Quantcast

Subscribe to:
POZ magazine
E-newsletters
Join POZ: Facebook MySpace Twitter Pinterest
Tumblr Google+ Flickr MySpace
POZ Personals
Sign In / Join
Username:
Password:
Welcome, Guest. Please login or register.
September 18, 2014, 08:25:03 PM

Login with username, password and session length


Members
Stats
  • Total Posts: 639333
  • Total Topics: 48532
  • Online Today: 223
  • Online Ever: 585
  • (January 07, 2014, 02:31:47 PM)
Users Online

Welcome


Welcome to the POZ/AIDSmeds Community Forums, a round-the-clock discussion area for people with HIV/AIDS, their friends/family/caregivers, and others concerned about HIV/AIDS.  Click on the links below to browse our various forums; scroll down for a glance at the most recent posts; or join in the conversation yourself by registering on the left side of this page.

Privacy Warning:  Please realize that these forums are open to all, and are fully searchable via Google and other search engines. If you are HIV positive and disclose this in our forums, then it is almost the same thing as telling the whole world (or at least the World Wide Web). If this concerns you, then do not use a username or avatar that are self-identifying in any way. We do not allow the deletion of anything you post in these forums, so think before you post.

  • The information shared in these forums, by moderators and members, is designed to complement, not replace, the relationship between an individual and his/her own physician.

  • All members of these forums are, by default, not considered to be licensed medical providers. If otherwise, users must clearly define themselves as such.

  • Forums members must behave at all times with respect and honesty. Posting guidelines, including time-out and banning policies, have been established by the moderators of these forums. Click here for “Am I Infected?” posting guidelines. Click here for posting guidelines pertaining to all other POZ/AIDSmeds community forums.

  • We ask all forums members to provide references for health/medical/scientific information they provide, when it is not a personal experience being discussed. Please provide hyperlinks with full URLs or full citations of published works not available via the Internet. Additionally, all forums members must post information which are true and correct to their knowledge.

  • Product advertisement—including links; banners; editorial content; and clinical trial, study or survey participation—is strictly prohibited by forums members unless permission has been secured from POZ.

To change forums navigation language settings, click here (members only), Register now

Para cambiar sus preferencias de los foros en español, haz clic aquí (sólo miembros), Regístrate ahora

Finished Reading This? You can collapse this or any other box on this page by clicking the symbol in each box.

Author Topic: syphilis titer question  (Read 6027 times)

0 Members and 1 Guest are viewing this topic.

Offline lydgate

  • Member
  • Posts: 1,022
  • Virgin, can't drive
syphilis titer question
« on: June 01, 2007, 05:37:38 PM »
I was treated for syph last year (six horribly painful injections in the glutes over three weeks). The titer wasn't that high to begin with 1:4. Came down to 1:2 after treatment.

Just had it checked again: it's 1:2 still. I'm told that's "normal," that it'll likely stay that way for life, and that I'm no longer -- gasp! -- syphilitic. (Is this what is called a "serofast reaction"?) But having this low titer for life doesn't mean I'm still infectious/contagious, does it? Or does it?

Second question: can you get reinfected with syphilis, or does one bout confer immunity through antibody generation/protection?

Jay
Her finely-touched spirit had still its fine issues, though they were not widely visible. Her full nature, like that river of which Cyrus broke the strength, spent itself in channels which had no great name on the earth. But the effect of her being on those around her was incalculably diffusive: for the growing good of the world is partly dependent on unhistoric acts; and that things are not so ill with you and me as they might have been, is half owing to the number who lived faithfully a hidden life, and rest in unvisited tombs.

George Eliot, Middlemarch, final paragraph

Offline Matty the Damned

  • Member
  • Posts: 12,228
  • Ninja Please
Re: syphilis titer question
« Reply #1 on: June 01, 2007, 05:49:03 PM »
Yes, you can be reinfected with syphilis and one bout does not confer immunity.

Three months after treatment for syphilis one expects to see a 4 four fold reduction in the titre. So ideally your titre should have gone from 1/4 to 1/1. Whilst it's quite common for people who have been treated successfully to return a reactive RPR with a titre of 1/1 for life, 1/2 is less common but if your doctor is happy with it then that's cool.

MtD

Offline lydgate

  • Member
  • Posts: 1,022
  • Virgin, can't drive
Re: syphilis titer question
« Reply #2 on: June 01, 2007, 09:52:33 PM »
Thanks Matty.

I don't think a lumbar puncture and CSF examination is necessary at this point. (Though that's the CDC recommendation for HIV-infected people treated for latent syphilis of unknown duration or of a duration longer than one year.)

Jay
Her finely-touched spirit had still its fine issues, though they were not widely visible. Her full nature, like that river of which Cyrus broke the strength, spent itself in channels which had no great name on the earth. But the effect of her being on those around her was incalculably diffusive: for the growing good of the world is partly dependent on unhistoric acts; and that things are not so ill with you and me as they might have been, is half owing to the number who lived faithfully a hidden life, and rest in unvisited tombs.

George Eliot, Middlemarch, final paragraph

Offline Matty the Damned

  • Member
  • Posts: 12,228
  • Ninja Please
Re: syphilis titer question
« Reply #3 on: June 01, 2007, 09:59:03 PM »
Yairs.

Normally CSF examination is performed in those who've had syphilis for a long time (10 years +) or those presenting with symptoms of tabes dorsalis, general paresis of the insane and other conditions associated with neurosyphilis, which is possibly the most ghastly manifestation of the disease.

HIV positive people tend to progress to tertiary syphilis much more quickly than negative people. Also HIV positive people with syphilis may suffer quite serious damage before any symptoms appear, so CSF examination is important in that sense.

Given your response to treatment (and I would expect that your titre will eventually drop to 1/1) and the view of your doctor, I would think that a lumbar puncture and CSF examination isn't warranted in your case.

MtD

 


Terms of Membership for these forums
 

© 2014 Smart + Strong. All Rights Reserved.   terms of use and your privacy
Smart + Strong® is a registered trademark of CDM Publishing, LLC.