Just needs days in which to be
Love of Life means hope for me
Born on a New Day" - John David

Offline milker

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Re: CD4 count not CD4 % to guide treatment decisions say some Italians
« Reply #3 on: August 15, 2007, 02:10:09 PM »
Interesting study, thanks for sharing!

Millker.
mid-dec: stupid ass
mid-jan: seroconversion
mid-feb: poz
mar 07: cd4 432 (35%) vl 54000
may 07: cd4 399 (28%) vl 27760
jul 07: cd4 403 (26%) vl 99241
oct 07: cd4 353 (24%) vl 29993
jan 08: cd4 332 (26%) vl 33308
mar 08: cd4 392 (23%) vl 75548
jun 08: cd4 325 (27%) vl 45880
oct 08: cd4 197 (20%) vl 154000 <== aids diagnosis
nov 2 08 start Atripla
nov 30 08: cd4 478 (23%) vl 1880 !!!!!!!!!!!!!!!!!!!!!!!!!!
feb 19 09: cd4 398 (24%) vl 430 getting there!
apr 23 09: cd4 604 (29%) vl 50 woohoo :D :D
jul 30 09: cd4 512 (29%) vl undetectable :D :D
may 27 10: cd4 655 (32%) vl undetectable :D :D

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Offline northernguy

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Re: CD4 count not CD4 % to guide treatment decisions say some Italians
« Reply #4 on: August 16, 2007, 12:56:45 AM »
My doc barely mentions percentages.
Apr 28/06 cd4 600 vl 10,600 cd% 25
Nov 8/09 cd4 510 vl 49,5000 cd% 16
Jan 16/10 cd4 660 vl 54,309 cd% 16
Feb 17/10 Started Atripla
Mar 7/10 cd4 710 vl 1,076 cd% 21
Apr 18/10 cd4 920 vl 268 cd% 28
Jun 19/10 cd4 450 vl 60 cd% 25
Aug 15/10 cd4 680 vl 205 cd% 27
Apr 3/11 cd4 780 vl <40 cd% 30
Jul 17/11 cd4 960 vl <40 cd%33
April 15/12 cd4 1,010 vl <40 cd% 39
April 20/12 Switched to Viramune + Truvada
Aug 2/12 cd4 1040, vl <40, cd% 38
Oct 19 cd4 1,110 vl <40 cd% 41

Offline billy

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Re: CD4 count not CD4 % to guide treatment decisions say some Italians
« Reply #5 on: August 17, 2007, 03:58:24 PM »
My doc here in Greece said... that I should not give that importance to CD4%...
CD4 total cell numbers sre more important... it's the way the treat here in Greece.

Well, I hope docs know it better...
09/07: VL 2.200.000
12/07: Kaletra-Kivexa
01/08: T4 720 VL<50
04/08: T4 1.350 VL<50
09/08: T4 1.465 VL<50
02/09: T4 1.230 VL<50
07/09: T4 1.150 VL<50
12/09: T4 1.110 VL<50
06/10: T4 1.600 VL<50
11/10: T4 1.390 VL<50
05/11: T4 700 VL<50
07/11: T4 1.035 VL<50
02/12: T4 1.010 VL<50
06/12: T4 965 VL<50
11/12: T4 850 VL<50
04/13: T4 1220 VL<50
09/13: T4 1100 VL<50
02/14: T4 1120 VL<50

Offline JamieD

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Re: CD4 count not CD4 % to guide treatment decisions say some Italians
« Reply #6 on: August 17, 2007, 05:21:41 PM »
My doc barely mentions percentages.

Same here. I wish I didn't know the percentage. :-/ My doctor only told me it because I asked. It was 8.6%.

tendai

  • Guest
Re: CD4 count not CD4 % to guide treatment decisions say some Italians
« Reply #7 on: August 22, 2007, 06:20:43 AM »
same here, they say they only use the percentage when treating children and only concentrate ion the absolute count.  we dont do viral loads though, they have to be sent to South Africa and that involves foreign currency which we dont have. 

Jamie mine was 7% last time (May) and i was in absolute terror that i was going to collapse and die of AIDS anyday but i'm still ok.

 


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