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Author Topic: Any J&J gene therapy news?  (Read 2138 times)

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Offline hahaha

  • Member
  • Posts: 123
Any J&J gene therapy news?
« on: August 11, 2007, 11:44:39 AM »
I hate to bring up this again.   But does anyone know about J&J gene therapy news of phase II? it shall be out in Feb this year.  Obviously it just disappear for a long long time.   There must be something wrong, isn't it? Mutation of virus cause the gene therapy fail or what?  Does anybody know?
Aug 9, 2006 Get infected in Japan #$%^*
Oct 2006 CD4 239
Nov 2006 CD4 299 VL 60,000
Dec 1, Sustiva, Ziagan and 3TC
Jan 07, CD4 400

Offline Jake72

  • Member
  • Posts: 145
Re: Any J&J gene therapy news?
« Reply #1 on: August 11, 2007, 09:50:22 PM »
This is the J&J/Tibotec thing, right? 

I found this article from July 30, 2007 that does mention the gene therapy study but doesn't say a whole lot about it:

"Tibotec has even invested in a long-shot gene-therapy experiment to produce a line of immune cells that are themselves immune to HIV and its effects. This approach has been kicked around casually for more than 15 years, but Tibotec's is the single serious study up and running. In fact, Tibotec, along with Merck, is the only company in all of pharma looking for the cure. "

http://www.pharmexec.com/pharmexec/article/articleDetail.jsp?id=446937&sk=&date=&pageID=7

So I guess this means it's still going on? 

Offline NYCguy

  • Member
  • Posts: 180
Re: Any J&J gene therapy news?
« Reply #2 on: August 13, 2007, 02:22:25 AM »
there is another thread where this was discussed extensively.  as far as I know still no news.  J220 was in touch with someone in the study who was also in the press some time  ago and I asked to him see if he could reach the guy again, but so far I don't think he's been able.  This has been frustrating as there were high expectations for the outcome of this...  maybe write to someone at Tibotec?
11/9/06 = #$%^&!
sometime early Dec 2006:
CD4 530 20%/VL >250,000 (&*$$%!!)
started Reyataz300mg/Norvir/Truvada 12-27-06.
1/30/07 CD4 540 30%/VL <400
4/07 CD4 600+ 33%/VL <50
6/9/07 CD4 720 37%/VL <50
10/15/07 CD4 891 (!) %? VL <50
1/2010 CD4 599 (37%) VL<50 (drop due to acute HCV)
9/2010 - looks like HCV is gone for good! And I'm finally drinking again, thank GOD
2013 - considering a switch to Stribild. but I love my Kidneys (but I hate farting all the time!)...
June 2013 - switched to Stribild.  so far so good...

Offline FiercenBed

  • Member
  • Posts: 183
Re: Any J&J gene therapy news?
« Reply #3 on: August 15, 2007, 06:22:35 PM »
thier web site is very interesting. sez there are 2 phase IIa trials completed and one IIb trial ongoing. checking out the adobe poster.

i just dont understand why these things just drop outa sight?

Offline NYCguy

  • Member
  • Posts: 180
Re: Any J&J gene therapy news?
« Reply #4 on: August 15, 2007, 10:25:37 PM »
wrote wrote a note to tibotec via their site, so we'll see if any response comes in. 
11/9/06 = #$%^&!
sometime early Dec 2006:
CD4 530 20%/VL >250,000 (&*$$%!!)
started Reyataz300mg/Norvir/Truvada 12-27-06.
1/30/07 CD4 540 30%/VL <400
4/07 CD4 600+ 33%/VL <50
6/9/07 CD4 720 37%/VL <50
10/15/07 CD4 891 (!) %? VL <50
1/2010 CD4 599 (37%) VL<50 (drop due to acute HCV)
9/2010 - looks like HCV is gone for good! And I'm finally drinking again, thank GOD
2013 - considering a switch to Stribild. but I love my Kidneys (but I hate farting all the time!)...
June 2013 - switched to Stribild.  so far so good...

 


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