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Author Topic: Sustiva/Combivir to Atripla - anyone else?  (Read 2165 times)

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Sustiva/Combivir to Atripla - anyone else?
« on: June 30, 2007, 03:35:24 PM »
So after a year and a half on Combivir and Sustiva, I have really had it with the nausea.  The dreams and nausea have really been my only side effects.  My viral load has been undetectable for over a year, and my CD4 count keeps going up, so the drugs are working.  I take Zofran to battle the nausea and it works most of the time.  I have lost thirty pounds since January though, without trying.  I am assuming that my nausea has caused me to eat less without even noticing.  Kidney and liver functions are fine too.

I visited my doctor last week, and he will take me off the Combivir and Sustiva, switching me to Atripla only.  I am off work this week on vacation and I'm expecting new meds by Friday or Saturday.  I am SO afraid of the unknown...how will it make me feel.  I need to be alert and on top of my mental game at work.  With the current nausea, I am a mess before 10:00am every day, then it gets better.

Has anyone else out there been down this same path, and if so, how did if affect you?  I know everyone reacts differently, but I need some assurance these days.  I only get scared when I read all these posts.

Offline allanq

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Re: Sustiva/Combivir to Atripla - anyone else?
« Reply #1 on: July 01, 2007, 02:09:16 AM »
I experienced severe nausea when I was taking AZT, to the point where I was throwing up several times a day, and just the smell of food would make me nauseous. The nausea stopped when I got off the AZT.

I think the switch from Sustiva/Combivir to Atripla will probably stop the nausea for you. Atripla consists of Sustiva + Viread + Emtriva. Combivir consists of AZT + Epivir. I've taken Viread and did not have any problems with nausea.

Good luck, and let us know how things go after the switch.


Top (Breakfast): Prezista, Norvir, Isentress, Zoloft (2), Glyburide (2), Aspirin
Bottom right (Dinner): Prezista, Norvir, Isentress
Bottom left (Bedtime): Sustiva, Trazodone (2), Lipitor, Septra (no longer taking this)
Center: Alprazolam (Xanax)
Not shown: various vitamins & supplements


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Re: Sustiva/Combivir to Atripla - anyone else?
« Reply #2 on: July 03, 2007, 06:15:14 PM »
Thanks Allan.  My Atripla hasn't arrived yet, but I can't wait to switch.  I'll let you know how it goes.


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Re: Sustiva/Combivir to Atripla - anyone else?
« Reply #3 on: August 11, 2007, 11:58:30 PM »
It's been over a month now and the Atripla seems to be a better choice for me.  I have not had any blood work since making the switch, but my nausea has mostly subsided.  Instead of every day, it's now maybe two times a week.  I feel a bit more energetic too, although my dreams are still very intense and I have trouble getting to sleep and getting up in the morning for work.  It's still better than feeling like I am going to vomit all the time.

My body shape has changed a little and I have lost weight, but that has been since January or so (was on Combivir and Sustiva since March 06).  Legs and arms are a little thinner, but my ass has completely disappeared.  Nothing I can notice in my face or anything.

So far, so good...I hope I will be good for a while now.


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