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Author Topic: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!  (Read 2579 times)

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Offline LA Dude

  • Member
  • Posts: 7
I already posted about Atripla making me nutty, BUT now I can't sleep. My Combivir and Viramune were working just fine. but my doctor talked me into changing to Atripla. I have never been much of a drinker and I don't do drugs, because I hate that dull, high, and/or out of control feeling. NOW- that is my life 24/7!!!!!

This is THE single greatest regret of my 7 years of treatment.

I'm still trying to find out if I can go back on Combivir and Viramune. It seems like I read somewhere that I cannot. I am an honor student about to start grad school, but I feel like my IQ is now half of what it was before.

I will see another doctor at the clinic on Tuesday, but he wants me to start a Protease Inhibitor. I am scared about starting on one of those as I worry about lipodystrophy, getting a belly, or whatever else could happen.

Any advice from physicians or anyone with knowledge on my delima would be MUCH appreciated.

Offline ARMANDO

  • Member
  • Posts: 255
Re: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!
« Reply #1 on: June 25, 2007, 08:48:26 AM »
sure you can switch back,i don't know why you switched  in the first place if you were getting good results with the old combo.BEST thing to do is get a genotype to find out if you have developed no resistance to the old combo.once you find a combo that works ,you shouldn't change it just for the sake of trying something NEW!!!

Offline aztecan

  • Member
  • Posts: 5,414
  • 29 years positive, 57 years a pain in the butt
Re: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!
« Reply #2 on: June 25, 2007, 07:38:08 PM »
Hey Dude (I've always wanted to say that!  :D)

As long as you didn't develop resistance with the other meds, I don't know why you can't go back to them. Has your doc said something about not going back on the Viramune or Combivir?

I feel for you regarding Atripla. When I started Sustiva, I thought I would never be able to adjust to it. I seem to be doing much better now, although sometimes still foggy. It took two months for it to settle down for me.

Regarding the PI, not everyone develops the lipodystrophy issues, and some are less prone than others for this.

I would have a serious heart-to-heart with your doctor, explain what's going on and your concerns about the PIs. There has to be a happy medium for you out there.

HUGS,

Mark
"May your life preach more loudly than your lips."
~ William Ellery Channing (Unitarian Minister)

Offline J.R.E.

  • Member
  • Posts: 7,259
  • Joined Dec-2003 Living positive, since 1985.
Re: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!
« Reply #3 on: June 25, 2007, 08:57:46 PM »
Hello,

As long as you didn't have a hypersensitive reaction to the viramune, I am not sure why you can't switch back to that drug. This is the only time I am aware that Viramune should not be restarted. What are your current t-cell numbers?
Also, how were your liver function tests, while on viramune ?
I am not sure whether it would have to be started again in half doses or not, for a two week period.


Keep us posted------Ray
« Last Edit: June 25, 2007, 09:00:55 PM by J.R.E. »
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 25 mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


Diagnosed positive in 1985,.. In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started on  HAART on October 24th, 2003.

 As of 8/25/14,  t-cells are at 402, Viral load <40

 Current % is at 11%

  
 62 years young.

Offline redhotmuslbear

  • Member
  • Posts: 605
  • A genuine certified freak of nature, and a hot one
Re: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!
« Reply #4 on: June 26, 2007, 11:02:19 AM »
I will see another doctor at the clinic on Tuesday, but he wants me to start a Protease Inhibitor. I am scared about starting on one of those as I worry about lipodystrophy, getting a belly, or whatever else could happen.  Any advice from physicians or anyone with knowledge on my delima would be MUCH appreciated.

Dude,
As a full-time professional and a part-time grad student, I totally agree with having to be on top of your mental game!

You mention "another doctor at the clinic?"  I take this as meaning a public health setting where you have some sort of case management available, apart from medical care.  You need to call a case manager NOW and be very assertive about the diminshed quality of life you are experiencing.  Then, when you see the doctor, explain why you WILL NOT take another pill with Sustiva and why you do not want to take protease inhibitors now, then put Viramune on the table as an option that will keep you from moving to another drug glass while escaping the horror of Sustiva.

Best,
David
"The real problem is not whether machines think but whether men do." - BF Skinner
12-31-09   222wks VL  2430 CD4 690 (37%)
09-30-09   208wks VL  2050  CD4 925 (42%)
06-25-08   143wks VL  1359  CD4 668 (32%)  CD8 885
02-11-08   123wks off meds:  VL 1364 CD4 892(40%/0.99 ratio)
10-19-07   112wks off meds:   VL 292  CD4 857(37%/0.85 ratio)

One copy of delta-32 for f*****d up CCR5 receptors, and an HLA B44+ allele for "CD8-mediated immunity"... beteer than winning Powerball, almost!

Offline BlkRedBonenla

  • Member
  • Posts: 85
    • My MySpace Page
Re: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!
« Reply #5 on: June 27, 2007, 12:40:02 AM »
Simple:

DON'T TAKE ATRIPLA AT BEDTIME
DON'T TAKE ATRIPLA AT BEDTIME
DON'T TAKE ATRIPLA AT BEDTIME!!!

I started meds 3months ago and with Atripla and could not sleep with it. I simply take it several hours BEFORE bedtime. That stoned/drunk feeling - which I also hate - sets in about 2 hours later and lasts for about 30-40 min. It's less intense if I stick to my vegetarian diet. But then I sleep beautifully!!!!

When you get home from work, take your pill, last out the evening, and by bedtime you should be fine.

Lowell
another LA dude!!
- cd4 20 2/07 & 50K VL

**** 3/07 started ATRIPLA *******
- cd4 70 5/07 & Undetectable VL
- cd4 218 11/07 & Undetectable VL
-cd4 297 3/08 & Undetectable VL
-cd4 439 1/09 & Undetectable VL
-cd4 436 4/09 & Undetectable VL
-cd4 442 8/09 & Undetectable VL
-cd4 512 11/09 & Undetectable VL
-cd4 531 2/10 & Undetectable VL
-cd4 439??? 6/10 & Undetectable VL ...


_____________________________________

"A little bit of knowledge is a dangerous thing, but some minds can only handle a little." - George Bernard Shaw

Offline LA Dude

  • Member
  • Posts: 7
Re: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!
« Reply #6 on: June 27, 2007, 03:31:32 AM »
Thanks for ALL the advice everyone!

I took my very last Atripla over 48 hours ago and had a great FULLY consciuos day today! No drunk/high/lethargic feeling at all!!!!

My awesome doctor put me back on Viramune 2x a day and Truvada once daily. We'll see how it goes.......

Offline J.R.E.

  • Member
  • Posts: 7,259
  • Joined Dec-2003 Living positive, since 1985.
Re: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!
« Reply #7 on: June 27, 2007, 07:32:52 AM »
Thanks for ALL the advice everyone!


My awesome doctor put me back on Viramune 2x a day and Truvada once daily. We'll see how it goes.......



Good Luck Dude !!


Ray
Current Meds ; Viramune, Epzicom, 40mg of simvastatin, 25 mg of Hydrochlorothiazide.
Metoprolol tartrate 25mg



http://forums.poz.com/index.php?topic=40802.0

http://forums.poz.com/index.php?topic=45159.0

http://forums.poz.com/index.php?topic=39722.msg495621;topicseen#msg495621

http://forums.poz.com/index.php?topic=46806.0

http://forums.poz.com/index.php?topic=39414.msg491701#msg491701


Diagnosed positive in 1985,.. In October of 2003, My t-cell count was 16, Viral load was over 500,000, Percentage at that time was 5%. I started on  HAART on October 24th, 2003.

 As of 8/25/14,  t-cells are at 402, Viral load <40

 Current % is at 11%

  
 62 years young.

Offline milker

  • Member
  • Posts: 4,034
  • Protected phone sex
Re: It's 5 am. I can't sleep! I HUGELY regret changing to Atripla!!!!!
« Reply #8 on: June 27, 2007, 11:04:05 AM »
Bro, that's awesome! Keep cool, Dawg!

Lates, Dude.

Milker.
mid-dec: stupid ass
mid-jan: seroconversion
mid-feb: poz
mar 07: cd4 432 (35%) vl 54000
may 07: cd4 399 (28%) vl 27760
jul 07: cd4 403 (26%) vl 99241
oct 07: cd4 353 (24%) vl 29993
jan 08: cd4 332 (26%) vl 33308
mar 08: cd4 392 (23%) vl 75548
jun 08: cd4 325 (27%) vl 45880
oct 08: cd4 197 (20%) vl 154000 <== aids diagnosis
nov 2 08 start Atripla
nov 30 08: cd4 478 (23%) vl 1880 !!!!!!!!!!!!!!!!!!!!!!!!!!
feb 19 09: cd4 398 (24%) vl 430 getting there!
apr 23 09: cd4 604 (29%) vl 50 woohoo :D :D
jul 30 09: cd4 512 (29%) vl undetectable :D :D
may 27 10: cd4 655 (32%) vl undetectable :D :D

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