Quantcast

Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
July 24, 2014, 12:16:00 PM

Login with username, password and session length


Members
  • Total Members: 23024
  • Latest: louis80
Stats
  • Total Posts: 631733
  • Total Topics: 47825
  • Online Today: 266
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: GeoVax Announces Start of 2 New HIV/AIDS Vaccine Human Trials  (Read 2312 times)

0 Members and 1 Guest are viewing this topic.

Offline J220

  • Member
  • Posts: 587
Speaking of the promising Geovax vaccine, the company behind it put out the following press release today. Everything is moving ahead perfectly, even ahead of schedule! Although the main focus for this vaccine is preventive, the company is concurrently developing with therapeutic purposes in mind. The original link is: http://www.geovax.com/newsroom/press_release_new_trials_jul07.pdf . Great things are on the way, people! J.

_______________________________

FOR IMMEDIATE RELEASE

17 July 2007

GeoVax Announces Start of 2 New HIV/AIDS Vaccine Human Trials


ATLANTA, Ga., 17 July 2007 – GeoVax Labs, Inc. (OTC BB: GOVX), an Atlanta-based biotechnology company, announced an early start of 2 new AIDS vaccine clinical (human) trials. These FDA compliant trials were previously scheduled to start later in 2007 and are the 3rd and 4th in a 4 clinical trial series intended to evaluate both human safety and immune responses to GeoVax’s HIV/AIDS vaccines.

GeoVax’s vaccines are designed to prevent Acquired Immunodeficiency Disease (“AIDS”) in humans caused by the virus known as HIV-1 (Human Immunodeficiency Virus), by vaccinating individuals with its DNA and MVA vaccines prior to infection with the virus.

Starting April 2006, the 1st of these 4 human trials evaluated a low dose (1/10th of the vaccine dose) vaccination program. Preliminary results from this blinded trial demonstrated excellent vaccine safety and positive anti-HIV-1 immune responses to the vaccine in 9 of 11 participants where 9 people received GeoVax HIV/AIDS vaccines and 2 received placebos. All trial participants were normal healthy individuals. Final results will be compiled for later public release.

The 2nd of 4 human trials, initiated September 2006, was designed to evaluate results from full dose administration of GeoVax HIV/AIDS vaccines. Recent data indicates excellent safety in this full dose trial. Additional results from ancillary testing conducted at Emory University by Dr. Harriet Robinson demonstrated positive anti-HIV-1 immune responses in the majority of vaccine recipients. Official immune response data will be available later this year.

Excellent results from the 1st and 2nd trial of this 4 trial series have allowed the accelerated start of human trials #3 and #4. These trials began more than a month earlier than originally anticipated.

Due to exceptionally good results, GeoVax’s scientific team believes its vaccine may perform equally as well in trial #3 which administers fewer vaccine doses and trial #4 which utilizes only GeoVax’s MVA vaccine. “Success in these trials could lead to a simpler vaccine regime making it easier to vaccinate people,” stated Dr. Harriet Robinson, PhD., GeoVax’s Co-founder and Scientific Advisory Board Chairperson.

Don Hildebrand, GeoVax CEO/President/Co-founder, commented, “We are pleased with the results obtained to date from our ongoing full dose vaccine human trial. The excellent vaccine safety profile demonstrated was key to accelerating the start date of these new human trials. Equally important are the positive immune responses observed in people receiving only 1/10th of a dose of our vaccines. This is very encouraging news".
"Hope is my philosophy
Just needs days in which to be
Love of Life means hope for me
Born on a New Day" - John David

Offline Jake72

  • Member
  • Posts: 145
Re: GeoVax Announces Start of 2 New HIV/AIDS Vaccine Human Trials
« Reply #1 on: July 17, 2007, 06:36:17 PM »
Great, J220!  Thanks for posting this! 

Just as a reference, here was a 'mainstream press' piece on the vaccine from April, and it does make mention of the therapeutic possibilities:

http://www.11alive.com/news/article_news.aspx?storyid=93439




Offline jack

  • Member
  • Posts: 1,578
  • fomerly the loser known as Jake
Re: GeoVax Announces Start of 2 New HIV/AIDS Vaccine Human Trials
« Reply #2 on: July 17, 2007, 07:00:13 PM »
I hope this isnt some kind of scam. If you check the stock of this company its 27cents a share. Not good. Apparently not many share their  enthusiasm.

Offline JamieD

  • Member
  • Posts: 259
Re: GeoVax Announces Start of 2 New HIV/AIDS Vaccine Human Trials
« Reply #3 on: July 17, 2007, 08:10:20 PM »
Yeah, studies that have 11 people in them can look very promising. It's when you get to phase 2 and 3 clinical trials that things go down hill from there.

I hate how the media tries to turn phase 1 clinical trials into the next biggest thing since sliced bread. They did that with Inderal and PTSD. The study they were touting as the end of bad memories, was a phase 1 clinical trial involving less then 100 people. Then they reported on what the Bush Administration had to say and blah blah blah and it was just ridiculous all over a phase 1 clinical trial.
It's also what I hate about "alternative" medicine. Most alternative medicine quacks, like Dr. Mercola, take the smallest of clinical trials or in vitro studies and hail them as a miracle from above, and this particular thing will cure every single disease known to man.
« Last Edit: July 17, 2007, 08:18:57 PM by JamieD »

Offline J220

  • Member
  • Posts: 587
Re: GeoVax Announces Start of 2 New HIV/AIDS Vaccine Human Trials
« Reply #4 on: July 17, 2007, 08:20:50 PM »
I hope this isnt some kind of scam. If you check the stock of this company its 27cents a share. Not good. Apparently not many share their  enthusiasm.

I agree the stock is close to flatlining, but I don't think it means it's a scam. After all, this company is affiliated to Emory University, and the vaccine research was developed in collaboration with the NIH. Below is a summary of the company from my online trading account:

_________________________________________________________________

GeoVax Labs, Inc. (GeoVax), formerly Dauphin Technology, Inc. (Dauphin), is a clinical stage biotechnology company engaged in research and development activities to develop, license and commercialize the manufacture and sale of human vaccines for diseases caused by human immunodeficiency virus (HIV) and other infectious agents. The Company has licensed from Emory University certain acquired immune deficiency syndrome (AIDS) vaccine technology, which was developed in collaboration with the National Institutes of Health and the Centers for Disease Control and Prevention. On September 28, 2006, Dauphin completed a merger (the Merger) with GeoVax, Inc. Pursuant to the agreement and plan of merger, GeoVax, Inc. merged with and into GeoVax Acquisition Corp., a wholly owned subsidiary of Dauphin. In connection with the Merger, Dauphin changed its name to GeoVax Labs, Inc.

______________________________________________________

Now, as far as where they stand on the research, yes it could go either way. But what they are sharing so far seems encouraging. It doesn't hurt to hope, and keep an eye on this vaccine. J.
"Hope is my philosophy
Just needs days in which to be
Love of Life means hope for me
Born on a New Day" - John David

Offline messer

  • Member
  • Posts: 21
Re: GeoVax Announces Start of 2 New HIV/AIDS Vaccine Human Trials
« Reply #5 on: August 01, 2007, 06:19:40 PM »
And now, a GeoVax therapeutic trial for 2008.      Excitement anyone?      GeoVax is solid.    They just earned an investment of 7.5 million dollars from a private investment firm.     Thats in addition to 9m already raised by private investors.       Anyone know, based on the GeoVax vaccine formulation, with antibodies and t-cells being produced by the body, would the vaccine go after the little nasties hiding out in the reservoirs?    What would that mean?

Offline Jake72

  • Member
  • Posts: 145
Re: GeoVax Announces Start of 2 New HIV/AIDS Vaccine Human Trials
« Reply #6 on: August 01, 2007, 07:34:21 PM »
Here's a link discussing what Messer was talking about:

http://www.geovax.com/newsroom/press_release_funding_jul07.pdf


 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.