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Author Topic: restarting meds (UPDATE)  (Read 5426 times)

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Offline anniebc

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  • Posts: 5,939
  • AM member since 2003
restarting meds (UPDATE)
« on: July 25, 2007, 06:43:29 AM »
Hi all

After being on a forced drug holiday for 7 months I will be restarting a new combo in the morning.

Norvir..1 daily-100mg
Reyataz..2 daily-150mg
Tenofovir..1 daily-300mg
Emtriva (FTC) 1 daily-200mg

I came off my last combo in December..CD4 was 1080..%66 and VL <50
numbers are now CD4 360..%29 and VL 90,000..so I figured it was time, I didn't see any point in waiting for my CD to drop anymore.

I was a little apprehensive at first about starting a new combo but now I see them they don't look so scary anymore... ;)

I have had it on very good authority that it's a good combo with very little side effects so I'm keeping my fingers crossed.

I would like to say thanks to Rab and Gerry who both gave me some very good advise and helped keep me sane while I was deciding what to do and when to do it.

Hugs to you all
Jan :-*

« Last Edit: August 01, 2007, 05:30:26 AM by anniebc »
-----------------------------------------------------------------------
Never knock on deaths door..ring the bell and run..he really hates that.

Offline Cliff

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Re: restarting meds
« Reply #1 on: July 25, 2007, 07:21:26 AM »
Good luck with the new combo Jan!  It's the exact same one I was on.  It worked well for me.  I had no major side-effects.  The first two weeks my eyes turned slightly yellow (I noticed it more than others).  And sometimes my stool was softer than normal (and were slightly yellowish/light brownish).  The doctor said that was probably a combination of the norvir and fatty foods (it was better when I ate oatmeal).  My bilirubin (sp?) increased significantly, but the doctor said that it was harmless.

Overall I was satisfied with combo...and hopefully you will too.

Offline Dachshund

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  • Posts: 5,958
Re: restarting meds
« Reply #2 on: July 25, 2007, 07:24:25 AM »
Being the total homo that I am I will quote from the 1967 classic Valley of the Dolls. Being the totally groovy chick that you are I know you will get it. All you other goobers will need to scratch your heads or google.

       You've got to climb Mount Everest to reach the Valley of the Dolls

                                             ~Anne Welles
                                             (as played by Barbara Parkins)
      

Offline Razorbill

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Re: restarting meds
« Reply #3 on: July 25, 2007, 08:02:43 AM »
Jan - You will more than likely do well on your new combo.  It's minimally troublesome.  I like it fine.  I wonder why you're taking Tenofovir and Emtriva, instead of one pill, Truvada.  It would save you a co-pay and a pill a day. The bilirubin issue is usually not visible, except for some.  Good luck to you.

Offline cjc

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  • Sweet Girl
Re: restarting meds
« Reply #4 on: July 25, 2007, 08:21:56 AM »
Jan, Good luck with your new meds. Hope the sides are non-existant and you feel great.  Cristy

Offline Nadine

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Re: restarting meds
« Reply #5 on: July 25, 2007, 08:30:24 AM »
Best of luck to you dear lady!  :-*
(((HUGS)))

Offline emeraldize

  • Member
  • Posts: 3,348
Re: restarting meds
« Reply #6 on: July 25, 2007, 08:38:17 AM »
Hi Jan
Razorbill makes a good point. I hope the restart goes well for you.
Em

Offline Life

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  • Member 2005
Re: restarting meds
« Reply #7 on: July 25, 2007, 09:08:19 AM »
Jan,  your going to be ok,  "you will be"...   Use those tools you learned back in your (other) career day..  We love you honey... 

Eric

Offline RapidRod

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Re: restarting meds
« Reply #8 on: July 25, 2007, 11:52:12 AM »
Jan, if you don't scare the meds and they don't jump from your hand, then they are good to take.  ;) I hope your new combo works for you.

Rodney

Offline MSPspud

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  • Joined Mar 2005 - Formerly UofMurbs
Re: restarting meds
« Reply #9 on: July 25, 2007, 12:24:49 PM »
Best of luck, Jan.  Please let us know how it all shakes out with your liver enzymes too.  I find it amazing that you were able to stay undetectable on half doses on your prior regmine.  I hope this one works out for you.

Offline Blixer

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Re: restarting meds
« Reply #10 on: July 25, 2007, 02:08:31 PM »
Jan,
Best of luck with the new combo.  It sounds like the track record for that combo is great! 
David
Diagnosed 1/9/06
8/27/2007 CD4 598, 29%, VL 58 (72 wks)
11/19/2007 CD4 609, 30%, VL < 50 (84 wks)
2/11/2008 CD4 439, 27%, VL <50 (96 wks)
5/5/2008 CD4 535, 28%, VL <50 (108 wks)
10/20/2008 CD4 680, 28%, VL <50 (132 wks)
Changed to Atripla in 2012
1/14/2013 CD4 855, 35%, VL <40

Offline manchesteruk

  • Member
  • Posts: 630
Re: restarting meds
« Reply #11 on: July 25, 2007, 02:29:02 PM »
Good luck with the new combo Jan.  What happened with the last one that caused you to take a break if you don't mind me asking?

Chris
Diagnosed 11/05

"Life is too important to be taken seriously" Oscar Wilde

Offline Robert

  • Member
  • Posts: 2,644
Re: restarting meds
« Reply #12 on: July 25, 2007, 04:12:42 PM »
hi jan.'

wow...you really dipped fast, didn't you?  Some people go on holiday for 2 (i.e. Cliff (2 and counting)) or 3+  (Brandon) years.  Sorry you have to start up so soon.

yeah, it is a good combo and relatively benign.  I've been on it for 3 1/2 years and have gone  from 19 t-cells to over 500.  I take it you don't have Truvada yet in your part of the world.  Truvada is the Tenofovir and the Emtriva combined into one.  It's one pill instead of 2 so it might be a little more convenient and it saves on a co-pay but that might not be an issue. 
3 pills.  4 pills.  It's no biggy.

robert
..........

Offline keyite

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Re: restarting meds
« Reply #13 on: July 25, 2007, 04:19:35 PM »
Hope the new one works out well. Like Manchester I'm curious about why you stopped the previous regime?

Offline penguin

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Re: restarting meds
« Reply #14 on: July 25, 2007, 05:02:59 PM »
best of luck with the new stuff  :)

Kate x

Offline DanielMark

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Re: restarting meds
« Reply #15 on: July 25, 2007, 05:20:21 PM »
Hope the restart goes well, Jan!
MEDS: REYATAZ & KIVEXA (SINCE AUG 2008)

MAY 2000 LAB RESULTS: CD4 678
VL STILL UNDETECTABLE

DIAGNOSED IN 1988

Offline sdcabincrew74

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Re: restarting meds
« Reply #16 on: July 25, 2007, 05:25:49 PM »
Jan,

I am on Reyetaz, Norvir and Truvada, it is wonderful combo without many side effects.  However, FYI, Reyetaz comes in a 300 MG tablet too now which reduces your pill number by one .... it makes it fit in my little pill box better.  Just something to consider when it comes time to order refills.
The difference between an overnight and a layover is luck!

Offline sweetasmeli

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  • Love what you are...
Re: restarting meds
« Reply #17 on: July 25, 2007, 06:15:49 PM »
Jan honey, best wishes for a smooth ride with the new combo.

Many hugs
Melia :-*
/\___/\       /\__/\
(=' . '=)    (=' . '=)
(,,,_ ,,,)/   (,,,_ ,,,)/ Cats rule!

The difference between cats and dogs is that dogs come when called, whereas cats take a message and get back to you.

Yeia kai hara (health and happiness) to everyone!

Offline Matty the Damned

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  • Ninja Please
Re: restarting meds
« Reply #18 on: July 25, 2007, 07:16:39 PM »
Hey Janno,

Yup it's a good combo. Of all the protease inhibitor combos norvir/reyataz is probably the easiest to tolerate. I've got no doubt you'll do fine here babe.

:-*

MtD

Offline anniebc

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  • Posts: 5,939
  • AM member since 2003
Re: restarting meds
« Reply #19 on: July 25, 2007, 07:17:52 PM »
Hi everyone

Thank you for all your replies...just taken my first lot, Damn that Norvir is a big bugger isn't it..but it does down well..(don't even think about it Rod.. ;))

Hal..not so sure about the "groovy" thing..I can only assume that the line from Valley of the dolls means something along the lines of "you have to get high first before you can start coming down"..am I anywhere near close?.. :D

Just to answer a couple of your questions:

Truvada is not available in these parts yet, I did check it out with my ID Doc.

Spud, Chris, Keyite ..although my last combo..Ziagen and 3TC was an atypical combo it worked well for me for a couple of years..but unfortunately it messed up my Liver functions in the end so I had to come off them...LFT's are all good now.

Sdcab..i wasn't aware that Reyataz came in 300mg, I already have my 3 month supply so I'll stick with this until they are finished and then talk to my Doc about the higher dose.

Robert..I was hoping I would be one of these who could stay off the meds for a year or so...I'm not sure why my numbers fell so quickly, I know that the young man I got the needle stick from had a very nasty strain and was extremely ill and has since passed away, but I'm really not sure if that has anything to do with it, to be honest I have never really looked into it.

Thanks again for all your support I'm sure everything is going to be fine, but if I have any problems I'm sure I can manage them, it's good to be a control freak sometimes... ;)

Hugs to you all
Jan :-*


-----------------------------------------------------------------------
Never knock on deaths door..ring the bell and run..he really hates that.

Offline Matty the Damned

  • Member
  • Posts: 12,228
  • Ninja Please
Re: restarting meds
« Reply #20 on: July 25, 2007, 07:22:57 PM »
i wasn't aware that Reyataz came in 300mg, I already have my 3 month supply so I'll stick with this until they are finished and then talk to my Doc about the higher dose.

I get my Reyataz in 150mg caps as well babe. I just take both at once. I've heard of the 300mg version but I don't think it's available in Australia. Since Oz and En Zed tend to work together when it comes to this sort of stuff, I doubt if the 300mg is available on your side of the ditch either.

MtD

Offline anniebc

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  • AM member since 2003
Re: restarting meds
« Reply #21 on: July 25, 2007, 07:29:39 PM »
Thanks Matty, I'm sure that's the case, my ID Doc is pretty much up to date with everything and I'm sure he would have prescribed the 300mg if it was available.

Hope you are feeling a little better today.

Hugs
Jan :-*
-----------------------------------------------------------------------
Never knock on deaths door..ring the bell and run..he really hates that.

Offline AlanBama

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  • Alabama: the 'other' 3rd World Country!
Re: restarting meds
« Reply #22 on: July 25, 2007, 08:51:24 PM »
Good luck with the new regimen honey.....

You know you are in my prayers.


Love,

Alan
"Remember my sentimental friend that a heart is not judged by how much you love, but by how much you are loved by others." - The Wizard of Oz

Offline aztecan

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  • Posts: 5,398
  • 29 years positive, 57 years a pain in the butt
Re: restarting meds
« Reply #23 on: July 25, 2007, 09:05:21 PM »
Jan Love,

I hope the combo is working well for you. Yes, the Norvir is HUGE! I have never had trouble swallowing large thing. I am glad a dainty lady like yourself was able to down it without problem.

We are on similar combos, except you are on Truvada (or the equivalent thereof), and I am on Combivir, which is a combination of AZT and Epivir, the latter of which, if memory serves, you took before but had problems with, right?

From what I hear, your NRTIs are very good and well tolerated by many. As for the Reyataz/Norvir, well, I have no problems with them at all.

Please let us know how you are doing. You know I will be sending only the best, most positive energy your way.

HUGS,

Mark
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline RapidRod

  • Member
  • Posts: 15,288
Re: restarting meds
« Reply #24 on: July 25, 2007, 10:38:42 PM »
Quote
Thank you for all your replies...just taken my first lot, Damn that Norvir is a big bugger isn't it..but it does down well..(don't even think about it Rod.. )

Jan, I'm not going to reply to that until we are in SF when we can have it on webcast.  :D

Offline Robert

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  • Posts: 2,644
Re: restarting meds
« Reply #25 on: July 25, 2007, 11:50:48 PM »
Jan...

If you don't havet the Truvada yet, you certainly don't have the 300mg Retataz.  I started the Truvada a year ago and only the 300mg Reyataz just last April.  It's real new.  Like I said, it really doesn't make much difference.

  1 pill, 2 pills, 3 pills, 4
  chug 'em down and go out the door.
  and soon never more
..........

Offline Basquo

  • Member
  • Posts: 3,258
Re: restarting meds
« Reply #26 on: July 26, 2007, 12:00:54 AM »
Go Jan!  I know you'll do fine, and you know how to deal with any bumps in the road.  You also have the greatest reason to get out and be active...all those babies behind your house depend on their mama! I bet this new combo doesn't even faze you...

Offline StrongGuy

  • Member
  • Posts: 492
Re: restarting meds
« Reply #27 on: July 26, 2007, 01:46:15 AM »
Best of luck, Jan!

You'll do great. And if you have some issues, we'll all be here to help ya through!
"Get your medical advice from Doctors or medical professionals who you trust and know your history."

"Beware of the fortune teller doom and gloomers who seek to bring you down and are only looking for company, purpose and validation - not your best physical/mental interests."

"You know you all are saying that this is incurable. When the real thing you should be saying is it's not curable at the present time' because as we know, the great strides we've made in medicine." - Elizabeth Edwards

Offline fearless

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Re: restarting meds
« Reply #28 on: July 26, 2007, 02:53:02 AM »
Best of luck, Jan.

I'm sure you'll be fine and those numbers will bounce back to where you'd like them.
Be forgiving, be grateful, be optimistic

Offline Christine

  • Member
  • Posts: 1,069
Re: restarting meds
« Reply #29 on: July 26, 2007, 05:21:45 PM »
Hi Jan,
Sending you good wishes, positive thoughts, good vibes...all that good stuff that the combo treats you well.

I agree with what Cliff said about eating fats. I seem to go better with more protein, and limiting fatty foods.

How are all your fur-babies doing?

Christine
Poz since '93. Currently on Procrit, Azithromax, Pentamidine, Valcyte, Levothyroxine, Zoloft, Epzicom, Prezista, Viread, Norvir, and GS-9137 study drug. As needed: Trazodone, Atavan, Diflucan, Zofran, Hydrocodone, Octreotide

5/30/07 t-cells 9; vl 275,000

Offline Carolann

  • Member
  • Posts: 233
Re: restarting meds
« Reply #30 on: July 26, 2007, 10:14:49 PM »
Good Luck. I will be restarting too, at the first sign of any oi. Looks like your combo is a winner. Best of luck!

CA

Offline Queen Tokelove

  • Member
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  • Smokey the Smurf
Re: restarting meds
« Reply #31 on: July 26, 2007, 10:49:43 PM »
Wishing you the best on your restart...Keep us posted on how you're doing..... :-*
Started Atripla/Ziagen on 9/13/07.
10/31/07 CD4-265 VL- undetectable
2/6/08 CD4- 401 VL- undetectable
5/7/08 CD4- 705 VL- undetectable
6/4/08 CD4- 775 VL- undetectable
8/6/08 CD4- 805 VL- undetectable
11/13/08 CD4- 774 VL--undetectable
2/4/09  CD4- 484  VL- 18,000 (2 months off meds)
3/3/09---Starting Back on Meds---
4/27/09 CD4- 664 VL-- undetectable
6/17/09 CD4- 438 VL- 439
8/09 CD4- 404 VL- 1,600
01-22-10-- CD4- 525 VL- 59,000
Cherish the simple things life has to offer

The Royal Blog

Offline Jody

  • Member
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Re: restarting meds
« Reply #32 on: July 27, 2007, 03:33:49 AM »
Best of luck on your new combo Jan and keep us posted on how you are doing.

Jody
"Wake up to find out that you are the eyes of the world".
 "Try to discover that you are the song that the morning brings."

Grateful Dead

Offline blondbeauty

  • Member
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Re: restarting meds
« Reply #33 on: July 27, 2007, 06:53:32 AM »
Good luck Jan. Let us know how you feel these days.  ;) :-* :-* :-*
The only member in these forums approved by WINBA: World International Nail and Beauty Association.
Epstein Barr +; CMV +; Toxoplasmosis +; HIV-1 +.
Counts when starting treatment:
V.L.:80.200 copies. CD4: 25%=503
Started Sustiva-Truvada 14/August/2006
Last V.L.count (Oct 2013): Undetectable
Last CD4 count (OCT 2013): 52%= 933

Online Andy Velez

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Re: restarting meds
« Reply #34 on: July 27, 2007, 08:43:09 AM »
Fingers and other body parts crossed for you, Jan, and expecting the new combo to work out well for you. Sounds like it's a well thought out move.

Big cheers and hugs, 
Andy Velez

Offline Erico

  • Member
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Re: restarting meds
« Reply #35 on: July 27, 2007, 07:08:13 PM »
Bonne chance Jan

Hugs

Erico

Offline anniebc

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Re: restarting meds (UPDATE)
« Reply #36 on: August 01, 2007, 05:39:36 AM »
Hi Everyone

Just thought I would let you know how the new combo is going.

The first 3 days were not the best, nausea, headaches and just generally feeling unwell..it threw my morning routine out of whack because I couldn't really get out of the house until everything settled down..(My babies did not appreciate missing breakfast)

Four days ago I started taking my meds at night just before going to bed..and feel great, I can get on with evrything as I did before and have no side effects during the day at all, so all in all I think this is going to work for me, apart from the fact my face is now a lovely mustard color, but I'm sure that will soon pass.. ;)

My first bloods will be drawn at the end of this month so we will see if the meds are doing their job.

Thanks again for all you support.

Hugs to you all
Jan :-*
-----------------------------------------------------------------------
Never knock on deaths door..ring the bell and run..he really hates that.

Offline RapidRod

  • Member
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Re: restarting meds (UPDATE)
« Reply #37 on: August 01, 2007, 06:40:43 AM »
Quote
apart from the fact my face is now a lovely mustard color

You need to change your night facial cream.  ;) Get a white or a pretty green.  ;) Just make sure you remove it before you go shopping.  :D

Offline jack

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  • fomerly the loser known as Jake
Re: restarting meds (UPDATE)
« Reply #38 on: August 01, 2007, 09:51:24 AM »
I had horrible sides from Reyataz.Never had the yellow thing but did have involuntary diarrhea as well as nuclear diarrhea 24/7. Bummer. Also gained 40 pounds in first five weeks around neck and back. After 6 months my vl started back up.  There is always the miracle drug Prezista.

Offline AlanBama

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  • Alabama: the 'other' 3rd World Country!
Re: restarting meds (UPDATE)
« Reply #39 on: August 01, 2007, 10:20:16 AM »
Glad you are doing better with it Jan!

Tip:   Don't wear yellow -- it will clash with your skin!  Hopefully that problem will begin to resolve itself also...

love you,

Alan   :-*
"Remember my sentimental friend that a heart is not judged by how much you love, but by how much you are loved by others." - The Wizard of Oz

Offline Robert

  • Member
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Re: restarting meds (UPDATE)
« Reply #40 on: August 01, 2007, 11:19:43 AM »
 Well, I bet your babies are glad you're getting back to your old self.  Breakfast is such an important meal for ALL of God's little creatures. 

Of course it goes without saying, I'm glad the meds are doing what they're supposed to and you've got a good schedule down.  As for the yellowing?  It too shall pass.

robert
..........

Offline J.R.E.

  • Member
  • Posts: 7,162
  • Joined Dec-2003 Living positive, since 1985.
Re: restarting meds (UPDATE)
« Reply #41 on: August 01, 2007, 07:36:49 PM »
Hello Jan,

I am trying to catch up on some of the threads. Sorry to hear about the rough start on the new regemin, Wishing you the best !! Hang tough !!



(((HUGS)))-----Ray
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 12.5mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


 In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started my first  HAART regimen  on October 24th,03.

 As of 8/2514,  t-cells are at 402, Viral load <40

 Current % is at 11%

  
 62 years young.

Offline randym431

  • Member
  • Posts: 1,125
Re: restarting meds (UPDATE)
« Reply #42 on: August 06, 2007, 09:24:53 AM »
Hi Jan
I don’t seem to keep up here on the forum too much anymore. Heres wishing you the best with your restart.
Reading your post brought something to mind. For me, its been a fairly smooth, but long road to getting back to kilt with the meds. Now a days, and for some time, I hardly think about being hiv. And popping the pills once a day has become like cleaning my glasses before wearing them, something I do without thinking of it.
Some days I even feel I am "cured" just because I no longer have to deal with this, since the meds work so well (for me).
But reading your post reminds me that this "thing" in us would gladly try to take over, again, if it could get a chance.
Even though I take the meds each and every day, not missing once since the start in 09 of 2005, I find it easy to pretend that if I was not on meds, the virus would just stay away.
It doesn’t work like that. A little wakeup, reality check for me in reading your post.

BTW, Thanks so much again for that lovely painting you sent me some time back. Just last week two ladies, one a cousin of my partner and the other her lover, stopped in on their way back to MN from their Branson vacation and they ask all about the painting, which they loved. I feel so privileged to have it. And a physical link to you way over there in BC.
Ps.. A note, the day they left was the day the bridge fell in, up in MN. They live in Minne and took that freeway, but did not cross that bridge on the way home. But kinda eerie anyhow.
Take care... Randy
« Last Edit: August 06, 2007, 09:28:01 AM by randym431 »

 


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